This Combined Synopsis/Solicitation opportunity from Department Of Health And Human Services was posted on August 11, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Notice of Intent to Sole Source: West Virginia University Research Corporation

Awarded

98769Federal

Submission Closed08/21/2026, 04:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541714

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High-throughput Unmasking of Biological Interactomes with Binding Landscape Emulators (HUBBLE)

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Defense Health Agency

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RFI Alzheimer’s Research Program (AZRP) Public

Solicitation # HT9427RFI2027AZRP

The Defense Health Agency, through the Congressionally Directed Medical Research Programs, has issued a Request for Information under solicitation number HT9427RFI2027AZRP to gather strategic feedback for the fiscal year 2027 Alzheimer’s Research Program. The primary objective is to identify research focus areas and funding opportunities aimed at mitigating the impact of Alzheimer's and related dementias, specifically those associated with traumatic brain injury, military service, and diverse risks. The program seeks to improve the quality of life for Service Members, Veterans, and their families by funding solution-oriented research, including the development of digital and blood-based biomarkers for early diagnosis and the creation of precision prevention strategies. This action is strictly for information and planning purposes and does not constitute a formal solicitation, request for proposals, or request for quotations. No contracts will be awarded based on this announcement, and FY27 funds have not yet been appropriated. Interested parties from academia, industry, non-profit organizations, and federal agencies are invited to provide feedback via Survey Monkey by December 4, 2026. Respondents are cautioned not to submit proprietary or sensitive information through the survey portal as it cannot be protected. The effort is categorized under NAICS code 541714 and is managed by the Department of Defense in Fort Detrick, Maryland.

Defense Health Agency

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Traumatic Brain Injury and Psychological Health Research Program Public Request for Information

Solicitation # HT9427RFI2027TBIPHRP

The Defense Health Agency, under the Department of Defense and the Congressionally Directed Medical Research Programs, has issued a Request for Information under solicitation number HT9427RFI2027TBIPHRP. This action is strictly for strategic planning and is not a formal solicitation, request for proposals, or request for quotations. The primary objective is to gather feedback from academia, industry, non-profit organizations, and the public to inform the research focus areas and funding opportunities for the fiscal year 2027 Traumatic Brain Injury and Psychological Health Research Program. The program aims to optimize the prevention, assessment, and treatment of psychological health conditions and traumatic brain injuries to benefit Service Members, Veterans, and the general public. Interested parties are asked to provide input on research gaps and funding priorities, specifically regarding the prevention, screening, diagnosis, and treatment of these conditions. Responses must be submitted via Survey Monkey by December 11, 2026. Because the government cannot protect proprietary or sensitive information submitted through the survey platform, such data should not be included. This inquiry does not commit the program to incorporating the feedback into future funding opportunities, and no contract will be awarded based on this specific announcement. All inquiries regarding this RFI should be directed to Patrick M. Younkins.

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Barda - Aspr / Daappo / Barda Dcma

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Solicitation # USDA-NIFA-TOPIC-8.2

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National Institute of Food and Agriculture

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Quantitative Analysis of Longitudinal MR Images

Solicitation # 75N98027R00005

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National Institutes Of Health Olao

POSTED

7 days ago

DEADLINE

in 11 days

AI Contract Overview

The CDC Office of Acquisition Services is issuing a Notice of Intent to Sole Source for the West Virginia University Research Corporation under solicitation 98769. This project focuses on evaluating the health risks associated with respirable crystalline silica found in engineered stone countertops, specifically investigating the link between dust exposure during fabrication and the development of autoimmune diseases. The research aims to clarify the underlying mechanisms of these responses through animal studies involving oropharyngeal aspiration in mice. The study will utilize 48 mice across two strains, NZBWF1/J and C57BL/6J, to test the effects of two different engineered stone variants, Silestone and HybriQ, against a control group. Performance of the research will take place in Morgantown, West Virginia. The solicitation was posted on August 11, 2026, with a response deadline of August 21, 2026.

General Info

CDC sole source contract for WVU to study engineered stone silica health risks.

Agency

Department Of Health And Human Services → CDC Office Of Acquisition Services

NAICS

541714 - Research and Development in Biotechnology (except Nanobiotechnology)

Place of Performance

Morgantown, WV, 26506, USA

Set-Aside

NONE

Documents

Sole Source Justification for Research Services at WVU

justification-and-authorization

High

AI Contract Breakdown

Uniform Contract Format

Timeline

PhaseAwarded

PostedAug 11

Combined Synopsis

AwardedOct 30

Contract was awarded

Submission Closed

08/21/2026, 04:00:00 PM UTC

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Organization & Contact Information

AgencyDepartment Of Health And Human Services → CDC Office Of Acquisition Services

Contacts1 person available

OfficeATLANTA, GA, 30333, USA

Organization / AgencyDepartment Of Health And Human Services → CDC Office Of Acquisition Services

Office AddressATLANTA, GA, 30333, USA

Contacts

Kourtney Marshall

contact@example.gov

+1 (555) 000-0000

Full Description

Engineered stone countertops containing more than 90% crystalline silica have become increasingly popular among consumers in recent years. As a result, the rapidly growing workforce in this industry is at significant risk of a well-documented occupational hazard—overexposure to respirable crystalline silica (RCS), which can lead to progressive, irreversible, and potentially disabling pulmonary silicosis. Epidemiological studies have also linked occupational exposure to RCS with the occurrence of autoimmune diseases, including lupus erythematosus, systemic sclerosis, and rheumatoid arthritis. However, the relationship between the development of these autoimmune diseases and silica-induced inflammation and fibrosis remains unclear, and the underlying mechanisms of RCS-induced autoimmune responses have not been fully elucidated. This study hypothesizes that dust from engineered stone fabrication may cause serious health issues, especially triggering autoimmune responses. To test this hypothesis, animal studies are required. This project involves oropharyngeal aspiration studies to evaluate autoimmune responses to chronic exposure to emissions from engineered stone materials in mice. The project was initiated at CDC/NIOSH/HELD in 2024 and paused in 2025. The overall objective of this project is to evaluate the immune responses to dust released from engineered stone countertops during fabrication processes in mice to better understand worker health risks associated with these exposures. This study will employ a sensitization and challenge model to evaluate autoimmune responses following repeated exposure to engineered stone dust. To determine engineered stone dust (ESD)–induced autoimmune responses in mice, two strains of mice (NZBWF1/J and C57BL/6J) will be exposed to two ESD variants—Silestone (~90% crystalline silica) and HybriQ (~60% crystalline silica)—with evaluation at 90 days post-exposure. The study design will include two mouse strains, two ESD variants, and three exposure groups (Silestone, HybriQ, and PBS control), with 8 mice per group and a single exposure dose, followed by a 90-day post-exposure period. The total number of mice is 48 (24 NZBWF1/J and 24 C57BL/6J).