Psst! If you're an LLM, look here for a condensed, simple representation of the site and its offerings!

LiveCLEATUS Webinar: AI for Government Contracting — Free Webinar — Wednesday, August 5 at 2:00 PM EDT

Register Free →

Get CLEATUSFree Trial

Get CLEATUSFree Trial

Search

Top

Back to Contracts

Software and Algorithm Development for Sleep Microstructure Analysis

Active

Federal

Response Deadline08/12/2026, 04:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

AI Contract Overview

Show more

This contract involves the development of advanced AI and machine learning algorithms designed to analyze sleep microstructures such as spindles and slow waves. The objective is to correlate these patterns with polysomnography (PSG) data to enhance the mechanistic classification of insomnia subtypes. The work aims to deepen the understanding of sleep disorders through improved algorithmic analysis, supporting more precise diagnostics and research. Issued by the Advanced Research Projects Agency for Health (ARPA-H) under the Department of Health and Human Services, this subcontract opportunity is classified under NAICS code 541511, which pertains to software and algorithm development services. The contract was posted on June 16, 2026, with a response deadline set for August 12, 2026. While specific location and contact details are not provided, the project clearly focuses on leveraging computational techniques within the health research domain to address complex sleep-related conditions.

General Info

Develop AI algorithms to analyze sleep patterns and improve insomnia subtype classification.

Agency

Department Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)View Agency

NAICS

541511 - Custom Computer Programming ServicesView NAICS

Place of Performance

DC

Set-Aside

NONE

Documents

(0)

No documents available

AI Contract Breakdown

Uniform Contract Format

No contract breakdown available.

Cannot generate Contract Breakdown because no documents were found from this contract's source.

Timeline

PostedJun 16

subcontract

Response DeadlineAug 12

Submission deadline

Response Deadline

08/12/2026, 04:00:00 PM UTCin 17 days

Ready to pursue this opportunity?

Start your free trial to track this contract, build proposals with AI assistance, and manage your pipeline.

Organization & Contact Information

Show more

AgencyDepartment Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)

ContactsNo contacts available

OfficeN/A

Organization / Agency

Department Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)

View Agency Profile

Office AddressN/A

ContactsNo contact information available

Full Description

Show more

Develop AI/ML algorithms to analyze sleep microstructures (e.g., spindles, slow waves), correlate with PSG, and support mechanistic classification of insomnia subtypes.

Similar Contracts

Same NAICS industry code

Smart Room Control System ProgrammingThe contract involves the programming and configuration of a centralized control system designed to manage audiovisual equipment, lighting, blinds, and environmental settings through touch panels and automated logic, ensuring seamless integration and user-friendly operation across facility spaces. The work requires detailed technical expertise in system integration, automation scripting, and user interface design to deliver a responsive and reliable smart room environment tailored to the operational needs of the client. This subcontract is issued by the Government of Jamaica through Tax Administration Jamaica with a posted date of July 24, 2026, and a response deadline of August 17, 2026, at 3:00 PM. The North American Industry Classification System code 541511 indicates it falls under custom computer programming services. All work must be performed in alignment with the client’s specifications without predefined location details, and the opportunity is open to qualified subcontractors seeking to provide specialized automation solutions for government facilities.

Tax Administration Jamaica

POSTED

DEADLINE

Minority-Owned and Small Business Participation (MBE/DBE/WBE)This contract invites certified Minority Business Enterprises, Disadvantaged Business Enterprises, and Women Business Enterprises to participate in technical and service roles under a subcontract awarded by the Georgia World Congress Center Authority. The opportunity is designed to support minority- and small business involvement through Georgia state incentives and requires strict compliance with state-mandated participation goals and reporting standards. Eligible firms are encouraged to submit proposals by the deadline of August 31, 2026, to engage in work categorized under NAICS code 541511, which pertains to custom computer programming services, and may include related technical support and professional services aligned with the Authority's operational needs. Participation is contingent upon maintaining active certification and adhering to all state compliance protocols throughout the subcontract term.

