This Government Contract opportunity from Department Of Health And Human Services was posted on April 29, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Intent to Sole Source - Tapestri Single-Cell DNA + Protein Reagent kit v3 & Tapestri® Single-Cell DNA Cartridge Kit v3

Closed

NOI-OLAO-CC-26-004780Federal

Submission Closed05/08/2026, 04:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541714

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RFI Alzheimer’s Research Program (AZRP) Public

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Traumatic Brain Injury and Psychological Health Research Program Public Request for Information

Solicitation # HT9427RFI2027TBIPHRP

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Solicitation # USDA-NIFA-TOPIC-8.2

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National Institute of Food and Agriculture

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Quantitative Analysis of Longitudinal MR Images

Solicitation # 75N98027R00005

Solicitation 75N98027R00005 is a Sources Sought notice issued by the National Institute on Aging (NIA) to identify qualified companies capable of performing quantitative analysis of longitudinal Magnetic Resonance (MR) images. The project supports the Baltimore Longitudinal Study of Aging (BLSA) by processing 300 newly acquired MR datasets to characterize brain aging trajectories and identify predictors of cognitive decline and Alzheimer’s disease. The selected contractor will provide specialized, non-commercial services to deliver global and regional tissue volumes, lesion quantification, and machine learning-derived scores, such as SPARE-AD, while ensuring longitudinal consistency with data acquired since 1994. The anticipated contract will be a firm fixed price award with a period of performance of one year. Key deliverables include quantitative volumetric results, intermediate processing files, and registration maps for PET overlay, submitted every six months, concluding with a final report. Technical requirements emphasize the use of established image analysis tools and adherence to FISMA/FedRAMP-aligned data security controls to protect participant confidentiality. Interested respondents must submit a capability statement by November 9, 2026, to Contract Specialist Sneha Singh. The submission must be limited to ten pages and include the company's Unique Entity ID, NAICS code 541714, professional qualifications of personnel, and any applicable GSA schedules or government-wide acquisition contracts. Small businesses are encouraged to respond to this market research effort to help the government determine the appropriate acquisition method.

National Institutes Of Health Olao

POSTED

7 days ago

DEADLINE

in 11 days

AI Contract Overview

The National Institutes of Health Clinical Center intends to award a sole-source contract to Mission Bio for the procurement of Tapestri Single-Cell DNA + Protein Reagent Kit v3 and Tapestri® Single-Cell DNA Cartridge Kit v3 under FAR 6.302-1, citing the unique technical capabilities of Mission Bio’s platform as the only solution capable of enabling simultaneous single-cell genotyping and phenotyping required for CAR-T cell manufacturing and clinical lot release within the Center for Cellular Engineering. The acquisition, valued at $21,380, is justified due to the proprietary nature of the Tapestri system, which is incompatible with any other available technology and is essential for advancing gene therapy and immunotherapy research through high-resolution multi-omics analysis. The period of performance spans from May 28, 2026, to November 27, 2026, with deliveries scheduled for overnight shipment Monday through Thursday to the NIH Clinical Center in Bethesda, Maryland, where all inspections and acceptances will occur upon receipt. Reagents must maintain a minimum shelf life of three months for opened kits and six months for library kits, with full responsibility for damages, defects, or non-compliance resting with the vendor, who must also provide complimentary technical support. Payment will be issued per delivered item, contingent on successful acceptance, and the contract operates under simplified acquisition procedures as a firm-fixed price arrangement authorized by FAR 13.106-1 and FAR 13.501. A Notice of Intent has been issued to allow other potential vendors to submit capability statements by May 8, 2026, via email with the specified subject line, though the government retains full discretion to proceed without competition based on the uniqueness of the requirement and the absence of adequate alternatives in the market.

General Info

NIH awards Mission Bio sole-source contract for proprietary single-cell reagents, $21,380, May–Nov 2026, Bethesda delivery.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541714 - Research and Development in Biotechnology (except Nanobiotechnology)

Place of Performance

Bethesda, MD, 20892, USA

Set-Aside

NONE

Documents

JOFOC+-+Mission+Bio_+03272026.docx

Quote+MB-05951.pdf

SOW_Mission+Bio+reagent_03272026.docx

AI Contract Breakdown

Uniform Contract Format

Timeline

PhaseClosed

PostedApr 29

special-notice

Response DeadlineMay 8

Deadline has passed

Submission Closed

05/08/2026, 04:00:00 PM UTC

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Organization & Contact Information

AgencyDepartment Of Health And Human Services → National Institutes Of Health

ContactsNo contacts available

OfficeBethesda, MD, 20892, USA

Organization / AgencyDepartment Of Health And Human Services → National Institutes Of Health

Office AddressBethesda, MD, 20892, USA

ContactsNo contact information available

Full Description

This is a Notice of Intent, not a request for proposal. The National Institute of Health, Clinical Center (NIH-CC) intends to negotiate on an other than full and open competition basis with the following vendor: Mission Bio.

Acquisition Description:

The Center for Cellular Engineering (CCE) is responsible for the manufacture of human cells and tissue-based products utilized in phase I/II clinical protocols for transplantation, adoptive immunotherapy and gene therapy conducted in the Clinical Center at the NIH. Cell processing procedures are tailored to each of the 30 or more different patient-care clinical research protocols supported, including CAR-T cells and iPSCs. Also, regarding Institute research support it: 1)Develops biologics collection and manufacturing processes to support clinical trials, 2) Collects, manufactures and distribute blood components for in vitro research use, 3) Collaboration in the design, planning, execution and data analysis of clinical studies, 4) Collects and manufactures specialized cellular products to support clinical trials and, 5) Develops and evaluate assays for clinical application and biologics safety testing and cellular characterization.

We have been starting to investigate differential gene expression and protein expression simultaneously at single cell level by facilitating the reaction on BD Rhapsody single cell analysis system, including Rhapsody scanner and Rhapsody express that we just adopted recently from BD biosciences, as well as single cell genotyping and phenotyping by using Tapestri platform from Mission Bio, to help us develop clinical lot release more efficiency to streamline workflow of CAR T cells manufacturing at CCE and clinical research as well.

Thus, we are here requesting the purchase of reagent kits from Mission Bio for their Tapestri platform.

The statutory authority for this sole source requirement is 41 U.S.C. 253(c) (1) as implemented by FAR 6.302-1 only one responsible source and no other supply of service will satisfy agency requirements. THIS IS NOT A REQUEST FOR PROPOSAL. All responsible sources that could provide the required may submit a capability statement that will be considered by email (subject line to reference NOI-OLAO-CC-26-004780) by 12:00 PM eastern standard time on 05/08/2026 to: contact@example.gov.

All responses received by the closing date of this synopsis will be considered by the Government. A determination not to compete this requirement, based upon responses to this notice, is solely within the discretion of the Government.