This Solicitation opportunity from Department Of Health And Human Services was posted on March 14, 2025. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

Top

Final Innovative Solutions Opening (ISO) ARPA-H Rare Disease AI/ML for Precision Integrated Diagnostics (RAPID)

Closed

ARPA-H-SOL-25-119Federal

Submission Closed04/24/2025, 09:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

Active Opportunities Like This One

NAICS: 541715

New

Federal

Prototyping & Pilot Project ExecutionThis subcontract focuses on the prototyping and pilot project execution of innovative construction and delivery capabilities for prime contractors supporting Department of the Air Force 36 CONS projects. Operating under an Other Transaction Agreement framework, the scope of work involves implementing agile construction methods and testing emerging building technologies to deliver functional prototype or pilot-scale facilities. Managed by the Department of Defense agency FA5240 36 Cons Lgc, the project is categorized under NAICS code 541715. The primary objective is to advance construction capabilities through the practical application and testing of new technologies within a specialized military infrastructure context.

POSTED

DEADLINE

Synthesis and Distribution of Drugs of Abuse and Related Compounds

Solicitation # 75N98027R00006OT

National Institutes Of Health Nida

POSTED

DEADLINE

Synthesis and Distribution of Drugs of Abuse and Related Compounds

Solicitation # 75N98027R00006SB

National Institutes Of Health Nida

POSTED

DEADLINE

Bolstering Underutilized Industry by Leveraging Technology Transfer (BUILTT) pilot program

Solicitation # 10292026-LR-27

The Department of Energy, in partnership with the National Nuclear Security Administration, has announced the Bolstering Underutilized Industry by Leveraging Technology Transfer (BUILTT) pilot program. This initiative, conducted by the Nevada National Security Sites, Y-12 National Security Complex, and Kansas City National Security Campus, aims to assist qualified U.S. small and medium-sized businesses in manufacturing low-volume, high-impact technologies developed by DOE/NNSA Labs, Plants, and Sites. These technologies, which include specialized optical imaging, radiation and chemical sensing systems, precision electrical components, and advanced materials, often have limited commercial markets but are critical for government mission requirements. Under the program, selected businesses may receive a Cost Reduction License (CRL) for a nominal fee, granting them the rights to produce specified technologies for sale to the DOE, NNSA, and other government customers at pre-negotiated prices. Eligibility is limited to U.S.-based SMBs, with preference given to those near participating sites or those with SBA 8(a) or HUBZone designations. Interested parties are evaluated based on their technical and manufacturing capabilities, financial capacity, and ability to meet regulatory and security requirements. Responses must be submitted to the Technology Partnerships and Intellectual Property Office by April 1, 2027, and are categorized under NAICS code 541715.

Msts – DOE Contractor

POSTED

DEADLINE

ARTIFICIAL INTELLIGENCE AND NEXT GENERATION DISTRIBUTED COMMAND AND CONTROL

Solicitation # FA875023S7006

The Department of the Air Force, Air Force Materiel Command, AFRL Rome Research Site, is soliciting research and development for Artificial Intelligence and Next Generation Distributed Command and Control under BAA FA8750-23-S-7006. The primary objective is to transform Joint Force Command and Control capabilities by leveraging AI to enhance battlespace assessment, plan selection, and force monitoring in distributed and contested environments. A significant focus is placed on the Battle Management of AI, which seeks technologies to monitor, adapt, and deploy AI capabilities during mission execution to counter model drift and ensure operational safety. This is an open, two-step BAA effective until August 30, 2028, with total estimated funding of approximately $99 million. Individual awards typically range from $200,000 to $20 million and may be awarded as FAR-based procurement contracts, grants, cooperative agreements, or Other Transactions. Initial submissions are limited to three-page white papers, with formal proposals accepted by invitation only. Evaluation is based on a trade-off process considering overall scientific and technical merit, related experience, solution maturity and openness, and cost realism. Prospective offerors must adhere to strict guidelines, including the Gold Standard Science principles for reproducibility and transparency, and must disclose any potential Organizational Conflicts of Interest. Submissions require a CAGE code, unique entity identifier, and an approved DD Form 2345. The government may provide Government Furnished Software for specific technical areas, and all research must comply with National Industrial Security Program standards for the protection of classified information.

