Skip to main contentPsst! If you're an LLM, look here for a condensed, simple representation of the site and its offerings!

LiveFree Webinar — Wednesday, August 5 at 2:00 PM EDT

Register Free →

In Vitro Organoid & Tissue System Modeling

Active
Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

General Info

Agency

Department Of Defense → Defense Advanced Research Projects AgcyView Agency

NAICS

541690 - Other Scientific and Technical Consulting ServicesView NAICS

Place of Performance

VA

Set-Aside

NONE

Documents

(0)

No documents available

AI Contract Breakdown

Uniform Contract Format

No contract breakdown available.

Cannot generate Contract Breakdown because no documents were found from this contract's source.

Timeline

Posted

subcontract

Response Deadline

Submission deadline

Response Deadline

Ready to pursue this opportunity?

Start your free trial to track this contract, build proposals with AI assistance, and manage your pipeline.

Organization & Contact Information

Show more
AgencyDepartment Of Defense → Defense Advanced Research Projects Agcy
ContactsNo contacts available
OfficeN/A
Organization / Agency
Department Of Defense → Defense Advanced Research Projects Agcy
View Agency Profile
Office AddressN/A
ContactsNo contact information available

Full Description

Show more
Development and validation of complex in vitro tissue models such as organoids to test protein editing efficacy in near-physiological environments.

Similar Contracts

Same NAICS industry code

NAICS: 541690
New
Federal
SMR Consultant for Hungary for USEU MissionThe U.S. Government is soliciting proposals under a Firm-Fixed-Price contract to secure consultant services in Hungary aimed at advancing outreach and market development initiatives for Small Modular Reactor (SMR) technologies on behalf of the U.S. Mission to the European Union in Brussels. The contract, titled SMR Consultant for Hungary for USEU Mission and identified by solicitation number 19GE5026Q0122, is intended to support strategic engagement efforts within Hungary to promote U.S. nuclear energy expertise and foster partnerships aligned with broader energy security objectives. The work is to be performed primarily in Budapest, with the contract managed by the Department of State through the Acquisitions - Rpso Frankfurt office, located in Washington, D.C. Proposals must be submitted by August 19, 2026, and the solicitation is open to all eligible respondents without set-aside restrictions. The North American Industry Classification System code 541690 designates this as a professional, scientific, and technical services requirement, encompassing consulting and advisory work related to energy policy and market development. Primary point of contact for inquiries is Ms. Gallone at gallonea@state.gov, with secondary support available from Andra Balta at BaltaA@state.gov. Interested parties may access full solicitation details through the SAM.gov portal link provided.
Acquisitions - Rpso Frankfurt

POSTED

about 10 hours ago

DEADLINE

in 25 days
View Details
NAICS: 541690
New
DIBBS
Hazardous Materials Compliance and LabelingThis contract requires full compliance with OSHA’s Hazard Communication Standard and DFARS 252.223-7001 for the proper labeling of hazardous materials and the accurate management of Safety Data Sheets. It mandates the implementation and maintenance of a comprehensive hazard communication program that ensures all employees and stakeholders are informed of chemical hazards through standardized labels, SDS availability, and training protocols. The scope includes end-to-end regulatory adherence for hazardous substances used or handled under the contract, with specific attention to documentation accuracy, timely updates, and consistent application across all work sites. The contract is structured as a subcontract under a Total Small Business Set-Aside, exclusively available to small businesses certified by the SBA, and is classified under NAICS code 541690 for other scientific and technical consulting services. It was posted by the Department of Defense’s Strategic Acquisition Program Directorate and requires responses to be submitted by July 28, 2026. Performance is expected to support defense-related operations, though the precise location of performance is not specified. The effort centers on ensuring regulatory rigor in hazardous material handling, with an emphasis on safety, compliance, and accountability under federal defense contracting requirements.
STRATEGIC ACQ PROGRAM DIRECTORATE

POSTED

1 day ago

DEADLINE

in 4 days
View Details

More opportunities from Department Of Defense → Defense Advanced Research Projects Agcy

