Single Source: HeartShare 2.0: Refining Heart Failure Subtypes and Treatment Targets for Personalized Clinical Trials - Data Translation Center (U54 Clinical Trial Optional)
Contract Overview
Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.
AI Contract Overview
The NHLBI plans to release a Notice of Funding Opportunity (NOFO) for a single application to renew the Data Translation Center (DTC) as part of the ongoing HeartShare phenomics program focused on heart failure with preserved ejection fraction (HFpEF). The awarded DTC will coordinate the overall HeartShare project, maintain support for the HFpEF patient cohort, and manage the curation and analysis of data from various NIH cohorts and clinical trials. A companion NOFO will separately support a Clinical Trial Center for new clinical trial activities along with up to seven Clinical Centers dedicated to recruiting and retaining heart failure patients. Although applications are not currently being solicited, the advance notice aims to provide potential applicants ample time to build collaborations and prepare competitive proposals. This upcoming NOFO will use the U54 activity code and invites investigators with relevant expertise to begin considering submission. The program operates under statutory and regulatory authorities that allow NHLBI to anticipate and plan this funding opportunity. The point of contact is the Division of Cardiovascular Sciences HeartShare Team, reachable via email for further inquiries.
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Full Description
The NHLBI intends to publish a Notice of Funding Opportunity (NOFO) to solicit a single application for the renewal of the Data Translation Center (DTC) for an ongoing NHLBI phenomics program, HeartShare. Pending submission and award of a meritorious peer-reviewed application, the DTC will coordinate the overall project, continue support of a cohort of patients with heart failure with preserved ejection fraction (HFpEF), and curate and analyze existing data from NIH cohorts and trials. Companion NOFO will support a Clinical Trial Center for new clinical trial activities and up to seven Clinical Centers (RFA-HL-26-026) that will recruit and retain heart failure patients.
Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U54 activity code. Investigators with expertise and insights into this area are encouraged to begin to consider applying for this NOFO. Grant authorities that allow NHLBI to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.