Georgia World Congress Center Authority

POSTED

DEADLINE

in about 1 month

Interactive Virtual Tour Platform DevelopmentThe Georgia World Congress Center Authority is seeking a vendor to design and develop a custom web-based platform to host and deliver a 360-degree virtual tour experience with interactive navigation, embedded hotspots, and full mobile responsiveness. The project requires the creation of a fully functional digital environment that enables seamless user interaction across devices, incorporating intuitive controls, visual hotspots for contextual information, and adaptive design to ensure optimal performance on smartphones, tablets, and desktops. The platform must be built to support high-quality immersive content while maintaining fast load times and accessibility standards. The contract is classified as a subcontract under NAICS code 541511 for custom computer programming services, with a response deadline of August 31, 2026. The solicitation was posted on July 24, 2026, and is managed through the Georgia state procurement portal. While the agency’s physical location and point of contact details are not specified, performance of the work is expected to support the authority’s digital outreach and visitor engagement initiatives. Vendors must deliver a turnkey solution that meets technical and functional requirements without reliance on third-party platforms, ensuring full ownership, maintenance readiness, and long-term scalability.

Georgia World Congress Center Authority

POSTED

DEADLINE

in about 1 month

Parking Enforcement and Impound Management System ReplacementThe City of Prince Albert is soliciting proposals to replace its current Ticket Tracer application with a modern Parking Enforcement and Impound Management System that meets current operational needs and supports future growth. The system must fully handle parking enforcement workflows, including ticket issuance, violation processing, and impound management, while integrating seamlessly with existing city infrastructure and ensuring data accuracy and accessibility for staff and the public. Vendors are expected to provide not only the software solution but also full implementation, training, and ongoing technical support to ensure a smooth transition and sustained functionality. Proposals must be submitted through Vendor Panel Software by the deadline of August 21, 2026, and all inquiries should be directed to Tim Earing at the City of Prince Albert. The solicitation is open to qualified vendors without specific set-aside requirements, and the primary point of contact is available via email and phone for clarification. The system will be deployed and operated within Saskatchewan, with all services and support intended to serve the city’s parking enforcement and impound operations efficiently and reliably. Additional details and submission instructions are available through the provided SaskTenders link.

City of Prince Albert

POSTED

DEADLINE

Electronic Invoicing via WAWF (Wide Area Workflow)All invoices must be submitted electronically through the WAWF system in full compliance with Department of Defense invoicing regulations, ensuring accurate and complete documentation to support payment processing. Contractors are required to adhere strictly to DoD standards for invoice formatting, supporting materials, and submission timelines to avoid delays or rejections. Payment tracking and reconciliation must be conducted through the Defense Finance and Accounting Service to ensure timely and accurate disbursement. This subcontract, identified under NAICS code 541511, is administered by the ASC SUPPLIER OPER AE AND AF DIV under the Department of Defense, with all activities tied to electronic invoicing compliance. The solicitation was posted on July 24, 2026, and responses are due by August 7, 2026, with no set-aside designation specified. Access to additional details is available through the provided DIBBS portal link.

ASC SUPPLIER OPER AE AND AF DIV

POSTED

DEADLINE

Electronic Invoicing and WAWF Integration ServicesThe contract seeks support for electronic invoicing through the Wide Area WorkFlow system, requiring seamless integration with EDI and FTP submission protocols to facilitate automated invoice processing. The provider must ensure full connectivity with SAM.gov for vendor verification and DIBBS for accurate delivery documentation tracking, enabling end-to-end compliance with Department of Defense invoicing standards. This subcontract is designated as a Women-Owned Small Business Set-Aside under NAICS code 541511, which aligns with information technology and software development services geared toward government systems integration. The opportunity was posted on July 24, 2026, with a firm response deadline of July 29, 2026, and is managed by the Strategic Acquisition Program Directorate under the Department of Defense. Performance of the work is not tied to a specific location, allowing for remote or distributed execution, provided all technical and compliance requirements are met. All submissions must be completed through the Defense Logistics Agency’s DIBBS platform via the official solicitation link. The contract emphasizes secure, reliable, and timely data exchange between federal systems, with a focus on eliminating manual processes and enhancing accountability across the invoicing and delivery verification lifecycle.