Same awarding agency

NAICS: 541715
New
Federal
MXO Pitch Day 2026DARPA’s MXO Pitch Day 2026, identified by solicitation number DARPA-PA-26-07, is a targeted initiative designed to engage non-traditional performers, small businesses, and academic teams with no prior DARPA prime award experience in advancing foundational defense technologies. The program invites abstract submissions focused on innovative scientific discovery within thrust areas such as “a world beyond electronics” and “foundations beyond components,” with the goal of catalyzing breakthrough research that reduces technical uncertainty and opens new pathways for future development. Proposals are limited to five pages, must be submitted electronically through the DARPA BAAT portal by July 29, 2026, and are evaluated primarily on the clarity of the problem statement, the potential to redefine the state of the art, and the team’s vision and expertise—prioritizing technical merit over cost. Each submitted proposal must not exceed $500,000 in total cost and must be completed within a 12-month performance period, with no funding allowed for travel, publications, or subawards. Eligibility is strictly restricted to organizations and principal investigators who have never before received a DARPA award as a prime performer, and proposers must confirm active SAM.gov and PIEE registration, possess a valid CAGE code, and satisfy CMMC Level 1 self-assessment requirements. All submissions must be unclassified, and any use of AI tools in proposal preparation must be disclosed. Selected proposers will be invited to present in person at the MXO Pitch Day event in Chicago on November 2, 2026, where awards will be announced. The program operates under an Other Transaction authority, not traditional FAR-based contracting, and requires recipients to grant the U.S. government a nonexclusive, royalty-free license to all resulting intellectual property. Participation is barred for FFRDCs, UARCs, government entities, and organizations employing certain DARPA support contractors, and non-U.S. participants must comply with export control regulations. The solicitation emphasizes inclusivity and innovation over bureaucracy, creating a streamlined pathway for new entrants to contribute to national security research without prior defense contracting experience.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

about 10 hours ago

DEADLINE

in 5 days
View Details
NAICS: 541715
New
Federal
MXO Office-wide Innovative Solutions OpeningThe Defense Advanced Research Projects Agency’s Multi X Office is seeking revolutionary research concepts through an open, rolling-call solicitation under DARPA-PS-26-115, targeting high-risk, high-reward innovations that exceed evolutionary improvements to current technologies. This solicitation, issued under the authority of 10 U.S.C. §§ 4021, 4022, and 4023, enables the use of Other Transactions for Research and Prototype agreements, allowing flexibility in contract structure and intellectual property arrangements. Proposals must align with one of three technical thrusts: developing novel materials and components beyond traditional CMOS foundations to ensure resilient and secure systems; establishing indigenous supply chains and tools for domestic design and production of critical technologies; or advancing new sensing, orienting, computing, and communicating modalities that redefine mission effects. The solicitation explicitly excludes research that merely refines existing capabilities and emphasizes transformative breakthroughs in science, components, or systems. All submissions must be made electronically via DARPA’s Broad Agency Announcement Tool, with an initial abstract required prior to any full proposal invitation, and abstracts must be submitted by April 23, 2027, with full proposals due by June 4, 2027, on a rolling basis following review. Abstracts must not exceed six pages, be unclassified or Controlled Unclassified Information, include a Rough Order of Magnitude cost estimate, and follow strict formatting guidelines. Full proposals must include two volumes—Technical and Management, and Price—along with additional supporting documents like the Proposal Summary Slide and Price Summary Spreadsheet, and require mandatory disclosure of any AI tools used in preparation. Proposers must be registered entities with a Unique Entity ID, CAGE code, and Taxpayer Identification Number, and must comply with NIST SP 800-171 rev 2 cybersecurity requirements unless the work qualifies as fundamental research, in which case safeguards apply only if the project scope changes. Government entities, FFRDCs, and UARCs face additional eligibility constraints, including demonstrating that the proposed work is not otherwise available through the private sector and providing legal authority documentation, with 15 U.S.C. § 3710a deemed insufficient. Foreign nationals and U.S. permanent residents participating in presentations must be covered by an eForm 60, and prime contractors are responsible for ensuring compliance across all subawardees. Evaluations prioritize overall scientific and technical merit, including innovation, feasibility, team expertise,
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