POSTED

DEADLINE

Systems for Phenotypic Evaluation, Clinical Trajectories, Response, and Agency (SPECTRA)

Solicitation # ARPA-H-SOL-26-163

The Systems for Phenotypic Evaluation, Clinical Trajectories, Response, and Agency (SPECTRA) program, issued by the Advanced Research Projects Agency for Health (ARPA-H) under solicitation ARPA-H-SOL-26-163, aims to advance the understanding and treatment of autism by identifying evolving developmental trajectories across the lifespan. The program focuses on the nonlinear interactions between genetic, biological, behavioral, and environmental factors to move toward personalized intervention. The scope of work is divided into four Technical Areas: Multi-Factor Analysis and Trajectory Identification (TA1), Population-Scale Modeling and Data Integration (TA2), Precision Intervention and Trajectory Testing (TA3), and Technologies for Communication, Quality of Life, and Embedded Assessment (TA4). Key deliverables include an operating federated network with at least ten live nodes, open-license data standards, a versioned model registry, and the development of technologies that combine clinical assessment with tools to improve daily function and quality of life. Awards will be made via Other Transaction (OT) instruments to proposers determined to be the most advantageous to the government based on scientific merit, capabilities, price/value analysis, and relevance to the ARPA-H mission. The program utilizes a milestone-based acceptance process with gates at 12, 24, and 48 months. Technical requirements emphasize privacy-preserving linkage, differential privacy, and secure execution. Proposers must be registered in SAM.gov and are required to use specific templates for Solution Summaries, with staggered submission deadlines ranging from October 2026 through January 2027. ARPA-H prioritizes entities that will conduct the funded work within the United States.

Advanced Research Projects Agency For Health (arpa-H)

POSTED

DEADLINE

Japanese Research PartnershipThe Japanese Research Partnership is a subcontract managed by the National Research Foundation of Korea to provide specialized research and facility support for prime contractors involved in International Joint Research Rapid Support Project optical interconnect projects. The scope of work focuses on collaborative research and development of uLED and uOLED technologies, utilizing the infrastructure of a recognized Japanese research institution to conduct joint experimentation and deliver shared data, research findings, and prototype contributions. The project is categorized under NAICS code 541715, with the place of performance located in South Korea. Interested parties should note that the solicitation was posted on October 29, 2026, with a response deadline of November 11, 2026.

National Research Foundation of Korea

POSTED

DEADLINE

2026년도 국제공동연구 신속지원사업 신규과제 공모

Solicitation # 2026-1045

The 2026 International Joint Research Rapid Support Project, solicitation number 2026-1045, is a government-funded initiative managed by the National Research Foundation of Korea and the Ministry of Science and ICT. The project focuses on developing core original technologies for high-density parallel light sources, specifically micro-LED and micro-OLED, for use in AI data center optical interconnects. The total government support funding is 737.5 million KRW for a 16-month performance period running from December 2026 to March 2028. This project is classified as a National Strategic Technology in the semiconductors and next-generation OLED sectors, aiming to advance from Technology Readiness Level 3 to TRL 5. A mandatory requirement for this solicitation is the establishment of an international joint research network with Japanese research institutions to secure expertise in organic light-emitting materials and patents. Technical objectives include developing 32-channel arrays with specific performance targets: transmission speeds exceeding 1 GHz for micro-LED and 0.2 GHz for micro-OLED, and driving energy levels of 1 pJ/bit and 20 pJ/bit respectively. Final acceptance requires the submission of a functional prototype and verification through accredited certification bodies, official test reports, or witnessed self-evaluations. All research achievements and commercialization results must be managed through the Integrated Research Information System (IRIS), and the project is subject to technology fee collection and the 3-book 5-public rule for concurrent research limits.

National Research Foundation of Korea

POSTED

DEADLINE

Transcriptomic & Epigenomic Assay Services

National Institutes Of Health

POSTED

DEADLINE

Genomic Sequencing Services (Whole-Genome & Long-Read)

National Institutes Of Health

POSTED

DEADLINE

Science, Technology & Innovation Data ProviderThis subcontract opportunity with the Government of Canada seeks a Science, Technology and Innovation Data Provider to support prime contractors on Public Services and Procurement Canada information product projects. The selected provider will be responsible for delivering technical datasets, innovation reports, patent data, technical specifications, and comprehensive R&D trend analysis. A critical requirement for this engagement is the provider's ability to enter into a Provider’s Master License Agreement. The project falls under NAICS code 541715 and will be performed within Canada. Interested parties must submit their responses by the deadline of March 31, 2027. This contract focuses on equipping prime contractors with the necessary technical data and innovation metrics to enhance the delivery of government information products.

Government of Canada / Gouvernement du Canada

POSTED

DEADLINE

Highway Safety Research & AnalysisThis subcontract opportunity involves providing specialized research and analysis for prime contractors working on South Dakota Department of Transportation highway safety projects. The primary objective is to evaluate flagger operations to identify safety gaps and establish effectiveness metrics. The selected provider will utilize traffic simulation software to generate data-driven operational recommendations and deliver comprehensive research reports and data analysis summaries. The project is managed under the South Dakota State Government with a response deadline of December 17, 2026. Classified under NAICS code 541715, the contract focuses on technical research and analysis to enhance highway safety protocols within the state.

