Skip to main contentPsst! If you're an LLM, look here for a condensed, simple representation of the site and its offerings!

LiveFree Webinar — Wednesday, November 11 at 2:00 PM ET

Register Free →
CLEATUS
Get CLEATUS

Undiagnosed Diseases Network (UDN) Diagnostic Research Innovation Center

Active
Grant

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

AI Contract Overview

Show more

The National Institutes of Health, through the NINDS, is forecasting the establishment of a Diagnostic Research Innovation Center to support the next phase of the Undiagnosed Diseases Network. This center will operate as part of a broader ecosystem including the Clinical and Data Coordinating Center, Networks of Diagnostic Excellence, and the NIH Undiagnosed Diseases Program. The primary objective of the center is to advance innovative diagnostic tools and strategies for both genomic and non-genomic conditions, which includes the systematic re-evaluation of unsolved cases from previous network phases. The center will focus on generating and testing diagnostic hypotheses by utilizing advanced sequencing, multi-omics, and gene function studies in animal and human in vitro models. By collaborating with various network stakeholders, the center aims to identify novel disease-associated genes, genomic variants, and new syndromes. This initiative seeks an integrated center featuring investigators with a history of scientific synergy and collaboration. While this is currently a forecast to allow potential applicants time to plan and establish partnerships, formal applications are not yet being solicited.

General Info

NIH forecast for a Diagnostic Research Innovation Center to advance undiagnosed disease tools.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541714 - Research and Development in Biotechnology (except Nanobiotechnology)

Place of Performance

Not specified

Set-Aside

NONE

Documents

0

No documents available

Documents will appear here when they are available.

AI Contract Breakdown

Uniform Contract Format

No documents to break down

The breakdown needs solicitation documents. None were found from this contract's source.

Timeline

Posted

forecast

Ready to pursue this opportunity?

Get full access to track this contract, build proposals with AI assistance, and manage your pipeline.

Organization & Contact Information

Show more
AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUSA
Organization / AgencyDepartment Of Health And Human Services → National Institutes Of Health
Office AddressUSA
Contacts
UDN Program Staff
contact@example.gov

Full Description

Show more

NINDS intends to support a Diagnostic Research Innovation Center (DRIC) for the next phase of the Undiagnosed Diseases Network (UDN). The new Network is expected to include a Clinical and Data Coordinating Center (CDCC), geographically distributed clinical Networks of Diagnostic Excellence (NODEs), the NIH Undiagnosed Diseases Program (UDP), a DRIC, the UDN Foundation, patient advocacy organizations, NIH, and other stakeholders. The DRIC will contribute to the diagnosis of UDN participants, including participating in the systematic re-evaluation of unsolved UDN cases from previous phases of the UDN.

The DRIC is expected to test and advance innovative, new diagnostic tools and strategies for both genomic and non-genomic conditions. Working closely with clinical NODEs, the UDP, the CDCC, and other UDN stakeholders, the DRIC will support the generation and testing of diagnostic hypotheses including providing expertise and resources in advanced sequencing and multi-omics, gene function studies in animal and human in vitro models, and the development of non-genetic diagnostic strategies. Collaborating with the Network, the DRIC will contribute to the discovery of novel disease-associated genes and genomic variants, non-genetic contributors to UDN phenotypes, and the identification of new diseases and syndromes. Support is expected for an integrated center that brings together complementary capabilities and investigators with demonstrated scientific synergy and prior collaboration. 

Applications are not being solicited at this time. This Forecast is being published to provide potential applicants time to plan, establish collaborations, and develop responsive projects.

