Psst! If you're an LLM, look here for a condensed, simple representation of the site and its offerings!

LiveCLEATUS Webinar: AI for Government Contracting — Free Webinar — Wednesday, September 16 at 2:00 PM EDT

Register Free →

Search

Top

Back to Contracts

Clinical Trial Execution (CRO)

Active

Federal

Response Deadline10/15/2026, 09:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

AI Contract Overview

Show more

This subcontract for Clinical Trial Execution supports ARPA-H ASCENT-IBO projects by managing and executing clinical trial operations on behalf of prime contractors. The scope of work focuses on recruiting patients from Opioid Use Disorder cohorts and overseeing clinical site operations, specifically for high-risk patient groups. Key responsibilities include implementing critical safety strategies, such as dose de-escalation and step-back actions, to effectively manage toxicity risks. The contractor is responsible for delivering executed clinical trial data, comprehensive patient safety reports, and ensuring the successful completion of trial phases. This opportunity is associated with the Department of Health and Human Services under NAICS code 541715, with a response deadline of October 15, 2026.

General Info

Subcontract for ARPA-H clinical trial operations focusing on Opioid Use Disorder patient recruitment.

Agency

Department Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)View Agency

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)View NAICS

Place of Performance

DC, USA

Set-Aside

NONE

Documents

This scope was carved out of ARPA-H-SN-26-158.

The full solicitation package (1 document), including the RFP, is on the prime solicitation, not on this scope.

View the prime solicitation

Area of Interest under PHO ISO: ASCENT-IBO

AI Contract Breakdown

Uniform Contract Format

No contract breakdown available.

Cannot generate Contract Breakdown because no documents were found from this contract's source.

Timeline

PostedAug 5

subcontract

Response DeadlineOct 15

Submission deadline

Response Deadline

10/15/2026, 09:00:00 PM UTCin about 1 month

Ready to pursue this opportunity?

Start your free trial to track this contract, build proposals with AI assistance, and manage your pipeline.

Organization & Contact Information

Show more

AgencyDepartment Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)

ContactsNo contacts available

OfficeN/A

Organization / Agency

Department Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)

View Agency Profile

Office AddressN/A

ContactsNo contact information available

Full Description

Show more

Manages and executes clinical trial operations for prime contractors on ARPA-H ASCENT-IBO projects. Recruits patients from Opioid Use Disorder (OUD) cohorts, implements safety strategies including dose de-escalation and step-back actions, and manages toxicity risks. Oversees clinical site operations and high-risk patient cohorts. Delivers executed clinical trial data, patient safety reports, and trial phase completion.

Similar Contracts

Same NAICS industry code

UAS Flight Test & Demonstration Services

FA2385 USAF Afmc Afrl Pzl Afrl Rskd

POSTED

about 22 hours ago

DEADLINE

in about 2 months

Advanced Capability Research & Development

Missile Defense Agency (mda)

POSTED

about 22 hours ago

DEADLINE

in over 3 years

U.S. Army Contracting Command – Sierra Army Depot (ACC-SIAD) Organic Industrial Base (OIB) Modernization Commercial Solutions Opening (CSO)

Solicitation # W912GY-25-S-C001

The U.S. Army Contracting Command – Sierra Army Depot (ACC-SIAD) has issued Commercial Solutions Opening (CSO) solicitation W912GY-25-S-C001 to modernize its Organic Industrial Base (OIB). This initiative focuses on enhancing the speed of battle and force projection through the procurement of innovative commercial items, technologies, and services. Key priority areas include advanced manufacturing, connected digital enterprises, automation and robotics, digital twins, cybersecurity, and agile or flexible facilities. The program is structured around several continuously open Areas of Interest (AoI), which include logistics and inventory management modernization, airfield maintenance, energy and environmental management, and public-private partnerships. Authorized under DFARS Subpart 212.70 and 10 U.S.C. § 3458, this streamlined acquisition process is open to both traditional and non-traditional defense contractors. The solicitation remains open until June 30, 2030, utilizing a multi-phased evaluation process consisting of solution briefs, presentations or pitches, and commercial solution proposals. Awards are intended to be fixed-price contracts issued under FAR Part 12 Commercial Item Procedures. Eligible respondents must be registered in the System for Award Management (SAM) and the PIEE invoicing system. Specific requirements for individual needs, such as the procurement of a Roll Off Truck under AoI W912GY-26-S-C0001, are managed through separate technical specifications and submission deadlines.

