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This Sources Sought opportunity from Department Of Health And Human Services was posted on May 21, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

RFI - Medical Countermeasures for the Treatment of Drug-Resistant Fungal Infections

Closed
RFI-MCM-TDRFI-BARDA-2026Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541715
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Solicitation # DARPA-SN-27-13
The Defense Advanced Research Projects Agency (DARPA) Information Processing Techniques Office (IPTO) has issued a Request for Information (RFI) under solicitation number DARPA-SN-27-13 titled Verification and Compliance Checking for Natural-Language Network Requirements (FastVacc). The agency is seeking information on tools, practices, and approaches to reduce the time and cost of verifiable compliance checking for network security requirements by two to three orders of magnitude. The objective is to develop a capability that can process natural-language requirements documents, such as Zero Trust Architecture or Commercial Solutions for Classified packages, and concrete network configurations to identify inconsistencies, redundancies, and incompleteness in an offline phase, while providing near real-time verification of configurations with human-understandable output. This RFI is not a formal solicitation for proposals and does not constitute a binding contract. Interested respondents must submit their information by November 13, 2026, via email to [email hidden]. Submissions should consist of a one-page narrative and up to two slides featuring visual depictions of key concepts, including a completed version of Table 1. All responses must be submitted at the unclassified level in unprotected Microsoft Word, PowerPoint, or PDF formats, adhering to specific formatting guidelines including 12-point font and one-inch margins. Any proprietary information must be clearly labeled as Proprietary, and the use of the term Confidential is strictly prohibited for proprietary business data.
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Bolstering Underutilized Industry by Leveraging Technology Transfer (BUILTT) pilot program
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The Department of Energy, in partnership with the National Nuclear Security Administration, has announced the Bolstering Underutilized Industry by Leveraging Technology Transfer (BUILTT) pilot program. This initiative, conducted by the Nevada National Security Sites, Y-12 National Security Complex, and Kansas City National Security Campus, aims to assist qualified U.S. small and medium-sized businesses in manufacturing low-volume, high-impact technologies developed by DOE/NNSA Labs, Plants, and Sites. These technologies, which include specialized optical imaging, radiation and chemical sensing systems, precision electrical components, and advanced materials, often have limited commercial markets but are critical for government mission requirements. Under the program, selected businesses may receive a Cost Reduction License (CRL) for a nominal fee, granting them the rights to produce specified technologies for sale to the DOE, NNSA, and other government customers at pre-negotiated prices. Eligibility is limited to U.S.-based SMBs, with preference given to those near participating sites or those with SBA 8(a) or HUBZone designations. Interested parties are evaluated based on their technical and manufacturing capabilities, financial capacity, and ability to meet regulatory and security requirements. Responses must be submitted to the Technology Partnerships and Intellectual Property Office by April 1, 2027, and are categorized under NAICS code 541715.
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Solicitation # RFI-PGI-20260929
The Department of the Navy is conducting a Request for Information under solicitation RFI-PGI-20260929 to gather industry feedback for the Pacific Greenfield initiative. This effort aims to establish an advanced manufacturing and industrial resilience campus on non-excess Navy property on Oahu, Hawaii, to reduce reliance on long-lead continental United States supply chains. The initiative focuses on creating theater-scale production capabilities for metals, composites, electronics, and large-format printing, bridging the gap between prototyping and industrial production of hundreds to thousands of units. Key priorities include the development of environmentally resilient, industrial-scale facilities integrated with modern utility infrastructure, grid-interactive storage, and circular resource-recovery solutions, while simultaneously strengthening the local Hawaii workforce through training pipelines and apprenticeships. The Navy is seeking input on site requirements, infrastructure needs, development timelines, and diverse acquisition and financing models, such as Enhanced Use Leases, Other Transaction Authorities, and joint ventures. A central technical goal is the implementation of a Born Qualified approach to digital engineering, utilizing in-situ process monitoring and digital workflows to ensure components meet naval and airworthiness standards at the point of production. This RFI is strictly for market research and planning purposes; it does not constitute a solicitation, does not commit the government to a contract, and will not result in payment for submitted information. Responses are due by 17:00 HST on November 10, 2026, and are limited to 20 pages.
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Solicitation # W912CH-26-S-0001
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NAICS: 541715
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ARTIFICIAL INTELLIGENCE AND NEXT GENERATION DISTRIBUTED COMMAND AND CONTROL
Solicitation # FA875023S7006
The Department of the Air Force, Air Force Materiel Command, AFRL Rome Research Site, is soliciting research and development efforts under Broad Agency Announcement FA8750-23-S-7006 to advance Artificial Intelligence and Next Generation Distributed Command and Control. The program aims to transform Joint Force C2 capabilities across strategic, operational, and tactical levels, specifically focusing on the battle management of AI to enable operators to monitor, adapt, and deploy AI models in austere environments to counter AI drift. This open, two-step BAA is effective until August 30, 2028, and accepts initial submissions in the form of three-page white papers, with formal proposals accepted by invitation only. Total estimated funding for the BAA is approximately $99 million, with individual awards typically ranging from $200,000 to $20 million and performance periods generally not exceeding 48 months. Awards may be issued as FAR-based procurement contracts, DODGARS-based grants and cooperative agreements, or Other Transactions. Evaluation is based on a trade-off process considering overall scientific and technical merit, related experience, solution maturity and openness, and cost realism. Additionally, assistance instruments must adhere to Gold Standard Science principles per Executive Order 14303. Offerors must comply with strict security and organizational conflict of interest requirements, including the disclosure of foreign influence and the submission of a DD Form 2345.
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AI Contract Overview