Similar Contracts

Same NAICS industry code

NAICS: 541714
New
Grant
Genomic Data Generation Center for the Gabriella Miller Kids First Pediatric Research Program (U24 Clinical Trial Not Allowed)
Solicitation # RFA-RM-27-008
The National Institutes of Health, under the Department of Health and Human Services, is seeking applications for Genomic Data Generation Center(s) to support the Gabriella Miller Kids First Pediatric Research Program. The primary objective is the rapid production of high-quality sequence and variant data from human specimens related to pediatric conditions, specifically childhood cancers and congenital anomalies. Required data types include genome-wide, RNA, and long-read DNA and RNA sequencing, as well as chromatin accessibility data and genome-wide methylation profiling. All generated data will be re-processed and harmonized by the Kids First Pediatric Data Resource Center to maintain a public-facing, cloud-based resource for the research community. The NIH Common Fund intends to commit 5 to 6 million dollars annually for a maximum award period of three years, with an award ceiling of 3.5 million dollars. Applications are due by January 8, 2027, and will be evaluated via the NIH peer review system based on significance, investigator qualifications, innovation, and approach. A key requirement is the center's agility to implement new assays within a two-month timeframe. This opportunity is restricted to projects that do not propose clinical trials. Eligible applicants must maintain active registrations in SAM, eRA Commons, and Grants.gov. Awardees must adhere to strict cybersecurity protocols, including multifactor authentication and a 48-hour incident notification window, and comply with federal regulations 42 CFR Part 52 and 2 CFR Part 200. Proposals must include itemized per-sample costs, a minimum sample estimate, and a plan for cost reduction over the award period. All research involving human subjects must comply with 45 CFR Part 46, and a comprehensive Data Management and Sharing Plan is required at the time of application.
National Institutes Of Health

POSTED

1 day ago

DEADLINE

in 2 months
View Details
NAICS: 541714
New
International
Health & Life Sciences Data ProviderThis subcontract opportunity with the Government of Canada seeks a Health and Life Sciences Data Provider to supply medical datasets and health-related information products. The selected provider will support prime contractors on Public Services and Procurement Canada projects by delivering pharmaceutical data, healthcare statistics, and clinical research information, as well as specialized life sciences reports. Interested parties must be capable of entering into a Provider’s Master License Agreement to facilitate the delivery of these datasets. The solicitation is open for responses until March 31, 2027, with the place of performance located within Canada.
Government of Canada / Gouvernement du Canada

POSTED

2 days ago

DEADLINE

in 5 months
View Details
NAICS: 541714
New
Federal
Senior Advisor for Neurotherapeutic Network (Small Molecules)The Senior Advisor for Neurotherapeutic Network (Small Molecules) is a small business set-aside subcontract through the Department of Health and Human Services Omas Strategic Buying Center. The selected consultant will provide executive-level subject matter expertise to prime contractors supporting NIH NINDS Blueprint Neurotherapeutic Network projects. Primary responsibilities include reviewing program operations, offering strategic recommendations for pharmacology-related trials, and leading drug discovery teams focused on small molecules for nervous system conditions. Qualified candidates must possess a PhD in Pharmacology, an MD, or an advanced degree in Organic Chemistry. The role requires the delivery of high-level technical reports, detailed scientific analyses, and formal recommendations to meet project milestones. This opportunity was posted on October 28, 2026, with a response deadline of November 5, 2026, falling under NAICS code 541714.
Omas Strategic Buying Center - Professional Services

POSTED

2 days ago

DEADLINE

in 6 days
View Details
NAICS: 541714
New
Federal
High-throughput Unmasking of Biological Interactomes with Binding Landscape Emulators (HUBBLE)
Solicitation # DARPA-PA-27-01
The High-throughput Unmasking of Biological Interactomes with Binding Landscape Emulators (HUBBLE) program, solicited by the DARPA Biological Technologies Office under DARPA-PA-27-01, seeks to develop an in-silico capability for mapping all protein-protein interactions. The primary objective is to create a comprehensive human interactome hypercatalog capturing over 10 million new interactions, shifting from static biomarkers to dynamic, context-aware interactomes. The utility of this capability will be demonstrated by identifying novel diagnostic and therapeutic targets for traumatic brain injury. Awards will be issued as Other Transaction (OT) for Research agreements with fixed, payable milestones. The program is structured in two phases, with Phase 1 estimated at 12 months and Phase 2 anticipated at 18 months, though current awards are limited to Phase 1. Proposers, including large and small businesses, universities, and research institutions, must submit a maximum six-page unclassified abstract via the Broad Agency Announcement Tool by November 5, 2026, to be considered for an Oral Proposal Package due December 11, 2026. Evaluation is based on technical comprehension, technical ability, and the realism of the cost rough order of magnitude. Prime proposers must be registered in the System for Award Management and demonstrate CMMC Level 1 compliance. Performance will be managed through a Task Description Document and a milestone-based payment schedule, with invoicing processed through the Wide Area Workflow system. Security requirements include the Fundamental Research Risk-Based Security Review Process for all senior and key personnel.
Defense Advanced Research Projects Agcy