W6QK Siad Contr Office

POSTED

about 22 hours ago

DEADLINE

in almost 4 years

Advanced Driver Assistance Systems (ADAS), on road networks at the Fish and Wildlife Service’s (FWS) National Wildlife Refuges (NWR)

Solicitation # 6913G626Q300038

The Department of Transportation's Volpe National Transportation Systems Center is soliciting a firm-fixed-price purchase order to conduct research on Advanced Driver Assistance Systems (ADAS) performance at U.S. Fish and Wildlife Service National Wildlife Refuges. The primary objective is to evaluate how SAE Level 1-2 automation performs in non-typical environments, specifically focusing on wildlife detection, visitor interaction, and unpaved road conditions. Field testing will occur at one or two selected sites, including the Desert, Neal Smith, and Parker River National Wildlife Refuges. The contractor is responsible for providing all vehicles, data-logging instruments, fuel, power, and software, as no government-furnished property will be provided. The period of performance extends from the date of award through August 15, 2028, though offerors may propose a timeline of up to 24 months. Key deliverables include a Data Management Plan, high-fidelity field data, operational logs, a final technical report, and an executive briefing. Award decisions will be based on the most advantageous offer, considering technical capability, past performance, and price, with technical and performance factors weighted approximately equal to cost. Proposals must include a safety component for risk mitigation and a procurement and instrumentation plan. Invoicing must be processed electronically through the iSupplier DELPHI system using login.gov authentication.

6913G6 Volpe National Transportation System Cntr

POSTED

about 22 hours ago

DEADLINE

Synthetic Training Environment (STE) Virtual Software (VSW)

Solicitation # STE-VSW-26-0006

The Army Contracting Command-Aberdeen Proving Grounds (ACC-APG) Orlando Division, on behalf of the Capability Program Executive Simulation, Training, Test & Threat, is issuing a Call for Solutions (CFS) under the Army Open Solicitation (AOS) for the Synthetic Training Environment (STE) Virtual Software (VSW). This initiative aims to modernize immersive virtual training by addressing gaps in the Reconfigurable Virtual Collective Trainer software baseline. The government is utilizing a Government-as-Integrator model divided into five capability lots, focusing on a platform and application architecture. The primary objectives are to deliver a doctrinal gate to live fire, a true combined arms environment, full mission command concurrency, and an open system architecture with published SDKs and APIs to facilitate rapid integration of future capabilities. The total combined value of all awarded lots is approximately 250 million dollars. The acquisition process follows a phased selection approach based on technical merit, schedule achievability, and relevant experience. Evaluation factors prioritize the technical schedule, specifically the speed to Initial Operating Capability, followed by the technical approach and recent performance within the last three years. The project is eligible for Other Transaction Agreements (OTA) per 10 U.S.C. 4022. A strict organizational conflict of interest firewall is enforced for Lot 5, prohibiting those vendors from participating in Lots 1, 2, or 4. Key milestones include a solution deadline of September 28, 2026, followed by down-select notifications on October 2, 2026, and anticipated awards for Lots 1 through 5 by November 13, 2026. Performance is managed on a sprint-to-sprint basis, requiring signed Certificates of Completion to proceed to subsequent funding milestones.

W6QK Acc-Apg-Orlando

POSTED

about 22 hours ago

DEADLINE

Advanced Research Projects Agency for Health (ARPA-H) Small Business Innovation Research (SBIR)/Small Business Technology Transfer (STTR) Program

Solicitation # 7599226SN106

The Advanced Research Projects Agency for Health (ARPA-H) is soliciting proposals from small business concerns (SBCs) for its Fiscal Year 2026 Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs. The program aims to stimulate technological innovation and increase private sector commercialization of federal research and development. Eligible participants must be for-profit businesses located in the United States with no more than 500 employees. The solicitation focuses on seven high-impact research topics: the development of an annual fertility test, versatile bioadhesives, a universal platform for living adaptive toxin-removal, non-surgical therapies for endometriosis, rapid diagnostics for multi-system autoimmune disease, a virtual human brain for neurosurgical robotics, and the ARPA-H Lineage topic for advancing previously funded technologies. The submission process is structured in two stages. Stage 1 requires a Solution Summary, SBA proof of registration, and various certifications. Stage 2 involves a more detailed submission including a technical presentation, a Task Description Document, a cost proposal, and a key personnel worksheet. Awards are based on technical merit, novelty, team experience, and the path to health outcomes, subject to funding availability and security risk assessments. The program utilizes fixed payment milestones and provides additional Technical and Business Assistance (TABA) funding of up to 6,500 dollars for Phase I and 50,000 dollars for Phase II projects. All proposers must maintain an active SAM.gov registration and adhere to strict marking requirements for proprietary technical data.