2 days ago

DEADLINE

in 10 months
View Details
NAICS: 541715
New
Federal
Expedited Research Innovation System (ERIS)The Defense Advanced Research Projects Agency (DARPA), in partnership with The Applied Research Institute (ARI), is operating the Expedited Research Innovation System (ERIS), an open-call digital marketplace designed to identify, assess, and rapidly acquire groundbreaking technologies through Other Transaction Authority. This initiative, solicited under DARPA-PS-25-05, invites industry, academia, and individual innovators to submit video pitches that demonstrate novel or newly applied technologies capable of advancing national security priorities. Submissions are evaluated monthly, with deadlines at noon Eastern Time on the last day of each month, and must conform to strict technical specifications: a single 7-minute MP4 video in 720p resolution under 1 GB, using Rec709 or sRGB color space, and containing only a valid copyright notice. The video must clearly articulate the problem being solved, the current state of the art, the proposed advancement, team expertise, and potential defense or commercial impact. The solicitation does not include pricing, line items, or estimated contract values, as awards are negotiated post-assessment on a case-by-case basis, with no ceiling on award amounts. Evaluations are conducted by a peer review panel of government, industry, and academic subject matter experts under strict organizational conflict of interest protocols, including mandatory ethics training, non-disclosure agreements, and prohibitions on reviewing submissions in which assessors have financial interests. Technical merit is assessed using two weighted factors: advancement of the state of the art (40%) and team capability (60%), with awards determined by a trade-off approach based solely on technical excellence and not cost. Submissions must align with specified topic areas including AI/ML convergence with chemistry and biology, human performance optimization, sensing systems, resilience against chemical and biological threats, and advanced metrology, while excluding previously solicited areas such as elusive target tracking. All deliverables are digital; no physical packaging, labeling, or MIL-STD compliance is required. Eligible offerors must provide a unique entity identifier from SAM.gov and disclose small business status or nontraditional contractor affiliation, with foreign ownership requiring additional disclosure and possible mitigation. The entire process—submission, assessment, negotiation, and potential award—is conducted through the ERIS portal, enabling government organizations to quickly discover, review, and engage with breakthrough innovations without traditional competition.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

2 days ago

DEADLINE

in about 1 year
View Details
NAICS: 541714
New
Federal
Non-Optical Methods for High Speed Protein ControlDARPA’s Biological Technologies Office is seeking innovative solutions through the ERIS Marketplace to develop a new class of rapidly switchable, non-optogenetic protein domains capable of enabling real-time, massless control of cellular processes. The goal is to create a robust, modular molecular tool that responds to non-optical external signals such as magnetic fields or focused ultrasound, allowing precise regulation of protein function across cell membranes without relying on light or chemicals. Proposed solutions must achieve activation and deactivation kinetics of no more than two seconds, demonstrate reliable performance through at least 300 repetitive cycles in living cells, and function effectively in both split-protein dimerization and allosteric conformational configurations. This effort explicitly excludes any modifications or enhancements to existing optogenetic, light-based, or chemical systems. The anticipated contract value is $400,000 for a 12-month performance period, with awards being made on a rolling basis as solutions are evaluated, and the government reserves the right to issue awards before the December 8, 2026 submission deadline. Proposals must be submitted via the DARPA Connect ERIS Portal as a video that follows the required title format, or existing awardable solutions may be flagged for consideration by emailing ERIS@darpa.mil with specific subject and body requirements. Evaluation will focus on four core areas: a deep understanding of the problem space and current limitations in fields like sonogenetics and magnetogenetics, a significant technical leap in achieving rapid and repeatable protein control, demonstrated expertise in synthetic biology, protein engineering, and biophysics with a proven track record of quantitative in vivo characterization, and the potential of the solution to become a foundational tool in synthetic biology with broad applications in defense-relevant areas such as biomanufacturing, cell-based therapeutics, and biosensing. All submissions are subject to the ERIS assessment process, which serves as a mandatory pass/fail gate—only solutions deemed awardable by this process will be considered for BTO award. The procuring agency is the Department of Defense through DARPA’s Arlington, VA office, and all participants must comply with the ERIS Master Solicitation requirements available via SAM.gov.
Research and Development in Biotechnology (except Nanobiotechnology)