POSTED

2 days ago

DEADLINE

in 6 days
View Details
NAICS: 541714
New
Federal
Pharmacology and Pain Drug Development SMEThis subcontract opportunity through the Department of Health and Human Services Omas Strategic Buying Center seeks a subject matter expert in pharmacology and pain to support prime contractors on NIH HEAL Initiative projects. The selected expert will provide executive-level guidance on small molecule and biologic therapeutics, focusing on drug discovery and pharmacology-related trials for nervous system conditions. Key responsibilities include performing strategic programmatic reviews, evaluating milestones, and providing mentorship. The role requires the delivery of strategic recommendations and milestone evaluations through formal committee reports. Performance will take place in Bethesda, and the opportunity is categorized under NAICS code 541714. Interested parties should note the response deadline of November 3, 2026.
Omas Strategic Buying Center - Professional Services

POSTED

3 days ago

DEADLINE

in 4 days
View Details
NAICS: 541714
New
Federal
Precision Prevention & Biological Pathway ResearchThe Precision Prevention and Biological Pathway Research subcontract supports prime contractors on Defense Health Agency Alzheimer’s Research Program projects. The primary objective is to conduct research linking service-related exposures to AD/ADRD biological pathways by quantifying military-relevant risk factors. This technical work involves the use of proteomics tools and genomic sequencing to map these biological pathways, culminating in the delivery of detailed research reports and data. Performance of this contract takes place in Frederick, Maryland, under NAICS code 541714. Due to the nature of the study, the contractor must obtain IRB approval and maintain all necessary Human Subjects Research certifications. Interested parties should note the response deadline of December 4, 2026.
Defense Health Agency

POSTED

3 days ago

DEADLINE

in about 1 month
View Details
NAICS: 541714
New
Federal
Blood-Based Biomarker Validation & ScalingThis subcontract focuses on the validation and scaling of blood-based biomarkers to support prime contractors within the Defense Health Agency Alzheimer’s Research Program. The scope of work involves performing detailed laboratory analysis of blood samples, validating the sensitivity and specificity of assays, and establishing scalable testing protocols. These operations must utilize Simoa equipment and biobanking systems while adhering strictly to GLP standards and maintaining CLIA certification. The project is managed under the Department of Defense and is centered in Frederick, Maryland. The primary objective is the delivery of validated, scalable biomarker assays and protocols to advance research goals. Interested parties should note the response deadline of December 4, 2026, and the classification of the work under NAICS code 541714.
Defense Health Agency

POSTED

3 days ago

DEADLINE

in about 1 month
View Details
NAICS: 541714
New
Federal
RFI Alzheimer’s Research Program (AZRP) Public
Solicitation # HT9427RFI2027AZRP
The Defense Health Agency, through the Congressionally Directed Medical Research Programs, has issued a Request for Information under solicitation number HT9427RFI2027AZRP to gather strategic feedback for the fiscal year 2027 Alzheimer’s Research Program. The primary objective is to identify research focus areas and funding opportunities aimed at mitigating the impact of Alzheimer's and related dementias, specifically those associated with traumatic brain injury, military service, and diverse risks. The program seeks to improve the quality of life for Service Members, Veterans, and their families by funding solution-oriented research, including the development of digital and blood-based biomarkers for early diagnosis and the creation of precision prevention strategies. This action is strictly for information and planning purposes and does not constitute a formal solicitation, request for proposals, or request for quotations. No contracts will be awarded based on this announcement, and FY27 funds have not yet been appropriated. Interested parties from academia, industry, non-profit organizations, and federal agencies are invited to provide feedback via Survey Monkey by December 4, 2026. Respondents are cautioned not to submit proprietary or sensitive information through the survey portal as it cannot be protected. The effort is categorized under NAICS code 541714 and is managed by the Department of Defense in Fort Detrick, Maryland.
Defense Health Agency