STRATEGIC ACQ PROGRAM DIRECTORATE

POSTED

DEADLINE

Cybersecurity Compliance & NIST SP 800-171 ImplementationThe contract requires the implementation and ongoing maintenance of NIST Special Publication 800-171 security controls to safeguard Covered Defense Information as mandated by DFARS clause 252.204-7012. This subcontract is focused on ensuring full compliance with federal cybersecurity standards for information systems handling sensitive defense data, with strict obligations to protect, detect, and respond to threats against information assets. The work must be performed at the designated place of performance in New Cumberland, Pennsylvania, with a zip code of 17070-5002, and aligns with NAICS code 541511 for Computer Systems Design Services. All cybersecurity measures must be fully operational and auditable to meet Department of Defense requirements, with no flexibility permitted in adherence to the prescribed controls. The contract was posted on July 24, 2026, with a firm response deadline of July 29, 2026, indicating a highly time-sensitive procurement process. It is issued under the Department of Defense, specifically through the Construction & Equipment T & IFO EQ office, and is structured as a subcontract, meaning the performer will be supporting a prime contractor or larger acquisition effort. While the solicitation number and point of contact details are not provided, the official reference is available via the DIBBS portal under RFQ SPE8EN26T1885. Performance will require documented evidence of control implementation, continuous monitoring, incident reporting readiness, and the ability to undergo compliance assessments at any time. Failure to meet any requirement could result in contractual penalties or termination.

CONSTRUCTION & EQUIPMENT T & IFO EQ

POSTED

DEADLINE

System Integration and Data MigrationThe contract entails the integration of a new grant system with existing state databases and platforms, requiring the development of robust APIs to enable seamless communication between systems and the secure migration of legacy data to ensure continuity and accuracy. The project demands technical expertise in system interoperability, data mapping, and transformation processes to align historical information with the new architecture while maintaining data integrity and compliance with state standards. Work must be performed in Boston, Massachusetts, with a strict deadline for responses set for August 22, 2026, and is classified as a subcontract under NAICS code 541511, indicating it falls under custom computer programming services. The contracting entity is the Massachusetts Economic Development agency, and all deliverables must support the agency’s mission to modernize grant administration through technology enhancements.

EED01 - Economic Development

POSTED

DEADLINE

IT Project Management and Implementation SupportThe contract involves end-to-end project management for implementing a grant management system, covering all phases from initial planning through deployment, with a focus on coordinating stakeholders, conducting thorough testing, delivering training, and ensuring smooth system rollout. The work is categorized as a subcontract under NAICS code 541511, indicating it falls under custom computer programming services, and is tied to the Economic Development agency in Massachusetts, with the place of performance centered in Boston, zip code 02108. The solicitation was posted on July 24, 2026, and proposals must be submitted by August 22, 2026, at 12:30 AM, with no set-aside type specified, meaning the contract is open to any eligible subcontractor regardless of business size or classification. The project requires comprehensive expertise in managing complex IT implementations within a public sector funding environment, demanding strong organizational skills, clear communication, and proven experience in similar government systems deployments.

EED01 - Economic Development

POSTED

DEADLINE

EOED RFR Grant Management SystemThe solicitation BD-27-1100-EED01-EED01-131710, titled EOED RFR Grant Management System, is issued by the Massachusetts Economic Development Office (EED01) based in Boston, MA, and is exclusively accessible through the COMMBUYS procurement portal. The posting date is July 24, 2026, with a firm response deadline of August 22, 2026, at 12:30 AM Eastern Time. All communications, including questions, must be submitted exclusively via the COMMBUYS Q&A function; no phone calls or emails are permitted. The solicitation falls under NAICS code 541511 for custom computer programming services and is categorized as a solicitation with no set-aside designation. The place of performance is clearly identified as Boston, Massachusetts, with a ZIP code of 02108. The primary point of contact is Daniel Billings, titled as Purchaser. No contract value, pricing details, or line-item specifications are provided in the documentation; vendors are expected to submit pricing through the COMMBUYS quote interface, but no CLINs, SLINs, or cost breakdowns are included in the solicitation itself. The statement of work, detailed deliverables, technical specifications, and performance requirements for the grant management system are not detailed in the available materials, leaving the scope of the system’s functionality undefined in this public document. The solicitation references required attachments such as the Commonwealth Terms and Conditions, W9 form, EFT form, and essential bid forms, which must be uploaded through the COMMBUYS Attachments tab with appropriate confidentiality markings if applicable. No formal evaluation factors, weights, adjectival ratings, or award methodology (LPTA or best value) are outlined, and the basis of award remains unspecified. There are no explicit packaging, marking, preservation, or MIL-STD requirements; no FOB terms, period of performance dates, or option periods are defined; and no contracting officer, COR, COTR, or payment office information is provided. Representation and certification requirements under Section K, including UEI, size status, or socioeconomic certifications, are not included in the available documents. The only administrative guidance specifies that proposals must be submitted through COMMBUYS using its multi-tab interface and that non-compliance with required forms or failure to mark confidential documents properly may result in disqualification. All contractual clauses

