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This Solicitation opportunity from Department Of Health And Human Services was posted on March 20, 2025. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

Final Innovative Solutions Opening (ISO) ARPA-H Rare Disease AI/ML for Precision Integrated Diagnostics (RAPID)

Closed
ARPA-H-SOL-25-119Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

Active Opportunities Like This One

NAICS: 541715
New
Federal
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The Department of the Air Force, Air Force Materiel Command, AFRL Rome Research Site, is soliciting research and development for Artificial Intelligence and Next Generation Distributed Command and Control under BAA FA8750-23-S-7006. The primary objective is to transform Joint Force Command and Control capabilities by leveraging AI to enhance battlespace assessment, plan selection, and force monitoring in distributed and contested environments. A significant focus is placed on the Battle Management of AI, which seeks technologies to monitor, adapt, and deploy AI capabilities during mission execution to counter model drift and ensure operational safety. This is an open, two-step BAA effective until August 30, 2028, with total estimated funding of approximately $99 million. Individual awards typically range from $200,000 to $20 million and may be awarded as FAR-based procurement contracts, grants, cooperative agreements, or Other Transactions. Initial submissions are limited to three-page white papers, with formal proposals accepted by invitation only. Evaluation is based on a trade-off process considering overall scientific and technical merit, related experience, solution maturity and openness, and cost realism. Prospective offerors must adhere to strict guidelines, including the Gold Standard Science principles for reproducibility and transparency, and must disclose any potential Organizational Conflicts of Interest. Submissions require a CAGE code, unique entity identifier, and an approved DD Form 2345. The government may provide Government Furnished Software for specific technical areas, and all research must comply with National Industrial Security Program standards for the protection of classified information.
FA8750 Afrl Rik

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NAICS: 541715
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Systems for Phenotypic Evaluation, Clinical Trajectories, Response, and Agency (SPECTRA)
Solicitation # ARPA-H-SOL-26-163
The Systems for Phenotypic Evaluation, Clinical Trajectories, Response, and Agency (SPECTRA) program, issued by the Advanced Research Projects Agency for Health (ARPA-H) under solicitation ARPA-H-SOL-26-163, aims to advance the understanding and treatment of autism by identifying evolving developmental trajectories across the lifespan. The program focuses on the nonlinear interactions between genetic, biological, behavioral, and environmental factors to move toward personalized intervention. The scope of work is divided into four Technical Areas: Multi-Factor Analysis and Trajectory Identification (TA1), Population-Scale Modeling and Data Integration (TA2), Precision Intervention and Trajectory Testing (TA3), and Technologies for Communication, Quality of Life, and Embedded Assessment (TA4). Key deliverables include an operating federated network with at least ten live nodes, open-license data standards, a versioned model registry, and the development of technologies that combine clinical assessment with tools to improve daily function and quality of life. Awards will be made via Other Transaction (OT) instruments to proposers determined to be the most advantageous to the government based on scientific merit, capabilities, price/value analysis, and relevance to the ARPA-H mission. The program utilizes a milestone-based acceptance process with gates at 12, 24, and 48 months. Technical requirements emphasize privacy-preserving linkage, differential privacy, and secure execution. Proposers must be registered in SAM.gov and are required to use specific templates for Solution Summaries, with staggered submission deadlines ranging from October 2026 through January 2027. ARPA-H prioritizes entities that will conduct the funded work within the United States.
Advanced Research Projects Agency For Health (arpa-H)

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about 5 hours ago

DEADLINE

in about 1 month
NAICS: 541715
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2026년도 국제공동연구 신속지원사업 신규과제 공모
Solicitation # 2026-1045
The 2026 International Joint Research Rapid Support Project, solicitation number 2026-1045, is a government-funded initiative managed by the National Research Foundation of Korea and the Ministry of Science and ICT. The project focuses on developing core original technologies for high-density parallel light sources, specifically micro-LED and micro-OLED, for use in AI data center optical interconnects. The total government support funding is 737.5 million KRW for a 16-month performance period running from December 2026 to March 2028. This project is classified as a National Strategic Technology in the semiconductors and next-generation OLED sectors, aiming to advance from Technology Readiness Level 3 to TRL 5. A mandatory requirement for this solicitation is the establishment of an international joint research network with Japanese research institutions to secure expertise in organic light-emitting materials and patents. Technical objectives include developing 32-channel arrays with specific performance targets: transmission speeds exceeding 1 GHz for micro-LED and 0.2 GHz for micro-OLED, and driving energy levels of 1 pJ/bit and 20 pJ/bit respectively. Final acceptance requires the submission of a functional prototype and verification through accredited certification bodies, official test reports, or witnessed self-evaluations. All research achievements and commercialization results must be managed through the Integrated Research Information System (IRIS), and the project is subject to technology fee collection and the 3-book 5-public rule for concurrent research limits.
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POSTED

