This Subcontract opportunity from Virginia was posted on June 9, 2025. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Preclinical Pharmacology and Toxicology Testing

Closed

State & Local

Submission Closed06/22/2025, 08:00:00 PM EDT

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541715

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SBIR / STTR

USDA SBIR/STTR Topic 8.6 — Rural and Community Development

Solicitation # USDA-NIFA-TOPIC-8.6

The USDA SBIR/STTR Topic 8.6 solicitation, managed by the National Institute of Food and Agriculture, seeks to improve the quality of life in rural America through the creation and commercialization of science-based technologies. The program focuses on addressing critical economic and social challenges, requiring applicants to explicitly define the rural problem they intend to solve and how their technology will provide a solution. While not limited to agriculture, projects must include objectives to evaluate their impact on the environment, climate mitigation, or the socio-economic development of rural communities. This opportunity is a total small business set-aside for entities with fewer than 500 employees. The USDA is looking for a diverse portfolio of projects that balance high-risk, high-reward innovations with the practical application of existing technologies. Interested parties can find further details through the National Program Leader, Carlos Ortiz, or via the official NIFA website.

National Institute of Food and Agriculture

POSTED

DEADLINE

USDA SBIR/STTR Topic 8.5 — Food Science and Nutrition

Solicitation # USDA-NIFA-TOPIC-8.5

The USDA SBIR/STTR Topic 8.5 solicitation, managed by the National Institute of Food and Agriculture, seeks to fund research and development projects focused on advancing food science and nutrition. The program prioritizes the creation of new processes, technologies, and products that enhance food safety, improve nutritional value, reduce food waste, and detect hazardous materials. Key objectives include developing climate-smart food systems, addressing food deserts, and creating products that combat diet-related chronic diseases. A successful project must result in a proof of concept for a patented process or a marketable product. This opportunity is a total small business set-aside for entities with fewer than 500 employees. The long-term strategic goals over the next decade include the commercialization of novel food systems to reduce foodborne illnesses, lower the carbon footprint of the food industry, and bridge socioeconomic gaps to ensure the accessibility of healthy, sustainably produced foods. Interested parties can coordinate with the National Program Leader, Dr. Junia Jean-Gilles Beaubrun, regarding this federal solicitation.

National Institute of Food and Agriculture

POSTED

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USDA SBIR/STTR Topic 8.8 — Biofuels and Biobased Products

Solicitation # USDA-NIFA-TOPIC-8.8

The USDA SBIR/STTR Topic 8.8 solicitation, managed by the National Institute of Food and Agriculture, seeks to advance the competitiveness of non-food biobased products and biofuels. The primary goal is to develop new or improved technologies that convert agricultural materials into value-added industrial products, thereby diversifying agriculture and strengthening its role as a raw material supplier for industry. Key research priorities include enhancing the cost-effectiveness of biobased products compared to non-agricultural alternatives and developing new products from industrial crops. This opportunity is a total small business set-aside under the SBIR/STTR mandate, limiting eligibility to companies with fewer than 500 employees. The solicitation was posted on August 11, 2026, and is overseen by Dr. David Songstad. Interested parties can find further details through the official NIFA website.

National Institute of Food and Agriculture

POSTED

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USDA SBIR/STTR Topic 8.13 — Plant Production and Protection - Engineering

Solicitation # USDA-NIFA-TOPIC-8.13

The USDA National Institute of Food and Agriculture is soliciting proposals under Topic 8.13 for the development and commercialization of engineering technologies designed to improve crop production and protection in both conventional and organic systems. The program focuses on creating scalable solutions that enhance system efficiency and profitability while protecting crops from pests and pathogens in an environmentally and economically sound manner. Applicants must provide detailed design specifications, functionality, reliability, and cost-benefit analyses, along with clear testing metrics and data collection methods. This solicitation is a total small business set-aside under the SBIR/STTR mandate for companies with fewer than 500 employees. Phase I applications must focus on early-stage, proof-of-concept research, and any adaptation of existing technologies to new crops or regions must demonstrate significant innovation. Projects that do not directly align with crop production and protection should be vetted by the National Program Leader to ensure they fit the program's objectives.

National Institute of Food and Agriculture

POSTED

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USDA SBIR/STTR Topic 8.4 — Management of Natural Resources

Solicitation # USDA-NIFA-TOPIC-8.4

The USDA SBIR/STTR Topic 8.4 solicitation, managed by the National Institute of Food and Agriculture, seeks to commercialize innovative technologies designed to monitor, protect, and improve the quality and quantity of natural resources. The program focuses on managing soil, water, air, and other natural resources within agricultural, forest, and rangeland landscapes to ensure climate-smart productivity and profitability. There is a specific emphasis on circular agriculture principles that utilize waste or byproducts to enhance soil health, reduce erosion, and optimize nutrient and water management. This opportunity is a total small business set-aside restricted to organizations with fewer than 500 employees. Interested parties can coordinate with the National Program Leader, Dr. Diomides Zamora, regarding the development of technologies that reduce waste streams while sustaining the delivery of natural and agricultural goods and services.