EED01 - Economic Development

POSTED

DEADLINE

LPR Software Configuration and Network OptimizationThe contract involves the configuration and optimization of license plate recognition software to ensure accurate and real-time performance in a government surveillance environment. Key tasks include fine-tuning LPR software settings, calibrating surveillance cameras for optimal image capture under varying lighting and weather conditions, adjusting network parameters to support low-latency data transmission, and implementing performance enhancements to maximize system reliability and recognition accuracy. The work is critical to supporting law enforcement and national security operations through dependable automated vehicle identification. This subcontract is issued under the Ministry of National Security of the Government of Jamaica, with a NAICS code of 541511 indicating it falls within the computer systems design and related services category. The solicitation was posted on July 24, 2026, and the performance location is not specified, suggesting work may be conducted remotely or at multiple sites under the agency’s jurisdiction. The contract emphasizes technical expertise in video analytics, network infrastructure, and real-time data processing to ensure seamless integration with existing security systems. No set-aside provisions or specific point of contact are provided in the public record.

Ministry of National Security

POSTED

DEADLINE

Supplier Diversity Program (SDP) Participation CoordinationThe contract requires a certified diverse business, such as an MBE, WBE, VBE, SDVOBE, or LGBTBE, to partner with a prime contractor to meet a 1% Supplier Diversity Program (SDP) spending obligation under a subcontract arrangement. The engagement is tied to a project managed by the Massachusetts Department of Elementary and Secondary Education, with performance located at Santilli Highway in Everett, Massachusetts, 02149. The business must be properly certified to verify its diverse status and will be expected to deliver services aligned with the NAICS code 541511, which pertains to computer systems design and related services. The opportunity was posted on July 24, 2026, and responses are due by September 1, 2026, at 5:00 PM, with no set-aside designation specified. Participation is focused on fulfilling diversity spend targets rather than direct procurement of goods or services, making coordination and documentation of expenditures critical to compliance.

DOE02148 - Department of Elementary and Secondary Education

POSTED

DEADLINE

in about 1 month

More opportunities from Department Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)

