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Toxicity evaluation of YC1 in hSULT1A1 and mSULT1A1 mice

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Federal

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The National Institutes of Health is seeking a toxicity evaluation of YC1 to establish its therapeutic window through head-to-head comparisons in mice with humanized SULT1A1 and wild type mouse SULT1A1. This effort is currently managed by GemPharmaTech LLC under contract 75N95025P00413 with a value of 58,936 dollars. The current agreement is a firm fixed price contract that is expected to end on September 23, 2026. Due to the specialized nature of the custom mice required for the study, this opportunity is classified as a likely recompete with medium confidence. The work is performed in Rockville, Maryland, and is managed by the Department of Health and Human Services.

General Info

NIH toxicity evaluation of YC1 by GemPharmaTech LLC, ending September 23, 2026.

Agency

Department Of Health And Human Services → National Institutes Of Health Nida

NAICS

541380 - Testing Laboratories and Services

Place of Performance

Rockville, MD, 20850, USA

Set-Aside

NONE

Documents

0

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Timeline

PostedMar 23

pre-forecast

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health Nida

Contacts2 people available

OfficeBethesda, MD, 20892, USA

Organization / AgencyDepartment Of Health And Human Services → National Institutes Of Health Nida

Office AddressBethesda, MD, 20892, USA

Contacts

Andrew Varley

contact@example.gov

+1 (555) 000-0000

Joshua T. Lazarus

contact@example.gov

+1 (555) 000-0000

Full Description

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Predicted recompete opportunity based on federal award data.
Current Contract: 75N95025P00413 Incumbent: GEMPHARMATECH LLC Contract Value: $58,936 Potential End Date: 2026-09-23T00:00:00.000Z Competition: NOT COMPETED UNDER SAP Pricing: FIRM FIXED PRICE Classification: recompete-likely (Confidence: medium - 55/100)
NCATS seeks to determine if YC1 which works with a unique mechanism of cytotoxicity towards cancer cells that express SULT1A1. In doing so, NCATS shall establish the therapeutic window for YC1. To that end NCATS requires head-to-head comparison on YC1 in mice that have humanized SULT1A1 (custom mice available at GemPharmaTech) and with mouse SULT1A1 (wild type).

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