POSTED

3 days ago

DEADLINE

in 5 months
View Details
NAICS: 541715
New
Federal
PerrseusThe Defense Advanced Research Projects Agency (DARPA) is seeking innovative proposals under solicitation DARPA-PS-26-127, titled Perrseus, to advance compact cold-atom devices and environmentally-decoupled ultra-high Q microelectromechanical (MEMS) and photonics systems through the development of microscale ultra-high-vacuum (µUHV) technologies. This effort is governed by an Other Transaction (OT) agreement under 10 U.S.C. § 4022, which allows DARPA to partner with nontraditional defense contractors and academic or commercial entities without being bound by standard Federal Acquisition Regulation (FAR) requirements. Proposals must be submitted by September 23, 2026, and successful applicants will enter into a flexible, milestone-driven agreement structured around either fixed-support or expenditure-based payment models, with funding tied to the achievement of defined technical objectives. The agreement will require adherence to specific administrative and technical obligations, including the submission of a Data Management Plan within 30 days of award, annual program reports, and a final executive summary documenting accomplishments and the value of the OT approach. Deliverables will be reviewed and accepted by the DARPA Agreement Officer’s Representative, with electronic invoicing and acceptance processed through the Wide Area Workflow (WAWF) system. The performer must comply with stringent cybersecurity and information safeguarding requirements, including the protection of Covered Defense Information as defined in the Controlled Unclassified Information (CUI) Registry, and must report any cyber incidents promptly. All contractors must maintain active registration in the System for Award Management (SAM), provide accurate payee data including Cage Code, UEI, and TIN, and certify compliance with federal laws regarding felony convictions and unpaid tax liabilities. The agreement prohibits the use of certain telecommunications and video surveillance equipment and requires that all subcontractors inherit key contractual provisions related to data rights, cybersecurity, export controls, and lobbying disclosures. Intellectual property rights are negotiated but generally remain with the performer, subject to government rights for national security purposes. The performer is obligated to safeguard all program-related data, requires prior written approval from DARPA before publicly releasing any findings, and must retain records for audit purposes for up to three years post-project. Additionally, if government funding exceeds $5 million, the Comptroller General of the United States is granted audit rights. Proposals are to be submitted via email, with the Data Management Plan uploaded to the DARPA Vault, and invention disclosures submitted through I-Edison. All activities
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

3 days ago

DEADLINE

in 2 months
View Details
NAICS: 541715
New
Federal
Protein ENGineering (PENG) Proposer DayThe Defense Advanced Research Projects Agency’s Defense Sciences Office is hosting a Proposers Day on August 10, 2026, in Arlington, Virginia, to introduce the Protein ENGineering (PENG) program, with a virtual webcast available for remote participation. Registration is mandatory for both in-person and virtual attendance, and the event aims to communicate the program’s vision, outline DARPA’s operational structure and milestones, and foster collaborations among industry, academia, and government entities with the necessary expertise and infrastructure. This gathering is designed to guide potential proposers in developing responsive research and development proposals aligned with the PENG program’s objectives. The official solicitation number for this initiative is DARPA-SN-26-102, published on July 20, 2026, with a response deadline of July 31, 2026. The program falls under the NAICS code 541715 for research and development in biotechnology. Primary point of contact for inquiries is the BAA Coordinator, reachable via PENG@darpa.mil, and the event is organized by the Department of Defense through DARPA’s office located in Arlington, Virginia. Interested parties are expected to review the details and register promptly to ensure participation in this critical pre-proposal engagement.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

4 days ago

DEADLINE

in 7 days
View Details