POSTED

3 days ago

DEADLINE

in about 1 month
View Details
NAICS: 541714
New
Federal
Traumatic Brain Injury and Psychological Health Research Program Public Request for Information
Solicitation # HT9427RFI2027TBIPHRP
The Defense Health Agency, under the Department of Defense and the Congressionally Directed Medical Research Programs, has issued a Request for Information under solicitation number HT9427RFI2027TBIPHRP. This action is strictly for strategic planning and is not a formal solicitation, request for proposals, or request for quotations. The primary objective is to gather feedback from academia, industry, non-profit organizations, and the public to inform the research focus areas and funding opportunities for the fiscal year 2027 Traumatic Brain Injury and Psychological Health Research Program. The program aims to optimize the prevention, assessment, and treatment of psychological health conditions and traumatic brain injuries to benefit Service Members, Veterans, and the general public. Interested parties are asked to provide input on research gaps and funding priorities, specifically regarding the prevention, screening, diagnosis, and treatment of these conditions. Responses must be submitted via Survey Monkey by December 11, 2026. Because the government cannot protect proprietary or sensitive information submitted through the survey platform, such data should not be included. This inquiry does not commit the program to incorporating the feedback into future funding opportunities, and no contract will be awarded based on this specific announcement. All inquiries regarding this RFI should be directed to Patrick M. Younkins.
Defense Health Agency

POSTED

3 days ago

DEADLINE

in about 1 month
View Details
NAICS: 541714
New
Federal
Request for Proposals (RFP) - BARDA Vaccine Medical Countermeasures for Pandemic Influenza Preparedness & Response
Solicitation # 75A50126R00001_RFP_NPIVS_27
The Biomedical Advanced Research and Development Authority (BARDA) is soliciting proposals for the Vaccine Medical Countermeasures for Pandemic Influenza Preparedness and Response Program. The objective is to maintain a permanent readiness posture against high-threat influenza and other viruses with pandemic potential. Selected contractors will provide essential services, personnel, and facilities to produce vaccines, antigens, and adjuvants, while generating the necessary analytical, nonclinical, clinical, and chemistry, manufacturing, and controls data for FDA submission to support rapid regulatory decisions. To be eligible, offerors must be capable of producing vaccines against influenza strains with pandemic potential and demonstrate success through a U.S. influenza vaccine license or a submitted Biologics License Application. The government intends to award contracts to four offerors based on the Highest Technically Rated Offerors with a Fair and Reasonable Price methodology. Evaluation focuses on capabilities, past performance, and price, with a minimum requirement of a High Confidence rating for technical capabilities. The contract structure consists of a 60-month base period and a 60-month option period, with a minimum guarantee of 50,000 dollars. Key requirements include the development of comprehensive manufacturing and business continuity plans, adherence to strict ASPR security and cybersecurity standards, and the use of the Department of Treasury Invoice Processing Platform for quarterly invoicing. Performance is monitored through a BARDA dose tracker, and final acceptance is triggered by the submission of a final report and updated dose tracking data.
Barda - Aspr / Daappo / Barda Dcma

POSTED

4 days ago

DEADLINE

in 21 days
View Details
NAICS: 541714
New
SBIR / STTR
USDA SBIR/STTR Topic 8.2 — Plant Production and Protection - Biology
Solicitation # USDA-NIFA-TOPIC-8.2
The USDA National Institute of Food and Agriculture is soliciting proposals under Topic 8.2 for Plant Production and Protection - Biology. This initiative focuses on advancing crop production and protection through the development of innovative plant breeding methods, diagnostic technologies for diseases, and the creation of new food and non-food crop plants. Research efforts are directed toward improving plant characteristics to mitigate biotic and abiotic stresses, developing new genotypes for commercial applications, and creating tools to support the health of natural and domesticated pollinators. This opportunity is a total small business set-aside under the SBIR/STTR mandate, restricting eligibility to companies with fewer than 500 employees. Managed by the United States Department of Agriculture, the program is led by Dr. Christopher Philips. Interested parties can find further details and application guidelines through the NIFA website.
National Institute of Food and Agriculture

POSTED

5 days ago

DEADLINE

N/A
View Details
NAICS: 541714
Federal
Quantitative Analysis of Longitudinal MR Images
Solicitation # 75N98027R00005
Solicitation 75N98027R00005 is a Sources Sought notice issued by the National Institute on Aging (NIA) to identify qualified companies capable of performing quantitative analysis of longitudinal Magnetic Resonance (MR) images. The project supports the Baltimore Longitudinal Study of Aging (BLSA) by processing 300 newly acquired MR datasets to characterize brain aging trajectories and identify predictors of cognitive decline and Alzheimer’s disease. The selected contractor will provide specialized, non-commercial services to deliver global and regional tissue volumes, lesion quantification, and machine learning-derived scores, such as SPARE-AD, while ensuring longitudinal consistency with data acquired since 1994. The anticipated contract will be a firm fixed price award with a period of performance of one year. Key deliverables include quantitative volumetric results, intermediate processing files, and registration maps for PET overlay, submitted every six months, concluding with a final report. Technical requirements emphasize the use of established image analysis tools and adherence to FISMA/FedRAMP-aligned data security controls to protect participant confidentiality. Interested respondents must submit a capability statement by November 9, 2026, to Contract Specialist Sneha Singh. The submission must be limited to ten pages and include the company's Unique Entity ID, NAICS code 541714, professional qualifications of personnel, and any applicable GSA schedules or government-wide acquisition contracts. Small businesses are encouraged to respond to this market research effort to help the government determine the appropriate acquisition method.
National Institutes Of Health Olao

