Skip to main contentPsst! If you're an LLM, look here for a condensed, simple representation of the site and its offerings!

LiveFree Webinar — Wednesday, November 11 at 2:00 PM ET

Register Free →
CLEATUS
Get CLEATUS

Limited Competition: Clinical and Translational Science Awards (CTSA) Program: Collaborative and Innovative Acceleration Award

Forecast
Grant

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

AI Contract Overview

Show more

The Clinical and Translational Science Awards (CTSA) Program, managed by the National Institutes of Health under the Department of Health and Human Services, aims to accelerate the transition of scientific discoveries into practical treatments, diagnostics, and health interventions. This specific initiative focuses on the Collaborative and Innovative Acceleration Award, which supports the development of new technologies and models to enhance research impact and speed the delivery of healthcare treatments to the public. This opportunity is structured as a forecast for a limited competition, meaning only eligible organizations will be invited to apply. Funding is authorized under the Public Health Service Act and is subject to standard NIH peer-review processes to ensure only meritorious applications are selected. The program leverages a national network of academic medical centers to provide the necessary infrastructure and expertise to move laboratory discoveries into clinical practice and community health.

General Info

NIH forecasts limited competition for innovative CTSA awards to accelerate translational research and improve public health.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541714 - Research and Development in Biotechnology (except Nanobiotechnology)

Place of Performance

Not specified

Set-Aside

NONE

Documents

0

No documents available

Documents will appear here when they are available.

AI Contract Breakdown

Uniform Contract Format

No documents to break down

The breakdown needs solicitation documents. None were found from this contract's source.

Timeline

PhaseForecast
Posted

forecast

Prepare for this forecast

Research the agency, track this forecast, and prepare your capture plan before the solicitation opens.

Organization & Contact Information

Show more
AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUSA
Organization / AgencyDepartment Of Health And Human Services → National Institutes Of Health
Office AddressUSA
Contacts
Division of Clinical Innovation
contact@example.gov

Full Description

Show more

The purpose of the Congressionally mandated Clinical and Translational Science Award (CTSA) Program is to accelerate the translation of scientific discoveries into treatments, diagnostics, and health interventions that improve patient and public health by funding and coordinating a national network of academic medical centers that provide the infrastructure, expertise, training, and collaboration needed to move discoveries from the laboratory into clinical practice and community health. The purpose of the reissuance of the Collaborative and Innovative Acceleration Award for the CTSA Program Notice of Funding Opportunity (NOFO) is to support the collaborative development of innovative approaches, technologies, or models that synergistically enhance the impact of research, advance translational science, and bring more treatments for all people more quickly. 

Awards are made under the authorization of Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.

This is a Forecast for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Eligibility Section for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding. 

Similar Contracts

Same NAICS industry code

NAICS: 541714
New
Federal
BWA Identification Core & Assay DevelopmentThe BWA Identification Core and Assay Development subcontract, managed under the Department of Defense agency W6QK Acc-Apg, focuses on the creation and supply of core biological detection technology and assays for U.S. Navy EMBD IDS projects. The primary objective is to develop assays capable of identifying toxins, viruses, and bacteria with sensitivity and specificity levels that match laboratory PCR standards. To ensure accuracy, the project utilizes biological agent panels and simulants during the testing phase. The scope of work requires the delivery of a biological detection engine, specialized assay kits, and comprehensive performance data. This effort is categorized under NAICS code 541714 and is slated for performance in Gunpowder. The solicitation was posted on November 6, 2026, with a response deadline set for December 7, 2026.
W6QK Acc-Apg

POSTED

1 day ago

DEADLINE

in 30 days
View Details
NAICS: 541714
New
Federal
Firefox
Solicitation # DARPA-PS-26-137
The Firefox program, managed by the DARPA Biological Technologies Office, is a 36-month, three-phase initiative seeking to develop a 100-channel, non-invasive brain-computer interface with 50-micron spatial and 100-microsecond temporal resolution. The program focuses on two primary technical hurdles: the creation of components for dynamic rastering and scanning of coherent optical signals to target multiple regions of interest, and the development of non-digital data processing architectures capable of handling high data rates and computational burdens. Multiple awards are anticipated, with funding ranging between 4 million and 7 million dollars per award. Awards will be issued as Other Transaction for Prototype agreements under 10 U.S.C. 4022, utilizing a milestone-based payment schedule. The selection process is multi-staged, beginning with an abstract evaluation based on technical comprehension, technical ability, and budget realism, followed by an Oral Presentation Proposal for selected candidates. Proposers must be registered in the System for Award Management and possess a Unique Entity Identifier. Key compliance requirements include adherence to ANSI laser safety limits for human tissue exposure, Cybersecurity Maturity Model Certification, and strict guidelines regarding organizational conflicts of interest and foreign influence risk assessments.
Defense Advanced Research Projects Agcy