Same awarding agency

Hearing Enhancement through ARtificially Intelligent NeurotechnoloGy (HEARING)The Advanced Research Projects Agency for Health (ARPA-H) is soliciting proposals under the Hearing Enhancement through ARtificially Intelligent NeurotechnoloGy (HEARING) program, identified by solicitation number ARPA-H-SOL-26-154, with a response deadline of August 14, 2026. This initiative seeks to develop a closed-loop neurotechnology system that reads neural activity from the auditory cortex, dynamically modulates incoming sound in real time, and writes back missing auditory information through targeted stimulation, aiming to restore hearing by targeting brain processing rather than mechanical ear function. The work is structured into three tightly integrated Technical Areas: TA1 focuses on creating minimally invasive intracortical devices with recording and stimulation capabilities, TA2 involves developing a wearable, wireless dynamic sound modulator, and TA3 requires designing real-time neuroprocessing algorithms that decode and encode auditory signals using clinical expertise in neurology and audiology. All components must be integrated into a single functional platform, with performance increasing in complexity across three program phases, measured by milestone achievement and intermediary metrics. Proposers must first submit a mandatory solution summary in accordance with Appendix A, followed by a full proposal complying with the format and content requirements outlined in Appendix B, along with all other mandatory attachments including the Cost Proposal Model (Appendix E), Administrative and National Policy Document for Other Transactions (Appendix F), and the Sample Other Transaction Agreement (Appendix G). The evaluation process prioritizes scientific and technical merit, proposer capabilities, potential impact on ARPA-H’s mission and user experience, and cost assessment, with no assigned numerical weights. Proposals must be submitted exclusively through the ARPA-H Solution Submission Portal after registration, written entirely in English, and all proprietary content must be clearly marked as “Proprietary” — the term “Confidential” is prohibited as it is reserved for government national security information. Key eligibility restrictions prohibit FFRDCs, government entities, and employees from participating as prime or sub-performers unless an essential unique capability is substantiated during the solution summary phase; entities from covered foreign countries, foreign entities of concern, participants in malign foreign talent recruitment programs, or those suspended/debarred from government contracting are ineligible. Cost proposals must substantiate labor, materials, and equipment, with backup documentation required for expenses exceeding $15,000. All awardees must maintain active SAM.gov registration, comply with CUI handling standards under 32 CFR §2002, adhere to human

Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

DEADLINE

Restorative and health-Enhancing Sleep Time (REST)The Advanced Research Projects Agency for Health (ARPA-H) is soliciting innovative proposals under the Restorative and health-Enhancing Sleep Time (REST) program to revolutionize sleep health through objective, home-based, closed-loop technologies that detect and respond to sleep microstructures in real time. The program aims to reduce by at least 50% the 10-year risk of chronic diseases linked to poor sleep—including dementia, depression, cardiovascular disease, and type 2 diabetes—by developing validated systems that measure, diagnose, and treat sleep dysfunction with precision. The technical scope is divided into two areas: Technical Area 1 (TA1) focuses on creating in-home systems for objective measurement and mechanistic classification of poor sleep using physiological signals, while Technical Area 2 (TA2) targets the development of integrated, noninvasive, closed-loop interventions that adapt in real time to individual sleep physiology to improve outcomes. The program is structured into three phased milestones over 66 months—Prove Tech (24 months), Proof-of-Concept (18 months), and Translation (24 months)—with specific technical benchmarks including AUC thresholds for insomnia diagnosis, sensitivity/specificity targets for sleep classification, and Pearson correlation standards for fidelity to polysomnography. Key milestones include IRB approvals by month 3, human subject enrollment by month 12, technology validation and FDA submissions by month 39, and final site visits and demonstrations between months 63 and 66. Proposals must be submitted in two stages: a Solution Summary, due by August 12, 2026, at 12pm ET, and a Full Proposal for those invited to proceed. The Solution Summary must be submitted via https://solutions.arpa-h.gov/events, adhere to strict formatting rules including 12-point Avenir Next LT Pro font, and comply with page limits of six pages for single TA or eight pages for both TAs, excluding cover pages, basis of estimate, cost share strategy, and citations. Only invited proposers may submit a Full Proposal, which includes an in-person pitch—45 minutes for one TA or 60 minutes for both—and supporting documentation divided into five volumes: a four-page Technical Proposal, an unrestricted Cost/Price Proposal, a two-page Human or Animal Subjects Research section, a Data Management and Security Plan, and up to five pages of qualifications per key personnel. Evaluation is based on scientific and technical merit, feasibility, innovation, proposer capability, and budget

Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

DEADLINE

Technology InteGrator and AcceleratoR (TIGAR)The Technology InteGrator and AcceleratoR (TIGAR) solicitation, issued by the Advanced Research Projects Agency for Health (ARPA-H) under number ARPA-H-SOL-26-144, seeks innovative solutions to enable temperature-flexible storage of complex regenerative tissues and organs, removing reliance on strictly controlled cryogenic conditions. The effort targets functional preservation of organoids, donated tissues, whole organs, or one-cubic-centimeter tissue volumes for at least 30 days at practical temperatures: -80°C, -20°C, 4°C, or 20°C–25°C room temperature, using novel combinations of materials, AI/ML, high-throughput screening, biological interventions, devices, or packaging approaches. The project is structured as an 18-month period of performance divided into two nine-month phases, with a down-select decision at the end of Phase 1. Proposals must align with HHS health IT standards, promote open-source software licensing (MIT, BSD, Apache 2.0), enhance data interoperability, and avoid low-risk or junior-staffed approaches designed solely for cost appearance. Funding is capped at $2 million per award, and only proposals submitted through the ARPA-H Solution Submission Portal will be considered. The solicitation allows multiple Other Transaction (OT) agreements and does not use a set-aside. Submission follows a two-step process: first, a 7-minute Solution Video with a transcript and supplemental slides, and second, a Full Proposal including technical, management, cost, and administrative documentation. The Solution Video deadline for Intake Group 1 has been amended to August 12, 2026, with the Full Proposal deadline extended to September 17, 2026; Intake Group 2 deadlines remain December 8, 2026, and February 5, 2027, respectively. All materials must be submitted via the ARPA-H portal, in English, using sans-serif 11-point fonts, with file names free of spaces or symbols. Evaluation prioritizes scientific and technical merit, proposer capabilities, alignment with ARPA-H’s mission and user needs, and cost realism. Proposal teams must hold valid SAM.gov registrations with active UEIs, provide good faith representations of intellectual property ownership, disclose organizational conflicts of interest, and ensure compliance with federal research security regulations, including prohibitions against involvement with malign foreign talent programs or entities of concern under the CHIPS and

Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

DEADLINE

Intelligent Generator of Research (IGoR) - ISOThe Intelligent Generator of Research (IGoR) program, issued under solicitation ARPA-H-SOL-26-155 by the Advanced Research Projects Agency for Health (ARPA-H), aims to revolutionize biomedical research by building an AI-enabled interoperable ecosystem that accelerates the development of therapies for complex diseases. Designed as a five-year, three-phase initiative, IGoR seeks to create a closed-loop system comprising mechanistic disease models that capture causal biological relationships across scales, an AI orchestration layer that identifies knowledge gaps and designs optimal experiments, a standardized, reproducible protocol architecture accessible to any qualified lab, and a distributed marketplace of validated laboratories that execute these protocols and return high-quality data. Together, these components aim to produce validated scientific knowledge at least ten times faster than conventional methods, enabling researchers to pursue bold, unconventional directions currently hindered by inefficiency. The program operates under an Other Transaction (OT) Agreement framework governed by a Draft Model OT Agreement, with all terms subject to negotiation by the Government Agreements Officer, and is authorized under 42 U.S.C. § 290c(g)(1)(D). Proposals must fully address four technical areas across all three phases, with Phase III requiring the expansion of the system to a second disease area, operation of a unified experiment marketplace, and public release of all computational artifacts. Proposals must be submitted via the ARPA-H Solutions portal by the extended deadline of August 6, 2026, and must conform to strict formatting guidelines, including English language, 11-point sans-serif font, and 1-inch margins on 8.5 x 11-inch pages. Proposers must register in SAM.gov with an active Unique Entity Identifier (UEI) and designate an Electronic Business Point of Contact, and must include a fully burdened Basis of Estimate covering direct labor, equipment, travel, other direct costs, indirect costs, and profit/fee, with all resource sharing integrated into the total proposed cost. The evaluation will prioritize overall scientific and technical merit, proposer capability, relevance to ARPA-H’s mission, and cost reasonableness, with no fixed weights assigned. Performance is milestone-driven, with payments tied to government verification of successful completion, requiring detailed Task Description Documents (TDDs) specifying quantitative performance criteria. All deliverables must be submitted on schedule and maintained for audit for up to three years post-award. The agreement imposes critical restrictions including prohibition on Covered Telecommunications Equipment under Public Law 115

Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

DEADLINE

Brain Repair of Any Injured Neural Structure (BRAINS)The Advanced Research Projects Agency for Health (ARPA-H) is seeking innovative solutions through the Brain Repair of Any Injured Neural Structure (BRAINS) Exploratory Topic program under solicitation ARPA-H-SOL-26-148, which utilizes Other Transaction (OT) agreements rather than standard federal contract mechanisms. The program aims to advance technologies capable of restoring function to damaged brain regions—specifically targeting areas such as the hippocampus, amygdala, thalamus, hypothalamus, striatum, cingulate cortex, substantia nigra, brainstem, and cerebellum—by generating and engrafting region-specific precursor tissue, while explicitly excluding the neocortex and spinal cord as well as conventional cell or organoid-based approaches. Proposers must submit a mandatory solution summary prior to full proposal submission, with two intake cycles: the first requiring solution summaries by July 9, 2026, and full proposals by August 6, 2026; the second, with deadlines of January 7, 2027, and February 6, 2027, respectively. Proposals must be submitted via the ARPA-H Solution Submission Portal and must conform to a strict three-volume structure: Volume I (Technical and Management Proposal with a 10-page limit for core content), Volume II (Cost Proposal using the ARPA-H Standard Excel Spreadsheet and supporting narrative), and Volume III (Administrative and Policy Requirements including certifications for organizational conflicts of interest, research security, biosecurity, cyber practices, animal research approvals, and tax compliance). Awardees will be evaluated based on the scientific and technical merit of the approach, the proposer’s expertise, potential for clinical and commercial impact aligned with ARPA-H’s mission, and the reasonableness of the proposed cost, with no preset weighting but ranked in descending importance. Phase I awards are anticipated at $500,000 per team with optional Phase II funding up to an additional $500,000, subject to successful technical milestones and budgetary compliance. Financial administration requires registration and invoice submission via the Payment Management Services (PMS) portal, with detailed justifications for each payment tied to specific milestones or TDD tasks, and salary support for individuals is capped at the Executive Level II rate set by the Office of Personnel Management. All awarded work must occur in the United States, with priority given to domestic entities, and proposers must confirm compliance with national security

Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

DEADLINE

Regulatory Strategy and FDA Submission SupportThis contract involves providing specialized regulatory consulting and support services for FDA Center for Devices and Radiological Health (CDRH) submissions related to neuromodulation devices. The scope includes assistance with 510(k) and De Novo regulatory pathways, as well as the preparation and review of design control documentation essential for compliance with FDA requirements. The contract is categorized under NAICS code 541611, indicating management consulting services. Issued by the Advanced Research Projects Agency for Health (ARPA-H), under the Department of Health and Human Services, the opportunity is a subcontract arrangement. The solicitation was posted on June 16, 2026, with responses due by August 12, 2026. While specific geographic details for performance and organizational types are not provided, the contract emphasizes critical support to facilitate FDA approval processes for innovative neuromodulation technologies, underscoring the importance of regulatory expertise in medical device development within a government research framework.

Administrative Management and General Management Consulting Services

POSTED

about 1 month ago

DEADLINE

Clinical Trial Execution and Human Subjects ResearchThis contract involves conducting IRB-approved human subjects research focused on sleep diagnostic and therapeutic systems. It encompasses activities such as subject enrollment, clinical validation, and comprehensive trial management, ensuring rigorous clinical trial execution in line with regulatory standards. The research aims to advance the development and validation of innovative sleep-related technologies through carefully controlled and ethically supervised studies. Issued by the Advanced Research Projects Agency For Health (ARPA-H) under the Department of Health and Human Services, this subcontract falls under the NAICS code 541611, which pertains to administrative management and general management consulting services. The solicitation was posted on June 16, 2026, with a response deadline of August 12, 2026. While specific locations for performance and points of contact are not detailed, the contract carries significance for advancing health research in sleep medicine within the broader federal mission.

Administrative Management and General Management Consulting Services

POSTED

about 1 month ago

DEADLINE

Data Management and Security Plan DevelopmentThe contract entails the development of a secure and compliant data management and security plan specifically designed for handling sensitive physiological and health data within the REST program. This plan must align with federal privacy and data sharing requirements, ensuring that all data management practices comply with relevant standards and regulations. The work is categorized under NAICS code 541512 and is issued as a subcontract opportunity by the Advanced Research Projects Agency for Health (ARPA-H), part of the Department of Health and Human Services. The solicitation was posted on June 16, 2026, and responses are due by August 12, 2026, at 4:00 PM. Although the specific location for performance and point of contact details are not provided, the contract focuses on developing robust frameworks to secure sensitive health data and facilitate compliant sharing protocols across the REST program. This initiative supports the broader goal of advancing research health data protection while enabling effective data collaboration under strict federal guidelines.

