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Protein Engineering & Biochemistry Specialist

Active

Federal

Response Deadline10/19/2026, 12:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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This subcontract for the Defense Advanced Research Projects Agency involves providing specialized protein engineering and biochemistry services to support prime contractors on biological research projects. The scope of work focuses on developing and validating editing mechanisms for various structural protein families, including globular, transmembrane, and fibrous types, by leveraging in silico predictions and structural modeling. The technical execution requires the use of advanced experimental validation tools such as Mass Spectrometry, NMR, or Cryo-EM. The primary deliverables for this engagement are validated biochemistry protocols and comprehensive generalizability data. Interested parties must respond by October 19, 2026, under NAICS code 541715.

General Info

DARPA subcontract for protein engineering services; deliverables due by October 19, 2026.

Agency

Department Of Defense → Defense Advanced Research Projects AgcyView Agency

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)View NAICS

Place of Performance

VA

Set-Aside

NONE

Documents

This scope was carved out of DARPA-PS-26-129.

The full solicitation package (10 documents), including the RFP, is on the prime solicitation, not on this scope.

View the prime solicitation

Protein ENGineering (PENG)

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Timeline

PostedAug 7

subcontract

Response DeadlineOct 19

Submission deadline

Response Deadline

10/19/2026, 12:00:00 PM UTCin about 1 month

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Organization & Contact Information

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AgencyDepartment Of Defense → Defense Advanced Research Projects Agcy

ContactsNo contacts available

OfficeN/A

Organization / Agency

Department Of Defense → Defense Advanced Research Projects Agcy

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Office AddressN/A

ContactsNo contact information available

Full Description

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Performs foundational biochemistry for prime contractors on DARPA biological research projects. Develops and validates editing mechanisms for globular, transmembrane, and fibrous structural protein families using in silico predictions and structural modeling. Utilizes Mass Spec, NMR, or Cryo-EM for experimental validation. Delivers validated biochemistry protocols and generalizability data.

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