Advanced Research Projects Agency For Health (arpa-H)

POSTED

about 22 hours ago

DEADLINE

Connected Vehicle Data Subscription

Solicitation # 693JJ326Q000030

The Federal Highway Administration is seeking a comprehensive Connected Vehicle Dataset subscription to obtain anonymized, high-frequency vehicle telemetry from vehicles manufactured after 2019. This data must be delivered at intervals of one to three seconds across the continental United States to support safety analytics and operational performance evaluations at intersections and interchanges. The contract consists of a nine-month base subscription period with an option for one additional nine-month extension. The government intends to solicit this requirement as a single source from Compass IoT Pty Ltd, citing their proprietary platform and specialized data pipelines as the only means to achieve the required interval fidelity and geographical penetration. While this is not a request for competitive proposals, interested parties may submit capability statements to the primary point of contact, Amy Morrissette, to demonstrate their technical ability to meet these specific parameters.

693JJ3 Acquisition And Grants Mgt

POSTED

about 22 hours ago

DEADLINE

Missile Defense Agency - Advanced Capability Concepts

Solicitation # HQ0860-25-S-C001

The Missile Defense Agency (MDA) has issued solicitation HQ0860-25-S-C001 for its Advanced Capability Concepts program, an ongoing opportunity open from May 9, 2025, to May 8, 2030. The agency seeks innovative concepts, scientific breakthroughs, and prototype demonstrations to enhance the robustness and effectiveness of all Missile Defense System elements. Key focus areas include kinetic and hypersonic defense, command and control battle management, integrated non-kinetic and electronic warfare, and disruptive technologies such as AI/ML, resilient networking, and advanced sensors. This is a two-step process where industry is invited to submit white papers on a rolling basis, which are then evaluated for potential negotiation and award. Submissions must follow strict formatting guidelines, including a 10-page limit for the combined executive summary and program description, and must include a Rough Order of Magnitude cost estimate and a program summary quad chart. Awards may be structured as either FAR-based procurement contracts or Other Transaction (OT) agreements, depending on the offeror's recommendation and eligibility. Evaluation is based on a trade-off process prioritizing technical achievement, research capabilities, and program management. Offerors must maintain active SAM.gov registration, disclose any organizational conflicts of interest, and comply with NIST SP 800-171 for safeguarding controlled unclassified information. Performance is centered in Huntsville, Alabama, though the agency emphasizes rapid development and compressed timelines for the transition of breakthroughs into acquisition programs.

Missile Defense Agency (mda)

POSTED

about 22 hours ago

DEADLINE

in over 3 years

Disruptioneering Program Announcement

Solicitation # DARPA-PA-25-07

The DARPA Defense Sciences Office (DSO) Disruptioneering Program, under solicitation DARPA-PA-25-07, seeks to identify and leverage nascent scientific advances for national security through high-risk, high-payoff research. The program utilizes Disruption Opportunities (DOs) to rapidly investigate new concepts, enabling the initiation of unclassified efforts in less than 120 calendar days from inception. Awards are issued as Other Transaction (OT) agreements for prototype projects under 10 U.S.C. § 4022, focusing on proofs of concept, pilots, and the demonstration of technical or operational utility. Proposals are not submitted to the general program announcement but must be responded to via individual DOs. Selection is based on a weighted evaluation of overall scientific and technical merit, potential contribution to the DARPA mission, and price reasonableness, which serves as a mandatory pass/fail gate. Proposals are evaluated on their own individual merit rather than against each other. Awardees must comply with strict cybersecurity standards, including NIST SP 800-171 for safeguarding Controlled Unclassified Information (CUI) and reporting cyber incidents. Administrative requirements include registration in the Wide Area Workflow (WAWF) for electronic invoicing and the provision of SAM Unique Entity Identifiers. Payments are milestone-driven and contingent upon verification by the DARPA Agreements Officer's Representative.

Defense Advanced Research Projects Agcy

POSTED

about 22 hours ago

DEADLINE

in about 2 months

Solicitation # DARPA-PS-26-127

The Defense Advanced Research Projects Agency (DARPA) Multi X Office is soliciting innovative proposals under solicitation DARPA-PS-26-127, titled Perrseus, to develop microscale ultra-high-vacuum systems (uUHV). The program aims to enable compact cold-atom devices and environmentally-decoupled ultra-high Q microelectromechanical (MEMS) and photonics devices, specifically targeting manufacturable vacuum packages with pressures below 10^-10 mbar. The effort is structured as an Other Transaction for Prototype Agreement under 10 U.S.C. 4022, with an estimated period of performance of 42 months starting January 15, 2027. This includes a three-month Phase 0 for security set-up followed by technical development phases. Proposals are evaluated based on overall scientific and technical merit, potential contribution to the DARPA mission, and budget, price, and schedule. Key requirements include CMMC Level 2 self-assessment and strict adherence to Controlled Unclassified Information (CUI) handling guidelines. The program emphasizes low Size, Weight, and Power (SWaP) and high-volume manufacturability. Awardees must deliver ten functional prototypes and undergo in-person government validation of vacuum metrics. The submission process requires a technical and management volume, a detailed price volume, and an oral presentation, with a final proposal deadline of September 23, 2026.

