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Notice of Intent to Increase the Ceiling on N66001-14-C-4016

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N66001_SNOTE_000D790EFederal

Contract Overview

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The contract involves an increase to the funding ceiling for Contract N66001-14-C-4016 awarded to Wake Forest University Health Sciences by SSC Pacific on behalf of DARPA's Defense Sciences Office. Originally initiated in January 2014 for a six-month period, the project builds on the REMIND program by applying a memory prosthesis device, previously developed for nonhuman primates, to human patients undergoing surgery for brain conditions like epilepsy. This contract supports research demonstrating the successful use of direct neural interfaces to encode specific neural signals that enhance memory formation and recall in humans, marking a significant advancement in neurotechnology aligned with the objectives of the BRAIN Initiative. The additional funding of approximately $4.9 million will expand the scope of work to validate the initial findings with more human subjects, assess the precision of neural stimulation in facilitating memory for specific object categories, and explore the transferability of these neural codes across different individuals. Due to the innovative and exploratory nature of this research, DARPA acknowledges that the outcomes could not have been previously predicted. This notice of intent is not a solicitation for competitive bids and will be open for public comment for 15 days, with the Government reserving the sole discretion to decide on competition. Interested parties may submit comments to the designated Contract Specialist at SPAWAR Systems Center Pacific.

General Info

Funding increase for neurotechnology research applying memory prosthesis to human epilepsy patients.

Agency

Department Of Defense → Niwc Pacific

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

Set-Aside

NONE

Documents

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Timeline

PostedSep 28

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Organization & Contact Information

AgencyDepartment Of Defense → Niwc Pacific

ContactsNo contacts available

OfficeSAN DIEGO, CA, 92152-5001, USA

Organization / AgencyDepartment Of Defense → Niwc Pacific

Office AddressSAN DIEGO, CA, 92152-5001, USA

ContactsNo contact information available

Full Description

This is a notice of intent to increase the ceiling of Contract N66001-14-C-4016 to Wake Forest University Health Sciences, awarded by SSC Pacific on behalf of the Defense Advanced Research Projects Agency Defense Sciences Office (DARPA/DSO) on 31 January 2014 for a performance period of six (6) months. This effort extrapolated the achievements of the REMIND program to circumstances that facilitated application of the memory prosthesis device developed for nonhuman primates (NHPs), to human patients undergoing surgery for brain disease conditions such as epilepsy in order to restore retention of item specific information necessary for cognitive function. The Wake Forest team has demonstrated for the first time that a direct neural interface could be used to write in specific neural codes into the brain to facilitate memory formation and recall in human subjects. This groundbreaking discovery is advancing DARPAs neurotechnology portfolio in support of President Obamas BRAIN Initiative. This additional effort seeks to add tasking to this effort with these specific aims: 1) extend their findings to additional human patients in order to validate these results, 2) test the specificity of memory facilitation using neural stimulation codes that correspond to specific object categories and features, and 3) test the generalizability and transferability of these memory codes across humans. The NAICS code for this procurement is 541712. Due to the nature of Research and Development efforts, DARPA could not have reasonably estimated the results of the research from this program, which has seen breakthroughs that will benefit from continued research under this current contract. This action includes a ceiling increase of approximately $4,900,000. This notice of intent is not a request for competitive proposals or quotes and will be posted for 15 days. A determination by the Government not to compete based upon response to this notice is solely within the discretion of the Government. Interested parties may submit comments in writing to the Contract Specialist, Ms. Megan Ashley, Code 22530, SPAWAR Systems Center Pacific who may be reached by telephone at +1 (555) 000-0000 or via email to contact@example.gov.

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