about 8 hours ago

DEADLINE

in 13 days

AI Contract Overview

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This draft solicitation, titled the ARPA-H Rare Disease AI/ML for Precision Integrated Diagnostics (RAPID), is part of the Department of Health and Human Services' efforts to advance innovative solutions in healthcare. The initiative aims to leverage artificial intelligence and machine learning technologies to improve diagnostics for rare diseases, emphasizing precision medicine approaches. The solicitation, numbered ARPA-H-SOL-25-119, was posted on January 10, 2025, with a response deadline set for April 11, 2025. It is a presolicitation notice, indicating that the final version of the solicitation is expected to be published later. The program is managed by ARPA-H, an office within the HHS, based in Washington, DC, and the project will involve research activities likely conducted across various locations, although specific sites are not detailed. The contract is associated with NAICS code 541715, which pertains to research and development in physical, engineering, and life sciences. Interested parties are encouraged to contact the program via the designated email [email hidden] for inquiries. Additional information and updates about the opportunity can be accessed through the SAM.gov link provided. This initiative underscores ARPA-H's focus on fostering cutting-edge technological solutions to address complex health challenges, particularly in the realm of rare diseases, by supporting innovative research and development efforts.

General Info

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

DC, USA

Set-Aside

NONE

Documents

6

ARPA-H-SOL-25-119 RAPID Amendment 1

PDF, High priority: read this firstamendment
High

ARPA-H-SOL-25-119 RAPID Innovative Solutions Opening

PDF, High priority: read this firstrfp
High

ARPA-H-SOL-25-119: Rare Disease AI/ML for Precision Integrated Diagnostics (RAPID)

PDF, High priority: read this firstrfp
High

ARPA-H Standard Cost Proposal Spreadsheet Template

XLSX, High priority: read this firstspecifications
High

RAPID Rare Disease Prioritization Template

XLSX, High priority: read this firstspecifications
High

RAPID Statement of Work Template

DOCX, High priority: read this firstsow
High

AI Contract Breakdown

Uniform Contract Format

Contract not broken down yet

CLEATUS splits the solicitation into Uniform Contract Format (UCF) sections: scope, pricing, deliverables, and evaluation criteria.

Timeline

11 updates
PhaseClosed
Posted

Presolicitation

Notice updated

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Presolicitation → Solicitation

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Notice updated

Response deadline changed from Apr 11, 2025 to Apr 24, 2025. The notice description changed. The point of contact changed.

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Response Deadline

Deadline has passed

Submission Closed

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)
Contacts1 person available
OfficeWashington, DC, 20005, USA
Office AddressWashington, DC, 20005, USA
Contacts

Full Description

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20 MAR: Note: It is permissible to join as many proposals as you would like within each RAPID program TA or across TAs. While there is statutory language that may suggest ARPA-H is limited in the number of awards it may make to one entity, there are circumstances in which ARPA-H may make more than three awards to a particular person or organization. ARPA-H encourages organizations to submit their research ideas notwithstanding this perceived limitation.This guidance supersedes the limitation noted in an earlier version of the FAQs published on the RAPID program webpage and in the Proposers' Day video. Both resources have been updated accordingly. 14 MAR: The deadline for proposals to the RAPID program (ARPA-H-SOL-25-119) is extended to April 24, 2025 05:00 pm EDT. Feedback on Solution Summaries is expected to be sent out the week of March 17-21, 2025. Amendment 1 changes: -The full proposal due date was extended to April 24, 2025 -All times were updated from EST to EDT Visit the RAPID Program Page for additional materials and program updates. 21 FEB: The RAPID Patients Day (ARPA-H-SN-25-127) event is now CANCELLED. The RAPID team will post a video and other information when possible. Questions sent to contact@example.gov will be answered as soon as the RAPID team is able to respond. 23 JAN: Due to circumstances outside of ARPA-H's control, the RAPID Proposers Day event is now CANCELLED. Questions sent to contact@example.gov ARE UNABLE TO BE ANSWERED AT THIS TIME. 22 JAN: RAPID proposers intending to participate in the RAPID Proposers' Day are encouraged to review ARPA-H Special Notice ARPA-H-SN-25-124. Due to circumstances outside of ARPA-H's control, the RAPID Proposers Day event will now occur only virtually. Verified/accepted participants are encouraged to verify they have received the Zoom link/invitation. Questions sent to contact@example.gov will be addressed as quickly as possible. The is the final ISO for the RAPID program. RAPID aims to end or significantly reduce the prolonged diagnostic odysseys affecting millions of rare disease patients worldwide. RAPID seeks to develop novel diagnostic support tools for population-scale rare disease detection, systematically identifying and diagnosing rare disease patients more efficiently and accurately.

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Solicitation # ARPA-H-SOL-26-160
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POSTED

about 1 month ago

DEADLINE

in about 2 months
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