POSTED

7 days ago

DEADLINE

in 10 days
View Details

More opportunities from Department Of Health And Human Services → National Institutes Of Health

Same awarding agency

NAICS: 541715
Grant
Prevention and Treatment through a Comprehensive Care Continuum for HIV-affected Adolescents in Resource-Constrained Settings--Implementation Science Network (PATC3H-IN)The Prevention and Treatment through a Comprehensive Care Continuum for HIV-affected Adolescents in Resource Constrained Settings Implementation Science Network (PATC3H-IN) is a National Institutes of Health initiative focused on conducting implementation science research to combat adolescent HIV. By developing and testing scalable, low-resource care delivery models in low- and middle-income countries, the network aims to generate robust evidence on HIV incidence, prevention uptake, and viral suppression. These international studies leverage large adolescent populations and innovative, cost-effective service delivery methods to create practice-ready strategies that can be adapted for marginalized and high-burden populations within the United States. The program addresses critical gaps in the U.S. healthcare system where adolescents face similar barriers to care as those in resource-constrained global settings, including poverty, stigma, and fragmented services. Comprising Clinical Research Centers and a Data and Coordinating Center, PATC3H-IN supports the goals of the Ending the HIV Epidemic in the U.S. initiative by accelerating the translation of resilient and cost-conscious care models into domestic practice. This effort is authorized under the Eunice Kennedy Shriver National Institute of Child Health and Human Development to improve overall care outcomes and prevent new HIV acquisitions among at-risk youth.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

11 days ago

DEADLINE

N/A
View Details
NAICS: 541715
Grant
CAPSTONE Centers for Multidisciplinary Research in Child Abuse and NeglectThe CAPSTONE Centers for Multidisciplinary Research in Child Abuse and Neglect is a forecast opportunity from the National Institutes of Health under the Department of Health and Human Services. This initiative focuses on child sexual abuse as a critical public health issue, aiming to overcome ethical and methodological barriers to better understand and prevent its lifelong developmental and health consequences. The program emphasizes translational research to create measurable public health impacts rather than solely identifying risk factors. The initiative utilizes a collaborative P50 mechanism to establish national resources for high-quality research. Key areas of focus include evaluating intervention efficacy, conducting longitudinal studies on chronic disease outcomes, researching biological embedding, and improving data infrastructure. The program is managed by the Pediatric Trauma and Critical Illness Branch of the Eunice Kennedy Shriver National Institute of Child Health and Human Development.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

11 days ago

DEADLINE

N/A
View Details
NAICS: 541715
Grant
Learning Disabilities Research CentersThe National Institutes of Health, through the Eunice Kennedy Shriver National Institute of Child Health and Human Development, is forecasting an opportunity to support transdisciplinary research centers dedicated to improving outcomes for children and youth with specific learning disabilities in mathematics, reading, and writing. These centers will prioritize enhancing the identification and classification of these disabilities while exploring their genetic and neurobiological foundations and testing innovative screening and intervention methods. Beyond primary research, the funded centers are expected to leverage their infrastructure to collaborate with key stakeholders and provide project-based mentorship for emerging researchers in the field of learning disabilities. This initiative is authorized under several sections of the U.S. Code to advance the understanding and treatment of these developmental challenges.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

11 days ago

DEADLINE

N/A
View Details
NAICS: 541714
Grant
Discovery Gateway to Reproductive Health InnovationThe National Institutes of Health, through the Eunice Kennedy Shriver National Institute of Child Health and Human Development, intends to establish the Discovery Gateway to Reproductive Health Innovation. This initiative aims to create a comprehensive, open-access web-based visualization platform and knowledgebase to advance research on male and female reproductive health issues, including infertility, uterine fibroids, endometriosis, preeclampsia, and preterm birth. By integrating multi-omic, pharmacogenomic, and clinical data, the Gateway seeks to fill critical knowledge gaps and provide the biomedical community with shared infrastructure to identify biomarkers, drug targets, and disease mechanisms. The primary objective of this project is to catalyze the discovery of new treatments and cures while fostering public-private partnerships and the development of commercial products. This effort aligns with recommendations from the Task Force on Research Specific to Pregnant Women and Lactating Women. The opportunity is currently listed as a forecast, with administrative oversight provided by the Obstetric and Pediatric Pharmacology and Therapeutics Branch.
Research and Development in Biotechnology (except Nanobiotechnology)

