This Solicitation opportunity from Department Of Health And Human Services was posted on July 31, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Medicinal Chemistry Support for Therapeutic Development: Synthesis of HERV-K Protease Inhibitors

Closed

75N98026Q00906Federal

Submission Closed08/10/2026, 01:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541380

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AI Contract Overview

The National Institutes of Health is seeking commercial offerings for the synthesis of HERV-K protease inhibitors as part of medicinal chemistry support for therapeutic development, under solicitation number 75N98026Q00906. This is a competitive, firm-fixed-price acquisition conducted under FAR Subpart 12.6 as a streamlined solicitation for commercial items, with a projected value not exceeding $350,000. The government intends to award the contract to the offeror providing the best value based on technical capability, price, past performance, and delivery schedule. The work involves the design and synthesis of inhibitors targeting HERV-K protease, and responses must include full pricing details, delivery terms, F.O.B. point, product identifiers, and a clear timeline for completion after award. All offerors must be active in SAM.gov and provide their Unique Entity Identifier, Taxpayer Identification Number, and business size certification. The requirement is not set aside for small businesses, and the associated NAICS code is 541380. Proposals must be submitted electronically by August 10, 2026, at 9:00 AM Eastern Time to James Law at [email hidden] and must include the completed FAR 52.212-3 representations and certifications. The contract will be formed automatically upon written notice of award if submitted within the specified timeframe. Additional evaluation criteria may consider warranty, lifecycle costs, maintenance availability, and environmental efficiency. The place of performance is Bethesda, Maryland, and all terms and conditions are governed by FAR 52.212-4 and 52.212-5, incorporating applicable statutory and executive order requirements. Offerors are expected to demonstrate proven ability in medicinal chemistry, particularly in organic synthesis and protease inhibitor development, with the capability to deliver high-quality compounds on schedule.

General Info

NIH seeks commercial synthesis of HERV-K protease inhibitors under $350,000 firm-fixed-price contract with technical and pricing evaluation.

Agency

Department Of Health And Human Services → National Institutes Of Health Olao

NAICS

541380 - Testing Laboratories and Services

Place of Performance

Bethesda, MD, 20892, USA

Set-Aside

NONE

Documents

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Timeline

PhaseClosed

PostedJul 31

Solicitation

Response DeadlineAug 10

Deadline has passed

Submission Closed

08/10/2026, 01:00:00 PM UTC

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Organization & Contact Information

AgencyDepartment Of Health And Human Services → National Institutes Of Health Olao

Contacts1 person available

OfficeBETHESDA, MD, 20892, USA

Organization / AgencyDepartment Of Health And Human Services → National Institutes Of Health Olao

Office AddressBETHESDA, MD, 20892, USA

Contacts

LAW JAMES B

contact@example.gov

Full Description

COMBINED SYNOPSIS / SOLICITATION

Title: Medicinal Chemistry Support for Therapeutic Development: Synthesis of HERV-K Protease Inhibitors

This is a combined synopsis/solicitation for commercial items prepared in accordance with FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested, and a separate written solicitation will not be issued.

The solicitation number is 75N98026Q00906. This solicitation is issued as a competitive combined synopsis/solicitation for commercial products or commercial services. The Government intends to award a contract or purchase order resulting from this solicitation using full and open competition.

This acquisition is conducted under the authority of FAR 12.603, Streamlined Solicitation for Commercial Products or Commercial Services, and is not expected to exceed the simplified acquisition threshold of $350,000.00.

The National Institutes of Health (NIH), Office of the Director, Office of Acquisitions, seeks to award a Firm-Fixed-Price to the responsible offeror whose proposal represents the best value to the Government.

The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2026-01 March 13, 2026.

The associated NAICS code is 541380, and the small business size standard is N/A.

This requirement is NOT A SET-ASIDE for small businesses.

Description of Requirement:

Medicinal Chemistry

The provision at FAR 52.212-1, Instructions to Offerors—Commercial Items, applies to this acquisition. Add any agency-specific instructions as required.

The provision at FAR 52.212-2, Evaluation—Commercial Items, applies to this acquisition.

The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation represents the best value to the Government, price and other factors considered.

Evaluation Factors:

Technical capability
Price
Past performance
Delivery schedule

A written notice of award or acceptance of an offer, issued within the time specified in the offer, shall result in a binding contract without further action by either party. The Government reserves the right to accept any offer before the expiration date.

Offerors shall include a completed copy of FAR 52.212-3, Offeror Representations and Certifications—Commercial Items, with their offer.

FAR 52.212-4, Contract Terms and Conditions—Commercial Items, applies to this acquisition.

FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders—Commercial Items, applies to this acquisition.

Submission Requirements:
Responses must include sufficient information to demonstrate the offeror’s capability to provide the required product or service. Quotes shall include, at a minimum:

Unit and total price
Shipping and handling costs
Delivery timeframe after award
Delivery terms
F.O.B. point (destination)
Product or catalog numbers (if applicable)
Product/service description

Additional evaluation considerations may include past performance, warranty, lifecycle cost, maintenance availability, and environmental or energy efficiency.

Responses must include the Unique Entity Identifier (UEI), Taxpayer Identification Number (TIN), and business size certification. All offerors must be actively registered in the System for Award Management (SAM) at www.sam.gov.

All responses must be received by August 10, 2026 at 9:00 AM and must reference solicitation number 75N98026Q00906. Responses may be submitted electronically to contact@example.gov.

Point of Contact:
James Law

contact@example.gov