National Institute of Food and Agriculture

POSTED

DEADLINE

USDA SBIR/STTR Topic 8.3 — Animal Production and Protection

Solicitation # USDA-NIFA-TOPIC-8.3

The USDA SBIR/STTR solicitation for Animal Production and Protection, managed by the National Institute of Food and Agriculture, seeks innovative and marketable technologies to enhance the productivity, efficiency, and biosecurity of agricultural animals. The program prioritizes the development of tools for rapid disease detection, point-of-care treatment, and the creation of viable alternatives to antibiotics to combat pathogen resistance. Additionally, there is a strong emphasis on environmental stewardship, specifically regarding carbon sequestration and the optimization of manure management to reduce the ecological impact of animal agriculture. This opportunity is a total small business set-aside under the SBIR/STTR mandate, limiting eligibility to organizations with fewer than 500 employees. The primary goal is to ensure the safety of the national food supply and maintain the global competitiveness of American producers while contributing to worldwide food security. Interested parties can contact National Program Leader Dr. Amber Campbell for further information regarding this federal solicitation.

National Institute of Food and Agriculture

POSTED

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Glovebox Demonstration ProgramThe Glovebox Demonstration Program is a forecast opportunity issued by the National Nuclear Security Administration under the Department of Energy. This project falls under NAICS code 541715 and is designated as a small business set-aside. The performance of the contract is expected to take place in the District of Columbia. The current incumbent contractor for this program is the Merrick-SMSI Joint Venture LLP. Interested parties may coordinate with Chelsea Murphy, the Small Business Program Manager, regarding this acquisition.

National Nuclear Security Administration

POSTED

DEADLINE

AN12--NOVOCYTE 3000 PM&R Services Intent to Sole Source

Solicitation # 36C26227Q0114

The Department of Veterans Affairs intends to award a sole-source, firm-fixed-price contract to Agilent Technologies, Inc. for comprehensive service and maintenance of the Agilent NovoCyte 3000 benchtop flow cytometer, including the NovoSampler Pro automated sample loader, instrument workstation, and NovoExpress acquisition/analysis software. This requirement supports the Veteran Affairs San Diego Health Care Services campuses across San Diego and Imperial Counties, California. The scope of work includes 12-month top-priority repair coverage for all parts, labor, and travel, regular planned maintenance visits to minimize downtime, and full optimization and updates of software and data systems. Performance will be monitored by an assigned Principal Investigator, with services conducted Monday through Friday from 7:30 AM to 4:00 PM. The contract structure consists of a base year running from December 1, 2026, to November 30, 2027, with four subsequent option years extending through November 30, 2031. This procurement is being conducted under FAR 6.302-2 and FAR 13.5, utilizing NAICS code 541715. Invoicing must be submitted monthly in arrears via the Tungsten-Network System. While this is a notice of intent to sole source, the government will consider capability statements from other licensed providers with similar research service experience if submitted to Charity Cazee by 12:00 PM PT on November 13, 2026.

262-NETWORK Contract Office 22 (36C262)

POSTED

DEADLINE

ESMF Signal Processing and Forecasting Software EngineeringThe ESMF Signal Processing and Forecasting Software Engineering subcontract supports prime contractors on NSWC Carderock Navy projects. The scope of work involves developing wave signal processing source code, dynamic data quality algorithms, and ship motion forecast models specifically for Destroyers and Cruisers. Key deliverables include the production of new source code, comprehensive technical reports, and updated system diagrams. Personnel assigned to this effort must possess a Secret security clearance and maintain valid IAT/IAM certifications, such as Security+ CE or CISSP. This opportunity falls under NAICS code 541715 and is associated with the Department of Defense. Interested parties should note the response deadline of December 21, 2026.

POSTED

DEADLINE

AFSIM Integration and Modeling SpecialistThe AFSIM Integration and Modeling Specialist subcontract is a small business set-aside opportunity issued by the Department of Defense under the FA4861 99 Cons Lgc agency. The project focuses on providing specialized software integration and modeling support for Air Force mission planning projects. Key technical requirements include integrating MPST with the Advanced Framework for Simulation, Integration and Modeling, updating Suppressor modeling to align with aircraft capabilities, and delivering AFSIM training along with integrated models and updated code. Due to the sensitive nature of the work, personnel must possess Top Secret/SCI/SAP security clearances. The performance of the contract is located in zip code 89149, and the solicitation is categorized under NAICS code 541715. Interested parties must respond by November 20, 2026.