POSTED

11 days ago

DEADLINE

N/A
View Details
NAICS: 541714
Grant
Testing Centers for Evaluation of Somatic Cell Genome Editing Approaches for Translational Applications (U42 Clinical Trial Not Allowed)The National Institutes of Health is seeking applicants to establish Testing Centers for Evaluation of Somatic Cell Genome Editing Approaches for Translational Applications. These centers will provide essential resources and testing services to the biomedical community to advance the development of genome editing technologies for treating human diseases. By collaborating with NIH-funded investigators, the centers will evaluate the efficacy and safety of delivery technologies, establish editing thresholds to minimize off-target effects, and determine feasibility within various model systems. The initiative emphasizes the creation of in vivo and in vitro research models, with a specific interest in new approach methodologies and human-biology-based models to complement traditional methods. Testing Centers are expected to develop standardized assays and operating procedures to ensure scientific rigor and reproducibility. While focusing on a limited number of initial projects, these centers will build adaptable core systems designed to support a wide range of diseases and offer fee-for-service resources on a local, regional, and national scale.
Research and Development in Biotechnology (except Nanobiotechnology)

POSTED

18 days ago

DEADLINE

N/A
View Details
NAICS: 541715
Grant
Coordinating Center for the Claude D. Pepper Older Americans Independence Centers (OAICs)The National Institute on Aging, under the Department of Health and Human Services, intends to publish a Notice of Funding Opportunity for the Coordinating Center of the Claude D. Pepper Older Americans Independence Centers program. This center will act as a facilitator for site interactions and translate program objectives and findings for scientific and general audiences. The selected entity must possess significant scientific expertise in geriatrics and a proven track record of coordinating complex multi-site projects. This announcement serves as a forecast to allow potential applicants time to establish collaborations before the official solicitation is released. The funding opportunity will utilize the U24 activity code. Interested investigators with expertise in aging research are encouraged to prepare for the upcoming application process.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

18 days ago

DEADLINE

N/A
View Details
NAICS: 541715
Grant
Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD), Research Program (U19 Clinical Trial Optional)The National Institute on Alcohol Abuse and Alcoholism, under the Department of Health and Human Services, intends to issue a Notice of Funding Opportunity to continue the Collaborative Initiative on Fetal Alcohol Spectrum Disorders. This multidisciplinary research consortium focuses on a wide range of studies, including basic, clinical, translational, diagnostic, intervention, and prevention research aimed at addressing the lifelong physical, cognitive, and behavioral impairments caused by prenatal alcohol exposure. The program seeks to support high-priority needs such as improving early identification and diagnosis, validating interventions, and exploring the mechanisms of alcohol teratogenesis to reduce the incidence of these disorders. Successful projects must demonstrate strong integration with the broader consortium through the use of shared resources, coordinated data activities, and multidisciplinary expertise. This forecast indicates a research program where clinical trials are optional.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

25 days ago

DEADLINE

N/A
View Details
NAICS: 541715
Grant
Centers for Research on Neglected Infectious DiseasesThe National Institute of Allergy and Infectious Diseases, under the National Institutes of Health, is establishing the Centers for Research on Neglected Infectious Diseases to combat communicable viral, bacterial, parasitic, and fungal infections. This initiative focuses on the epidemiology, pathogenesis, diagnosis, treatment, and prevention of parasitic neglected infectious diseases within endemic regions. By building sustainable in-country research capacity and expertise, the program aims to identify, contain, and mitigate these diseases at their source to protect global health and reduce the risk of spread within the United States. This opportunity is issued as a forecast by the Department of Health and Human Services and is governed by the Public Health Service Act and Federal Regulations 42 CFR Part 52 and 2 CFR Part 200. Interested parties can coordinate with the Division of Microbiology and Infectious Diseases for further information. The program emphasizes a multidisciplinary approach to research and training to address the substantial morbidity and mortality associated with understudied infectious diseases.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