South Dakota State Government

POSTED

1 day ago

DEADLINE

in about 2 months

AI Contract Overview

The final ISO for the RAPID program, issued by the Department of Health and Human Services' Advanced Research Projects Agency for Health (ARPA-H), aims to address the challenges faced by rare disease patients by developing innovative diagnostic tools through AI/ML for precision integrated diagnostics. The program seeks to end or significantly reduce the lengthy diagnostic processes that affect millions of patients worldwide by creating novel support tools for more efficient and accurate diagnosis on a population scale. The solicitation number for this initiative is ARPA-H-SOL-25-119, and it is listed under the NAICS code 541715 with a classification code of AN13. Key updates to the program include an extension of the proposal submission deadline to April 24, 2025, at 5:00 pm EDT, as specified in Amendment 1, which also updates all deadlines from EST to EDT. Additionally, due to uncontrollable circumstances, previously planned RAPID events, such as the Proposers’ Day and Patients’ Day, have been canceled, with information now being provided virtually if possible, including feedback expected by March 17-21, 2025. For further assistance, inquiries can be directed to the RAPID email box, with ongoing updates available on the RAPID Program Page. The opportunity remains active until May 9, 2025, and more details, including the full solicitation, can be accessed via the SAM.gov platform.

General Info

ISO for RAPID program develops AI/ML tools for rare disease diagnostics; submission deadline April 24, 2025.

Agency

Department Of Health And Human Services → NATIONAL INSTITUTES OF HEALTH

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

MD, USA

Set-Aside

NONE

Documents

ARPA-H-SOL-25-119 RAPID Amendment 1

amendment

High

ARPA-H-SOL-25-119 RAPID Innovative Solutions Opening

rfp

High

ARPA-H-SOL-25-119 RAPID Innovative Solutions Opening (Amendment 1)

65 pages · rfp

High

ARPA-H-SOL-25-119: Rare Disease AI/ML for Precision Integrated Diagnostics (RAPID)

rfp

High

ARPA-H Standard Cost Proposal Spreadsheet Template

specifications

High

ARPA-H Standard Cost Proposal Spreadsheet Template

43 pages · specifications

High

RAPID Rare Disease Prioritization Template

specifications

High

RAPID Rare Disease Prioritization Template

58 pages · specifications

High

RAPID Statement of Work Template

sow

High

RAPID Statement of Work Template

2 pages · sow

High

AI Contract Breakdown

Uniform Contract Format

Contract not broken down yet

CLEATUS splits the solicitation into Uniform Contract Format (UCF) sections: scope, pricing, deliverables, and evaluation criteria.

Timeline

PhaseClosed

PostedMar 14

Solicitation

Response DeadlineApr 24

Deadline has passed

Submission Closed

04/24/2025, 09:00:00 PM UTC

Find active opportunities like this

Get full access to discover similar active contracts, track opportunities, and build proposals with AI assistance.

Organization & Contact Information

AgencyDepartment Of Health And Human Services → NATIONAL INSTITUTES OF HEALTH

Contacts1 person available

OfficeBethesda, MD, 208920004, USA

Organization / AgencyDepartment Of Health And Human Services → NATIONAL INSTITUTES OF HEALTH

Office AddressBethesda, MD, 208920004, USA

Contacts

RAPID Box

contact@example.gov

Full Description

14 MAR: The deadline for proposals to the RAPID program (ARPA-H-SOL-25-119) is extended to April 24, 2025 05:00 pm EDT. Feedback on Solution Summaries is expected to be sent out the week of March 17-21, 2025.

Amendment 1 changes:

-The full proposal due date was extended to April 24, 2025

-All times were updated from EST to EDT

Visit the RAPID Program Page for additional materials and program updates.

21 FEB: The RAPID Patients’ Day (ARPA-H-SN-25-127) event is now CANCELLED. The RAPID team will post a video and other information when possible. Questions sent to contact@example.gov will be answered as soon as the RAPID team is able to respond.

23 JAN: Due to circumstances outside of ARPA-H’s control, the RAPID Proposers’ Day event is now CANCELLED. Questions sent to contact@example.gov ARE UNABLE TO BE ANSWERED AT THIS TIME.

22 JAN: RAPID proposers intending to participate in the RAPID Proposers' Day are encouraged to review ARPA-H Special Notice ARPA-H-SN-25-124. Due to circumstances outside of ARPA-H’s control, the RAPID Proposers’ Day event will now occur only virtually. Verified/accepted participants are encouraged to verify they have received the Zoom link/invitation. Questions sent to contact@example.gov will be addressed as quickly as possible.

The is the final ISO for the RAPID program. RAPID aims to end or significantly reduce the prolonged diagnostic odysseys affecting millions of rare disease patients worldwide. RAPID seeks to develop novel diagnostic support tools for population-scale rare disease detection, systematically identifying and diagnosing rare disease patients more efficiently and accurately.