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The Center for Biomedical Advanced Research and Development Authority (BARDA) within the Administration for Strategic Preparedness and Response (ASPR) at the U.S. Department of Health and Human Services is issuing a Request for Information (RFI-MCM-TDRFI-BARDA-2026) to gather market intelligence on current and emerging capabilities for treating drug-resistant fungal infections. This effort aims to inform future acquisition strategies for medical countermeasures that address secondary fungal infections resulting from pandemic influenza, emerging infectious diseases, or chemical, biological, radiological, nuclear, or high-yield explosive (CBRNE) threats. Respondents are expected to provide detailed information on their drug substance and drug product manufacturing processes, including scalability, domestic production capacity, and a plan to onshore both drug substance synthesis and fill-finish operations if currently lacking in the United States. The RFI seeks evidence of a five-year shelf-life for both the drug substance and final drug product, along with comprehensive clinical, nonclinical, and regulatory documentation including Phase 1 through Phase 3 trial designs, FDA correspondence, and a proposed timeline for New Drug Application or supplemental NDA submission. Product delivery options must include either direct delivery to the Strategic National Stockpile or management of vendor-managed inventory by the sponsor. The response must be submitted electronically by June 21, 2026, limited to 12 single-sided pages, and must indicate whether the respondent is registered as a small business. All proprietary information must be clearly marked with restrictive legends; unmarked submissions will be deemed to carry unlimited rights for government use. The solicitation number is MCM TDRFI: BARDA-2026, with NAICS code 541715, and no set aside is in effect. This notice is strictly for planning purposes and does not obligate the government to award a contract, nor does it include pricing, evaluation factors, or formal contract clauses. Point of contact for all inquiries is Audrey Glover and Jonathan Gonzalez, Contracting Officer, at HHS.

General Info

BARDA seeks input from businesses on drug-resistant fungal infection treatments by June 21, 2026.

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

DC, USA

Set-Aside

NONE

Documents

1

RFI BARDA-2026 Medical Countermeasures for Drug-Resistant Fungal Infections

DOCX, High priority: read this firstrfi
High

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Timeline

PhaseClosed
Posted

Sources Sought

Response Deadline

Deadline has passed

Submission Closed

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → Barda - Aspr / Daappo / Barda Dcma
Contacts2 people available
OfficeWASHINGTON, DC, 20515, USA
Office AddressWASHINGTON, DC, 20515, USA
Contacts
Audrey Glover
Jonathan Gonzalez Contracting Officer

Full Description

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The Center for the Biomedical Advanced Research and Development Authority (BARDA), Administration for Strategic Preparedness and Response (ASPR) at the U.S. Department of Health and Human Services (HHS), is issuing this Request for Information (RFI) to collect feedback from current and prospective antifungal development partners. Information obtained from this RFI will serve as continued planning for potential future acquisitions and programs. The information collected in response to this RFI is intended to strengthen BARDA’s understanding of the current and future marketplace. This notice seeks information from Other than Small Businesses (OTSB) and Small Businesses (SB) regarding their qualifications, experience, and capabilities.

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NAICS: 541714
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Request for Proposals (RFP) - BARDA Vaccine Medical Countermeasures for Pandemic Influenza Preparedness & Response
Solicitation # 75A50126R00001_RFP_NPIVS_27
The Biomedical Advanced Research and Development Authority (BARDA) is soliciting proposals for the Vaccine Medical Countermeasures for Pandemic Influenza Preparedness and Response Program. The objective is to maintain a permanent readiness posture against high-threat influenza and other viruses with pandemic potential. Selected contractors will provide essential services, personnel, and facilities to produce vaccines, antigens, and adjuvants, while generating the necessary analytical, nonclinical, clinical, and chemistry, manufacturing, and controls data for FDA submission to support rapid regulatory decisions. To be eligible, offerors must be capable of producing vaccines against influenza strains with pandemic potential and demonstrate success through a U.S. influenza vaccine license or a submitted Biologics License Application. The government intends to award contracts to four offerors based on the Highest Technically Rated Offerors with a Fair and Reasonable Price methodology. Evaluation focuses on capabilities, past performance, and price, with a minimum requirement of a High Confidence rating for technical capabilities. The contract structure consists of a 60-month base period and a 60-month option period, with a minimum guarantee of 50,000 dollars. Key requirements include the development of comprehensive manufacturing and business continuity plans, adherence to strict ASPR security and cybersecurity standards, and the use of the Department of Treasury Invoice Processing Platform for quarterly invoicing. Performance is monitored through a BARDA dose tracker, and final acceptance is triggered by the submission of a final report and updated dose tracking data.
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Automated Ultrasound-Based, Super Intelligence (SI)-Enabled Fracture Detection
Solicitation # BARDA-FY27-10192026
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