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Investigate Novel Therapeutic Interventions and Testing Strategies for Neurological Disorders Including to Treat, Modify and Prevent the Development of Epilepsy (U24 Clinical Trial Not Allowed)

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Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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The National Institute of Neurological Disorders and Stroke (NINDS) plans to issue a Notice of Funding Opportunity aimed at supporting research focused on novel therapeutic interventions and testing strategies for neurological disorders, with an emphasis on epilepsy. The initiative seeks applications that explore various modalities to treat, modify, and prevent the development of epilepsy through innovative approaches. Researchers are encouraged to develop and validate human-focused testing strategies, as well as contribute expertise in preclinical therapy testing and model development. This funding opportunity does not allow clinical trials under the U24 mechanism and emphasizes preclinical and translational research efforts. The solicitation encourages multidisciplinary approaches to advance therapeutic development for neurological conditions, particularly epilepsy. Interested investigators are advised to contact Brian Klein, PhD, at the National Institutes of Health for further information. The announcement was posted in late September 2025 by the Department of Health and Human Services.

General Info

NINDS invites preclinical research applications for innovative epilepsy therapies and testing strategies.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) View NAICS

Place of Performance

Not specified

Set-Aside

NONE

Documents

(0)

No documents available

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Timeline

Posted

forecast

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUS
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health
Office AddressUS
Contacts
Brian Klein PhD
contact@example.gov
+1 (555) 000-0000

Full Description

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The National Institute of Neurological Disorders and Stroke (NINDS) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications to investigate novel therapeutic interventions and testing strategies for neurological disorders including to treat, modify, and prevent epilepsy. This research should include various intervention modalities and testing strategies. Investigators should consider testing strategies for the development and validation of human-focused testing approaches. Investigators with expertise and insights into preclinical therapy testing and model development are encouraged to consider applying for this new NOFO. 

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