Defense Advanced Research Projects Agcy

POSTED

about 22 hours ago

DEADLINE

Light Forces Enhancement

Solicitation # WS5642957262

Public Services and Procurement Canada is seeking industry feedback for the Light Forces Enhancement project on behalf of the Department of National Defence and the Canadian Armed Forces. The objective is to acquire new light tactical personnel and cargo carrying capabilities to transport soldiers and equipment across complex terrain that is currently only accessible on foot. This solution aims to reduce the individual combat burden on soldiers by carrying additional supplies and increasing the overall speed, range, and duration of operations. The required capabilities must be powerful and lightweight, suitable for both domestic and expeditionary deployments, including high threat environments. This solicitation, identified by number WS5642957262, was posted on September 11, 2026, with a response deadline of October 16, 2026. The project falls under NAICS code 541715 and is managed by the Department of Public Works and Government Services.

Department of Public Works and Government Services

POSTED

DEADLINE

in about 1 month

R3PEATS Multi-Team Triangulation: Collaborative Cross-Method Approaches to Scientific Discovery (RM1)The R3PEATS Multi-Team Triangulation initiative, managed by the National Institutes of Health under the Department of Health and Human Services, focuses on collaborative cross-method approaches to scientific discovery. This program supports coordinated teams investigating central biomedical research questions using complementary populations, model systems, or methods. A primary objective is to enhance scientific excellence by identifying signal robustness and biological variability while integrating replication directly into the research design. This effort is part of the broader NIH Common Fund program dedicated to Rigor, Replicability, and Reproducibility to Promote Excellence, Accuracy, and Translation in Science. The opportunity is currently listed as a forecast with a posted date of September 11, 2026, and interested parties can contact the R3PEATS Program for further information.

National Institutes Of Health

POSTED

DEADLINE

More opportunities from Department Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)

Same awarding agency

Commercialization Support & Strategy

Administrative Management and General Management Consulting Services

POSTED

DEADLINE

Community-Engaged Health Research

Research and Development in the Social Sciences and Humanities

POSTED

DEADLINE

Biomedical Research & Development

Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

DEADLINE

ARPA-H Emerging Health Innovators (EHI) Initiative Proposers Day

Solicitation # ARPA-H-SN-26-161

The Advanced Research Projects Agency for Health, under the Department of Health and Human Services, has issued Special Notice ARPA-H-SN-26-161 regarding the Emerging Health Innovators Initiative Proposers Day. This event is scheduled for October 13, 2026, and is designed to provide essential information to potential proposers. Interested parties must complete their registration by the deadline of October 12, 2026. The program is managed by the EHI Program Team based in Washington, DC, and further details regarding the event and registration process are available through the attached special notice.

Convention and Trade Show Organizers

POSTED

DEADLINE

in about 1 month

Technical Maintenance and Support ServicesThe Technical Maintenance and Support Services subcontract, issued by the Department of Health and Human Services through the Advanced Research Projects Agency for Health, focuses on the maintenance of specialized research equipment for prime contractors on HHS SBIR/STTR projects. The selected provider must execute maintenance based on specific brand, model, and OEM part numbers, ensuring the use of OEM-certified parts and the delivery of comprehensive maintenance logs and service reports. This opportunity is a total Small Business Set Aside under NAICS code 811310, with the place of performance located in Washington, DC. The solicitation was posted on September 1, 2026, and requires a response by October 1, 2026.

Commercial and Industrial Machinery and Equipment (except Automotive and Electronic) Repair and Maintenance

POSTED

DEADLINE

Specialized Hardware/Product Manufacturing (OEM)This subcontract opportunity with the Department of Health and Human Services, specifically under the Advanced Research Projects Agency for Health, focuses on the specialized manufacturing of custom-fabricated components, medical devices, and technical hardware for prime contractors on HHS SBIR/STTR projects. The selected provider will be responsible for the end-to-end process of design, fabrication, assembly, packaging, and testing, delivering physical hardware along with necessary OEM documentation and test reports. To ensure supply chain security, the provider must supply CAGE and manufacturer codes for risk assessment. The contract is designated as a total Small Business Set Aside under NAICS code 339112, with the place of performance located in Washington, DC. Interested parties must submit their responses by October 1, 2026, following the posting date of September 1, 2026.