Computer Systems Design Services

POSTED

about 1 month ago

DEADLINE

Closed-Loop Neuromodulation System DevelopmentThe contract focuses on the development and validation of closed-loop, non-invasive neuromodulation systems aimed at improving sleep quality for individuals suffering from insomnia. These systems will utilize real-time physiological data to personalize therapeutic interventions, enhancing treatment effectiveness. The effort involves cutting-edge technology integration and aims to provide a tailored approach to neuromodulation that responds dynamically to the patient's physiological signals. Issued by the Advanced Research Projects Agency for Health (ARPA-H) under the Department of Health and Human Services, this subcontract seeks expertise under the NAICS code 334510, covering electromedical and electrotherapeutic apparatus manufacturing. The solicitation was posted on June 16, 2026, with a response deadline of August 12, 2026, emphasizing timely engagement in this innovative health technology initiative. The contract supports advancing personalized, data-driven healthcare solutions to address sleep disorders through sophisticated biomedical engineering.

Electromedical and Electrotherapeutic Apparatus Manufacturing

POSTED

about 1 month ago

DEADLINE

Development of In-Home Sleep Diagnostic SystemsThe contract involves the design and development of advanced, non-invasive diagnostic systems intended for use in the home to monitor sleep physiology. These systems aim to diagnose insomnia and distinguish its various subtypes by analyzing biosignals. The project has critical milestones requiring system validation by the 21st month and full usability in a home environment by the 39th month of the contract period. Issued by the Advanced Research Projects Agency For Health under the Department of Health and Human Services, the subcontract falls under NAICS code 334510, which relates to the manufacture of electronic components and equipment. The solicitation was posted in June 2026, with a response deadline in August 2026. The contract emphasizes cutting-edge technology development with real-world application in healthcare, specifically focusing on improving sleep disorder diagnostics through in-home monitoring solutions.

Electromedical and Electrotherapeutic Apparatus Manufacturing

POSTED

about 1 month ago

DEADLINE

Transition Readiness & Exportable Data SolutionsThe contract focuses on the development of open standards, exportable data formats, and comprehensive transition plans aimed at ensuring future competition and vendor neutrality for the AURORA platform. It involves creating solutions that facilitate interoperability and data portability to prevent vendor lock-in and support a competitive ecosystem. The work is designed to promote sustainable technology adoption and flexibility within the platform's evolving infrastructure. Issued as a subcontract under the Advanced Research Projects Agency for Health (ARPA-H), part of the Department of Health and Human Services, the contract is linked to activities performed in Washington, ZIP code 20005. The associated NAICS code is 541611, which corresponds to administrative management and general management consulting services. This initiative reflects a strategic approach to health technology development, emphasizing readiness for transition and broad data accessibility to enhance innovation and collaboration across stakeholders.

Administrative Management and General Management Consulting Services

POSTED

about 1 month ago

DEADLINE

Cloud Infrastructure & Security ComplianceThis contract involves the management of the cloud infrastructure supporting the AURORA platform, with a strong focus on ensuring scalability, implementing necessary patching, and conducting continuous monitoring. The scope requires maintaining compliance with Federal Risk and Authorization Management Program (FedRAMP) Moderate Authorization to Operate (ATO) standards as well as adherence to the NIST SP 800-53 security controls, underscoring a priority on robust security and regulatory compliance. Issued as a subcontract by the Advanced Research Projects Agency for Health (ARPA-H) under the Department of Health and Human Services, the work is performed in Washington, D.C., ZIP code 20005. The contract falls under the NAICS code 518210, which pertains to data processing, hosting, and related services, and supports the agency's goal of securing and maintaining critical health research infrastructure in accordance with federal cybersecurity requirements.

Computing Infrastructure Providers, Data Processing, Web Hosting, and Related Services

POSTED

about 1 month ago

DEADLINE