Molecular Dynamics Simulation Software Platform Development

The contract seeks the development and delivery of a molecular modeling simulation platform with integrated artificial intelligence and machine learning capabilities to enable atomic-level analysis of protein-excipient interactions, drug-nanomaterial dynamics, and biologics stability. The platform must deliver high-fidelity molecular dynamics simulations capable of capturing complex molecular behaviors with computational precision and predictive accuracy, supporting pharmaceutical research and biologics formulation development. The technology is expected to integrate advanced AI/ML models trained on experimental and simulation data to accelerate insights into molecular interactions that influence drug efficacy, delivery, and shelf life. The contract is designated as a subcontract under NAICS code 511210, issued by the Omas Strategic Buying Center - Information Technology within the Department of Health and Human Services. The place of performance is specified as Silver Spring, Maryland, with a response deadline of July 1, 2026, at 7:30 PM Eastern Time. The solicitation was posted on June 24, 2026, and is open for submissions through the SAM.gov portal, though no specific set-aside classification or point of contact details are provided. The project requires a technically robust solution that bridges computational biophysics with applied machine learning to address critical challenges in drug development and biologics manufacturing.