POSTED

1 day ago

DEADLINE

in 23 days
View Details
NAICS: 541714
New
Federal
Future Program: Laguna
Solicitation # DARPA-SN-27-15
Special Notice DARPA-SN-27-15, issued by the Defense Advanced Research Projects Agency Biological Technologies Office, serves as a public notification for the forthcoming Laguna program. This notice is intended for information and program planning purposes and does not constitute a formal solicitation for proposals. The program is anticipated to be a 36-month effort focused on the development and demonstration of defense-relevant specialty products formulated from U.S.-produced raw materials. These products must meet or exceed the critical performance requirements of existing military materials. Key deliverables for the program include predictive tools for material properties, life cycle assessments, technoeconomic analyses, and commercialization strategy plans. The primary point of contact for the initiative is Dr. William Mounfield. While this notice provides an overview of research interests, DARPA will not accept submissions at this time. Formal solicitation details and submission instructions will be posted on sam.gov upon release. All communications regarding this notice must remain unclassified.
Defense Advanced Research Projects Agcy

POSTED

2 days ago

DEADLINE

in 23 days
View Details
NAICS: 541714
New
Grant
Leveraging NAMs to understand disease triggers, discover early biomarkers and develop new classes of therapeutic strategies for Type 1 Diabetes (U01 Clinical Trial Not Allowed)The National Institutes of Health is seeking research projects to investigate the initiation and early progression of Type 1 Diabetes using human-relevant New Approach Methodologies. Utilizing human cells, tissues, organoids, and microphysiological systems, the initiative aims to identify early biomarkers and therapeutic targets to prevent significant pancreatic beta cell loss. This effort focuses on combining innovative experimental and computational approaches to uncover the cellular and molecular mechanisms driving the disease. Selected awardees will join the Human Islet Research Network to foster collaboration, share data and tools, and coordinate the use of limited human pancreatic tissues. With total program funding of 12 million dollars and an expected 12 awards, the project is scheduled to begin around November 1, 2027. The overarching goal is to accelerate the translation of research discoveries into practical preventive and treatment strategies through a harmonized, multi-laboratory effort.
National Institutes Of Health

POSTED

3 days ago

DEADLINE

N/A
View Details
NAICS: 541714
New
Grant
Cooperative Agreement for affiliated Partner with Rocky Mountain Cooperative Ecosystem Studies Unit
Solicitation # G27AS00062
The U.S. Geological Survey is seeking a CESU partner through a Cooperative Agreement to improve the efficiency and standardization of Real-Time Quaking Induced Conversion (RT-QuIC) assay data analysis for Chronic Wasting Disease (CWD) surveillance. The project aims to replace subjective interpretation with a robust, automated analytical pipeline. Key deliverables include the development of machine-learning models using LSTM, CNN-LSTM, or hybrid architectures to classify fluorescence curves, the creation of an open-source application using R-Shiny or Streamlit/Python for data ingestion and visualization, and the production of a peer-reviewed publication. To ensure reliability, the partner must perform cross-lab validations across at least three independent laboratories, including the USGS National Wildlife Health Center and the University of Georgia's Southeastern Cooperative Wildlife Disease Research Study. The opportunity has a total program funding and award ceiling of 145,220 dollars, with an anticipated period of performance from April 1, 2027, to March 31, 2032. Applications must be submitted via grants.gov by December 8, 2026, and must be submitted by an Authorized Organization Representative. Proposals are evaluated based on purpose and relevance, technical approach, qualifications and past performance, and budget clarity. Applicants must be registered in SAM.gov and provide a Unique Entity Identifier. The award is governed by DOI and USGS Terms and Conditions, and compliance with various 2 CFR 200 regulations regarding monitoring, reporting, and risk assessment is required.
US Geological Survey

