Intelligent Generator of Research (IGoR)
Contract Overview
Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.
AI Contract Overview
The Intelligent Generator of Research (IGoR) program, solicited by ARPA-H under the Department of Health and Human Services, is designed to revolutionize the research process by leveraging AI to create an interoperable research ecosystem. The program focuses on developing mechanistic disease models that capture causal biological relationships, an AI-driven orchestration system to identify knowledge gaps and design experiments, a layered protocol system to ensure reproducibility across laboratories, and a distributed marketplace of validated laboratories that deliver high-quality data. This integrated approach aims to accelerate the research cycle by enabling hypothesis generation, experimentation, and model refinement at a rate at least ten times faster than traditional methods. ARPA-H plans to support this initiative through a hybrid Proposers Day event in early June in the Washington, D.C. area, with additional information forthcoming. The solicitation number for this opportunity is ARPA-H-SOL-26-155, with proposals due by August 6, 2026. The program is open under NAICS code 541715 and does not include any set-aside restrictions. The point of contact for inquiries is available via email, and the official details can be accessed through the SAM.gov platform. This initiative is geared toward enabling researchers to pursue complex and unconventional research directions that are currently limited by speed, complexity, or resource demands.
General Info
Agency
NAICS
Place of Performance
DC, USASet-Aside
Timeline
Response Deadline
Organization & Contact Information
Full Description
Amendment 01 adds Appendix E_Draft Model OT Agreement and provides revisions to Appendix B_Solution Summary Format and Instructions, as highlighted.
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ARPA-H intends to host a hybrid Proposers Day in early June in the Washington, D.C. metro area. Additional information will be posted when it becomes availiable.
The Intelligent Generator of Research (IGoR) program aims to eliminate longstanding inefficiencies in research and accelerate the development of effective therapies for complex diseases by creating an AI-enabled interoperable research ecosystem. IGoR would develop: 1) mechanistic disease models that encode causal biological relationships across scales, 2) an AI orchestration layer that identifies knowledge gaps and designs optimal experiments, 3) a layered protocol architecture that enables any qualified laboratory to execute the same experiment reproducibly, and 4) a distributed marketplace of validated laboratories that execute standardized protocols and return gold-standard data. Together, these components form a cycle of hypothesis generation, experimentation, and model refinement that enables researchers to create validated knowledge at least 10x more rapidly than conventional approaches. Ultimately, IGoR will empower researchers at every level to pursue bold, unconventional research directions that are currently too slow, too complex, or too resource‑intensive.