Surgical and Medical Instrument Manufacturing

POSTED

DEADLINE

ICT Accessibility & Section 508 Compliance ConsultingThis subcontract opportunity with the Department of Health and Human Services, specifically under the Advanced Research Projects Agency for Health, focuses on ICT accessibility and Section 508 compliance consulting. The selected provider will perform accessibility audits and remediation for ICT products supporting prime contractors on HHS SBIR/STTR projects. Key responsibilities include testing software and hardware against HHS ICT accessibility standards and completing the HHS Section 508 Accessibility Conformance Checklist. The contract requires specialized expertise in Section 508 of the Rehabilitation Act to deliver comprehensive audit reports and conformance checklists. This is a total small business set-aside under NAICS code 541511, with the place of performance located in Washington, DC. The solicitation was posted on September 1, 2026, with a response deadline of October 1, 2026.

Custom Computer Programming Services

POSTED

DEADLINE

Clinical Research Organization (CRO) ServicesThis subcontract for Clinical Research Organization (CRO) Services supports prime contractors on HHS SBIR/STTR research projects under the Advanced Research Projects Agency for Health (arpa-H). The scope of work involves managing clinical trials, recruiting patients, and collecting data, while ensuring strict regulatory compliance for human and animal research. Key deliverables include clinical trial reports, patient data sets, and necessary regulatory submission documentation. The opportunity is designated as a Total Small Business Set Aside under NAICS code 541715. It was posted on September 1, 2026, with a response deadline of October 1, 2026. The place of performance is located in Washington, DC.

Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

DEADLINE

FASTPASS System Integration and Operator InterfaceThe FASTPASS System Integration and Operator Interface subcontract, issued by the Advanced Research Projects Agency for Health under the Department of Health and Human Services, focuses on the development of a unified platform that integrates sensor and imaging components for prime contractors. The project requires the design of a system architecture aimed at minimizing operator intervention and the creation of predictive maintenance algorithms to forecast system degradation. The technical scope includes the implementation of system controllers and human-machine interface software. The primary objective is to deliver a fully integrated prototype system and a functional operator interface that can be operated by port staff with a success rate exceeding 95 percent. This opportunity is categorized under NAICS code 541330, with a response deadline of November 10, 2026. Performance of the contract is centered in the 20005 zip code area.

Engineering Services

POSTED

DEADLINE

in about 2 months

Automated Sample Documentation & Imaging SystemThe Automated Sample Documentation and Imaging System is a subcontract under the Advanced Research Projects Agency for Health within the Department of Health and Human Services. The project focuses on the integration of visual imaging and machine-readable data capture for prime contractors on ARPA-H FASTPASS projects. The primary objective is to develop visual imaging systems that incorporate barcode and QR code scanning to create a data pipeline linking package images to sensor data. Technical execution involves the use of high-resolution industrial cameras and specialized image processing software to deliver a fully integrated imaging and labeling module. This effort falls under NAICS code 541512 and is associated with a performance location in the 20005 zip code. The solicitation was posted on August 20, 2026, with a response deadline of November 10, 2026.

Computer Systems Design Services

POSTED

DEADLINE

in about 2 months

Pharmaceutical Through-Packaging Sensor DevelopmentThis subcontract under the Advanced Research Projects Agency for Health (ARPA-H) focuses on the development and integration of high-specificity sensors for FASTPASS projects. The primary objective is to deliver a functional sensor prototype capable of identifying pharmaceutical ingredients through their packaging. To achieve this, the project will implement X-ray techniques for chemical specificity and Raman spectroscopy to improve penetration through packaging thickness while reducing matrix noise, utilizing high-resolution optical sensors and specialized X-ray emitters and detectors. The development process must strictly adhere to regulatory size, weight, and power (SWaP) metrics to ensure operational viability. This effort is categorized under NAICS code 541715 and is managed by the Department of Health and Human Services. Interested parties must respond by November 10, 2026, for this initiative centered in the 20005 zip code area.

Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

DEADLINE

in about 2 months

Ready to Pursue This Opportunity?

Get AI-powered intelligence on this solicitation and the ones like it

Every page of the solicitation package shredded into a compliance breakdown

AI-powered matching based on your capabilities and past performance

Competitor and incumbent history on the requirement

Automated alerts on amendments, Q&A deadlines, and award

Join 650+ contractors already using CLEATUS