POSTED

DEADLINE

EmbraceHEALTH Clinical Research Network (EmbraceHEALTH CRN) - Coordinating Center

Solicitation # 75N94027R00003

The National Institute on Minority Health and Health Disparities (NIMHD) within the National Institutes of Health (NIH) has issued a Small Business Sources Sought notice for the EmbraceHEALTH Clinical Research Network (CRN) Coordinating Center. This market research effort seeks to identify qualified small businesses under NAICS code 541715, with a size standard of 1,000 employees or less, to potentially establish a small business set-aside. The anticipated contract will be an Indefinite Delivery, Indefinite Quantity (IDIQ) vehicle with an ordering period of approximately five years, where coordination activities for Research Consortia will be managed on a task order basis. The selected contractor will be responsible for establishing and maintaining the Coordinating Center infrastructure, providing foundational support across the research lifecycle, including study readiness, implementation, monitoring, and close-out. Key requirements include the development of a Network Operations Plan, the facilitation of single Institutional Review Board (sIRB) arrangements, and the management of deidentified research data for transfer to NIH SCHARE. All data management must be FISMA-compliant, and website development must meet Section 508 standards. Additionally, the contractor must implement rigorous quality assurance processes, including the establishment of a Data and Safety Monitoring Board (DSMB) and standardized procedures for reporting protocol deviations and corrective actions. Interested small businesses must submit a detailed capability statement by November 23, 2026, at 4:00pm EST. Submissions must include the company name, Unique Entity ID, physical address, and point of contact information, along with evidence of experience managing multi-site clinical research networks. Capability statements should be submitted in MS Word or PDF format to Jordan Neal and Gannon White, referencing notice number 75N94027R00003.

National Institutes Of Health Nichd

POSTED

DEADLINE

Request for Proposal (RFP) - Resilient Missile Warning Tracking (RMWT) Low Earth Orbit (LEO) Ground Entry Points (GEPs)

Solicitation # FA240126R0003

The Space Development Agency (SDA) is soliciting proposals under solicitation FA240126R0003 for the Resilient Missile Warning Tracking (RMWT) Low Earth Orbit (LEO) Ground Entry Points (GEPs) effort. This acquisition is structured as an Indefinite Delivery/Indefinite Quantity (IDIQ) contract with a ceiling of 369 million dollars. The scope of work encompasses the development, procurement, installation, integration, testing, and maintenance of Tranche 3 Ground Entry Points at multiple globally dispersed locations. Key requirements include civil engineering for site construction, the deployment of communications shelters, antennas, optical terminals, and networking equipment, as well as the creation of Ground Support Equipment and Auxiliary Development Units. The contract features an ordering period from March 31, 2027, to September 30, 2031, with an option period extending through September 30, 2035. Award will be based on a best-value tradeoff process where technical, management, and past performance factors are significantly more important than price. Proposals are due by 4:00 PM Eastern Time on November 23, 2026, and must be submitted in seven volumes via the DoD Secure Access File Exchange. Large business offerors must commit to a minimum quantitative requirement of 5 percent small business participation. The contract utilizes a mix of Firm Fixed Price for primary labor and materials, and Cost No Fee for other direct costs and travel.

FA2401 Space Development Agency Sda

POSTED

3 days ago

DEADLINE

in 15 days

AI Contract Overview

Virginia Commonwealth University is seeking a subcontractor for Preclinical Pharmacology and Toxicology Testing. The scope of work involves conducting both in vitro and in vivo studies to evaluate the efficacy, safety, and toxicity of drugs for various pharmaceutical and biotech clients. The opportunity was posted on June 9, 2025, with a response deadline of June 23, 2025. This subcontract falls under NAICS code 541715, focusing on research and experimental development in the biotechnology sector.

General Info

Agency

Virginia Commonwealth University

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

VA, USA

Set-Aside

NONE

Documents

This scope was carved out of 194610118AZ.

The full solicitation package (4 documents), including the RFP, is on the prime solicitation, not on this scope.

View the prime solicitation

RFP Number:-194610118AZ-Pre-Qualified Contract Research Organizations (CROs)

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Timeline

PhaseClosed

PostedJun 9

subcontract

Response DeadlineJun 22

Deadline has passed

Submission Closed

06/22/2025, 08:00:00 PM EDT

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Organization & Contact Information

AgencyVirginia Commonwealth University

ContactsNo contacts available

OfficeN/A

Organization / AgencyVirginia Commonwealth University

Office AddressN/A

ContactsNo contact information available

Full Description

Conduct in vitro and in vivo studies to evaluate drug efficacy, safety, and toxicity for pharmaceutical and biotech clients.

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Preclinical Pharmacology and Toxicology Testing

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