POSTED

3 days ago

DEADLINE

in about 1 month
View Details
NAICS: 541714
New
Grant
Cooperative Agreement for affiliated Partner with Gulf Coast Cooperative Ecosystem Studies Unit
Solicitation # G27AS00064
The U.S. Geological Survey (USGS) Eastern Ecological Science Center is soliciting applications for a cooperative agreement under solicitation G27AS00064 to conduct bioinformatic analysis of avian microbiome metatranscriptomic datasets. This research focuses on the genome assembly-based identification of viruses, prokaryotic, and eukaryotic microorganisms, with a specific emphasis on wildlife and zoonotic pathogens. The project involves analyzing shotgun metatranscriptomic data to identify taxonomic domains and estimate microbial diversity and abundance across various host species, tissues, and geographic regions. Awardees are expected to develop reproducible bioinformatic workflows, collaborate on peer-reviewed publications, and make derived data products available through repositories like ScienceBase or the National Center for Biotechnology Information. The program has a total funding ceiling of 459,000 dollars with one expected award. The anticipated period of performance runs from April 1, 2027, to March 31, 2030. Applications must be submitted via grants.gov by December 7, 2026, and must be submitted by an Authorized Organization Representative. Proposals are evaluated based on purpose and relevance, technical approach, qualifications and past performance, and budget justification. Applicants must be registered in SAM.gov to obtain a Unique Entity Identifier and must provide a signed biographical sketch and current and pending support documentation. Payments will be administered through the Department of the Treasury Automated Standard Application for Payments system.
US Geological Survey

POSTED

3 days ago

DEADLINE

in about 2 months
View Details
NAICS: 541714
New
Federal
Immunohistochemical (IHC) Analysis SupportThe Immunohistochemical (IHC) Analysis Support subcontract, issued by the NASA Shared Services Center, involves providing specialized staining and chemical analysis of sectioned tissue for prime contractors on NASA Space Biosciences projects. The scope of work requires the application of antibodies and reagents to cryo-sectioned slides and the use of fluorescence microscopes and IHC staining stations to evaluate neuronal morphology. Due to the technical nature of the work, specialized training in neuro-histology is required to deliver the final analyzed slides and digital imaging reports. This opportunity is categorized under NAICS code 541714 and is associated with a performance location in zip code 94035. The solicitation was posted on November 4, 2026, with a response deadline of November 9, 2026.
NASA Shared Services Center

POSTED

3 days ago

DEADLINE

in 2 days
View Details
NAICS: 541714
New
Federal
Service request for specimen embedding and sectioning.
Solicitation # 80NSSC27948767Q
The NASA Shared Services Center is seeking custom histology research services to support a Space Biosciences Project evaluating neuronal morphology in mouse brains exposed to radiation, isolation, and simulated microgravity. The scope of work involves planning, preliminary testing, embedding, and cryo-sectioning of specific brain regions, including the substantia nigra, hippocampus, and prefrontal cortex. The contractor must provide slides with sections 15 microns thick, which are to be delivered to Principal Investigator Dr. Joshua Alwood within 90 days after receipt of order. Performance will be located at the NASA Ames Research Center. This procurement is being conducted under FAR Part 12 for commercial items and services, with the government intending to issue a sole source contract to ZYAGEN, identified as the sole provider of the required services. While the agency is currently requesting capability statements from interested organizations by November 9, 2026, to determine if a competitive procurement is feasible, it explicitly states that quotes will not be reviewed or accepted at this stage. Primary coordination for this effort is managed by Cara Craft and Will Garrett.
NASA Shared Services Center

POSTED

3 days ago

DEADLINE

in 2 days
View Details
NAICS: 541714
New
SBIR / STTR
Specialized Bio-Research / Protocol Compliance ConsultantThis subcontract opportunity is for a Specialized Bio-Research / Protocol Compliance Consultant to support research and development projects for the United States Navy and Marine Corps Systems Command. The selected provider will conduct research involving recombinant DNA and human or animal subjects, ensuring all activities are executed according to strict research protocols. Key responsibilities include managing recombinant DNA activities within laboratory facilities and maintaining full compliance with federal, state, and local environmental laws regarding the handling of toxic materials. All work must be performed under the necessary IRB and IACUC approvals, with the final deliverables consisting of experimental data and feasibility reports. The contract is designated as a Total Small Business Set-Aside under NAICS code 541714, specifically targeting firms with fewer than 500 employees in alignment with SBIR/STTR mandates. Interested parties must submit their responses by December 2, 2026. This role is critical for prime contractors requiring specialized expertise in bio-research compliance and the technical execution of complex laboratory protocols within the Department of Defense framework.
United States Navy