25 days ago

DEADLINE

N/A
View Details
NAICS: 541715
Grant
HIV Prevention and Alcohol (R61/R33 Clinical Trials Optional)The National Institutes of Health, under the Department of Health and Human Services, is offering a Phased Innovation Award to advance innovative HIV prevention interventions. This funding opportunity utilizes a two-stage R61/R33 structure to move research from initial development and feasibility testing to larger-scale efficacy and implementation studies. The initial R61 phase focuses on the development, refinement, and pilot testing of novel strategies to address critical scientific and operational questions, ensuring readiness for expanded evaluation across diverse populations. Upon the successful completion of R61 milestones, the R33 phase provides support for expanded testing of interventions and implementation strategies. These studies may evaluate the scalability, sustainability, and clinical management of HIV prevention interventions, specifically including integrated approaches that address alcohol use and related comorbidities. Interested parties can contact the HIV/AIDS and Alcohol Research Program for further information.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

30 days ago

DEADLINE

N/A
View Details
NAICS: 541715
Grant
Early to Definitive Clinical Trials (R61/R33 Clinical Trial Required)The National Institutes of Health is forecasting a Notice of Funding Opportunity to solicit applications for early to definitive clinical trials. This initiative seeks proposals testing a wide range of interventions, including drugs, devices, biologics, procedures, and behavioral or social interventions, provided they align with the research missions of the participating NIH Institutes, Centers, and Offices. The funding will utilize a bi-phasic, milestone-driven R61/R33 activity code with a maximum project period of seven years. The R61 phase focuses on planning activities, while the R33 phase supports the actual clinical trial. Although applications are not currently being accepted, this notice serves as an advance alert for investigators with expertise in trial design, implementation, and stakeholder engagement to begin developing collaborations and projects.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

about 1 month ago

DEADLINE

N/A
View Details
NAICS: 541715
Grant
Continuation of the Exceptional Longevity Data Management and Coordinating Center (EL DMCC) (U24 Clinical Trial Not Allowed)The National Institute on Aging intends to issue a single U24 cooperative agreement award to support the continued operation and expansion of the Exceptional Longevity Data Management and Coordinating Center. Serving as the central hub for human longevity translational research, the center integrates deeply phenotyped cohorts and multi-omics datasets to enable cross-cohort analyses and collaborative research. Key responsibilities include data harmonization, the implementation of common data standards, and the management of the ELITE Portal, which provides the research community with secure access to analytical tools and cloud-based computational workspaces. The upcoming funding opportunity will require the Coordinating Center to expand its capabilities in artificial intelligence, machine learning, and the integration of diverse datasets across different species. Future objectives include the development of curated target knowledgebases for therapeutic targets, the enhancement of portal interoperability according to FAIR data principles, and the strengthening of community engagement through specialized training and workshops. This notice serves as a forecast to allow potential applicants to establish collaborations before the official solicitation is released.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

about 1 month ago

DEADLINE

N/A
View Details
NAICS: 541714
Grant
Immune Drivers of Autoimmune DiseaseThe National Institute of Allergy and Infectious Diseases seeks to support the Immune Drivers of Autoimmune Disease network to investigate the triggers and early mechanisms of autoimmunity in humans. The primary goal is to develop tools for risk prediction and staging, identify pre-clinical immune mechanisms, and utilize artificial intelligence and big data to prevent autoimmune diseases. This initiative emphasizes the creation of preclinical cohorts and the use of remote recruitment and sampling to advance medical research. The network will be managed by a Coordinating Center responsible for data harmonization, sample sharing, and the administration of an Infrastructure Opportunity Fund for collaborative research projects. This forecast, issued by the National Institutes of Health under the Department of Health and Human Services, establishes a framework for shared infrastructure and steering committee oversight to identify common pathways and prevention opportunities.
Research and Development in Biotechnology (except Nanobiotechnology)

POSTED

about 1 month ago

DEADLINE

N/A
View Details

Ready to Pursue This Opportunity?

Get AI-powered intelligence on this solicitation and the ones like it

Every page of the solicitation package shredded into a compliance breakdown

AI-powered matching based on your capabilities and past performance

Competitor and incumbent history on the requirement

Automated alerts on amendments, Q&A deadlines, and award

Miguel
Hillary
Keith Deutsch
Christine

Join 750+ contractors already using CLEATUS