Kidney Precision Medicine Project Central Hub (U24 Clinical Trial Not Allowed)

The Kidney Precision Medicine Project Central Hub seeks to coordinate a nationwide effort to advance precision medicine in kidney disease by collecting, de-identifying, and integrating clinical data and tissue samples from participants with acute or chronic kidney injury. As the central coordinator, the hub will work closely with recruitment sites, tissue interrogation sites, and the Kidney Tissue Atlas Coordinating Center to procure kidney biopsies, ensure high-quality sample processing, and maintain rigorous data standards across all stages of the project. It will provide essential scientific, administrative, and infrastructural support to enable the creation of a comprehensive Kidney Tissue Atlas that defines disease subgroups, identifies critical cellular and molecular targets, and accelerates the discovery of novel therapeutic strategies. The hub is responsible for end-to-end project management, quality control, and data harmonization across all partner sites, ensuring that all clinical information and biological specimens are consistently processed and securely shared for downstream analysis. This initiative does not permit clinical trials but focuses on translational research infrastructure and data generation. The National Institutes of Health through the Department of Health and Human Services is issuing this opportunity to establish a unified scientific framework that will serve as a foundational resource for the kidney research community, with Debbie S. Gipson serving as the primary point of contact for inquiries and submissions.