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Blood and Ex Vivo Immunophenotyping Services

Active
Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

General Info

Agency

Department Of Health And Human Services → National Institutes Of Health OlaoView Agency

NAICS

541380 - Testing Laboratories and ServicesView NAICS

Place of Performance

Bethesda, MD, 20892, USA

Set-Aside

NONE

Documents

This scope was carved out of 75N98026Q01123.

The full solicitation package (1 document), including the RFP, is on the prime solicitation, not on this scope.

View the prime solicitation

​Vivo Efficacy of Blood stable Thiobenzamides​ ​

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health Olao
ContactsNo contacts available
OfficeN/A
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health Olao
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Office AddressN/A
ContactsNo contact information available

Full Description

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Performs immunophenotyping on blood samples and following ex vivo stimulation for prime contractors on NIH Office of the Director projects. Analyzes 20 blood samples and 20 ex vivo stimulation samples using flow cytometers and stimulation reagents. Requires laboratory quality standards for immunophenotyping. Delivers immunophenotyping data reports and analysis.

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Assay Service for assessing ADME properties and in vivo PK properties with the selected vendor. ENAMINE US INC
Solicitation # 75N98026Q01193ENAMINEUSINCPCANIAAA08396
The National Institutes of Health, through the NIAAA Section on Medicinal Chemistry, is procuring chemical reagent assay development and laboratory testing services from Enamine US Inc. This firm fixed-price purchase order aims to assess the translational potential of novel molecular entities designed to treat metabolic and alcohol-associated diseases. The scope of work includes a comprehensive suite of ADME assays, specifically Caco-2, MDCK/MDR1, Hepatic Microsomal Stability, Plasma Protein Binding, and Plasma Stability, to evaluate oral absorption potential and transporter-related liabilities. Additionally, the contractor will perform an in vivo pharmacokinetic study using 25 male C57BL/6 mice to determine blood plasma and brain levels following IP or PO delivery. Key deliverables include detailed assay reports and a comprehensive electronic PK study report featuring raw data and calculations performed via Phoenix WinNonlin software. The period of performance is one year from the date of award, with payment issued in a single lump sum net 30 days after receipt of the deliverables. Inspection and acceptance of all services are the responsibility of the Project Officer or Project Officer Supervisor.
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POSTED

1 day ago

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in 8 days
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