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This Government Contract opportunity from Department Of Health And Human Services was posted on June 11, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

REGARDS DNA Extraction and Quantification

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NIH-NOI-PCA-NIA-01601Federal

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The Department of Health and Human Services, through the National Institutes of Health and the National Institute on Aging’s Center for Alzheimer’s and Related Dementias, intends to sole-source a firm-fixed-price contract to the University of Vermont Laboratory for Clinical Biochemistry Research for specialized laboratory services supporting the REGARDS project. The contract will require the extraction, quantification, handling, and shipment of DNA samples from approximately 12,000 biospecimens stored in the REGARDS repository to support a genome-wide association study. The work will be performed at the contractor’s facility in Colchester, Vermont, using the Qiagen Puregene DNA Purification Kit for manual extraction and PicoGreen for quantification, with each sample requiring a minimum of 1 microgram of DNA at a concentration of 50 nanograms per microliter or higher. The contractor will manage repository access, create cryovials for storage, maintain a detailed inventory, ship samples to CARD facilities, report quantification results, and identify failed extractions. Quarterly progress reports including sample counts, timelines, and issue resolution status are required, along with the provision of a dedicated project manager as the primary point of contact. The period of performance is scheduled from July 1, 2026, through June 30, 2029. Sole sourcing is justified under FAR 6.302-1 because the University of Vermont is the sole entity with custody of and access to the proprietary, non-replaceable REGARDS biospecimens and repository infrastructure, which no other source can replicate. Although this is not a solicitation, interested parties may submit capability statements by June 23, 2026, demonstrating their ability to access the REGARDS biospecimens and meet all technical requirements, though no reimbursement will be provided for such submissions. The NAICS code is 541380 and the PSC is 6550, and compliance with Section 508 of the Rehabilitation Act is required.

General Info

Sole source contract to University of Vermont for DNA services on 12,000 REGARDS biospecimens.

NAICS

541380 - Testing Laboratories and Services

Place of Performance

Colchester, VT, 05446, USA

Set-Aside

NONE

Documents

2

SOW for DNA Extraction Services for REGARDS Project

PDF, High priority: read this firstsow
High

NIH Notice of Intent to Sole Source - REGARDS DNA Extraction and Quantification

PDF, Low priorityspecial-notice
Low

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Timeline

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Posted

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Submission Closed

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health Olao
Contacts2 people available
OfficeBETHESDA, MD, 20892, USA
Office AddressBETHESDA, MD, 20892, USA
Contacts

Full Description

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Title: Notice of Intent to Sole Source – REGARDS DNA Extraction and Quantification


Notice ID: NIH-NOI-PCA-NIA-01601


Department/Ind. Agency: HEALTH AND HUMAN SERVICES, DEPARTMENT OF
Sub-tier: NATIONAL INSTITUTES OF HEALTH
Office: NATIONAL INSTITUTE ON AGING


Active Contract Opportunity


Notice Type: Special Notice


Original Published Date: June 11, 2026
Original Response Date: June 23, 2026, 11:00 AM Eastern Time
Initiative: None



Classification


Original Set Aside: N/A
Product Service Code: 6550 – In Vitro Diagnostic Substances, Reagents, Test Kits and Sets
NAICS Code: 541380 – Testing Laboratories and Services


Place of Performance


Primary Place of Performance:
University of Vermont Laboratory for Clinical Biochemistry Research
Colchester Research Facility
360 South Park Drive, Room 224
Colchester, VT 05446
United States


Description


This is a Notice of Intent to Sole Source and is not a request for competitive proposals, quotations, or bids.


The Department of Health and Human Services (HHS), National Institutes of Health (NIH), National Institute on Aging (NIA), Center for Alzheimer’s and Related Dementias (CARD), intends to negotiate and award a sole source firm-fixed-price contract to:


University of Vermont Laboratory for Clinical Biochemistry Research
Colchester Research Facility
360 South Park Drive, Room 224
Colchester, VT 05446


The purpose of this requirement is to obtain specialized laboratory support services for the Reasons for Geographic and Racial Difference in Stroke (REGARDS) project. The contractor shall perform DNA extraction, DNA quantification, repository handling, preparation, and shipment of extracted DNA samples for approximately 12,000 REGARDS participant biospecimens in support of a genome-wide association study (GWAS).


The contractor shall:


  • Evaluate frozen packed cell sample availability in the REGARDS repository;
  • Select and pull samples from the repository in batches;
  • Perform manual DNA extraction using the Qiagen Puregene DNA Purification Kit;
  • Perform DNA quantification using PicoGreen;
  • Create cryovials of DNA for the REGARDS repository;
  • Create and maintain tracking inventory for extracted DNA samples;
  • Prepare 1 ug or more DNA per sample at a concentration of 50 ng/uL or greater;
  • Ship extracted DNA samples to CARD facilities;
  • Provide DNA quantification results to the Government; and
  • Identify any samples for which extraction failed.

The anticipated period of performance is July 1, 2026 through June 30, 2029.


The statutory authority for this sole source acquisition is 41 U.S.C. 3304(a)(1), as implemented by FAR 6.302-1, Only One Responsible Source and No Other Supplies or Services Will Satisfy Agency Requirements.


The University of Vermont Laboratory for Clinical Biochemistry Research is the only known source capable of meeting the Government’s requirement because it designed and led the biosample collection effort for the REGARDS study, maintains the REGARDS biosample repository, serves as the REGARDS central analysis laboratory, and has custody of and access to the proprietary, unique, and non-replaceable REGARDS participant biospecimens required for this effort. Although other commercial laboratories may provide general DNA extraction and quantification services, no other source is known to possess the proprietary REGARDS starting samples or repository access required to perform this requirement.


This notice is not a solicitation. However, any responsible source that believes it is capable of meeting the Government’s requirement may submit a capability statement demonstrating its ability to satisfy the requirement described herein. Responses must clearly demonstrate the offeror’s capability to provide access to the proprietary REGARDS biospecimens and repository services, as well as the required DNA extraction, quantification, handling, and shipment services.


All capability statements received by the response date and time will be considered by the Government. A determination by the Government not to compete this proposed action based on responses to this notice is solely within the discretion of the Government.


No solicitation document is available. The Government will not reimburse respondents for any costs associated with submission of capability statements.


Attachments/Links


None at this time.


Contact Information


Primary Point of Contact


Linda Smith
Contracting Officer
contact@example.gov


Secondary Point of Contact


Danielle Tines
Procurement Technician
contact@example.gov


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