POSTED

4 days ago

DEADLINE

in 24 days
View Details
NAICS: 541714
New
SBIR / STTR
Biolab Mirror: Artificial Intelligence / Machine Learning (AI/ML) Digital Twin for Intent Characterization and Bio-Containment Integrity
Solicitation # DTR27TZ02-NV001
The Defense Threat Reduction Agency, under the Department of War, is soliciting proposals for the Biolab Mirror, an AI/ML-driven Digital Twin designed to ensure bio-containment integrity and characterize intent in state-sponsored biological research facilities. The project implements a Physics-to-Mesh Zero Trust architecture that cross-validates digital telemetry from LIMS, SCADA, and BMS logs against unalterable physical and biological laws, such as thermodynamics and metabolic rates. This system aims to detect clandestine pathogen scaling and containment spoofing by identifying coherence failures. Beyond its defensive application, the Biolab Mirror will serve as a cyber-physical sandbox for simulating multi-domain attacks against high-containment infrastructure, filling a critical gap in current cyber-range emulation. This is a phased STTR program with a total small business set-aside. Phase I focuses on delivering a conceptual architecture and a working software prototype, while Phase II, with a ceiling price of 1.5 million dollars, involves full project effort over a 24-month duration. Proposals are evaluated based on technical merit, investigator qualifications, and commercial potential. Applicants must be registered in SAM and the SBA Company Registry. Compliance requirements include CMMC standards for safeguarding controlled unclassified information and strict adherence to organizational conflict of interest disclosures. Proposals must be submitted via the DSIP portal by January 6, 2026.
Defense Threat Reduction Agency

POSTED

4 days ago

DEADLINE

in about 2 months
View Details
NAICS: 541714
New
Grant
Systems Biology of Infection and Inflammation in Chronic Diseases (U19 Clinical Trial Not Allowed)
Solicitation # RFA-AI-28-014
The National Institutes of Health (NIH) issued solicitation RFA-AI-28-014 to establish centers focused on the systems-level understanding of the links between infectious pathogens, inflammatory pathways, and chronic diseases. The program supports two types of centers: Chronic and Infectious Diseases Systems Biology Centers (CIDSB), which examine the bidirectional link between chronic and infectious diseases, and Systems Biology Inflammation Centers (SBI), which focus on the role of inflammation in chronic diseases to identify precision medicine targets. The primary goals are to develop predictive computational models for disease progression, discover novel drug targets and biomarkers, and create harmonized, FAIR-compliant cross-disease datasets. The total program funding is 26 million dollars, with an expected 10 awards and an individual award ceiling of 2.5 million dollars. Applications must be submitted electronically via Grants.gov by February 18, 2027. The proposal structure is multi-component, requiring an overall section, an administrative core, a data and modeling core, and a biospecimen collection and processing core, with additional requirements for research projects and optional cores depending on the center type. Evaluation is based on an overall impact score focusing on significance and the qualifications of the investigators. Awardees must comply with strict cybersecurity incident reporting requirements, notifying the HHS awarding agency within 48 hours of discovery, and must adhere to rigorous biosafety and human subjects protection standards. Applicants must maintain active SAM registration and UEI identifiers to be eligible for funding.
National Institutes Of Health

POSTED

4 days ago

DEADLINE

in 3 months
View Details
NAICS: 541714
New
Grant
Systems Biology of Infection and Inflammation in Chronic Diseases (U19 Clinical Trial Not Allowed)
Solicitation # RFA-AI-28-014
The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, is seeking proposals under solicitation RFA-AI-28-014 for the Systems Biology of Infection and Inflammation in Chronic Diseases. This initiative aims to advance the systems-level understanding of how infectious pathogens and inflammatory pathways contribute to the predisposition, onset, and progression of chronic diseases. The program emphasizes the integration of clinical and patient data, large-scale omics datasets, and advanced artificial intelligence and computational modeling to develop strategies for preventing, treating, and mitigating the combined effects of these conditions. This federal solicitation was posted on November 4, 2026, with a response deadline of February 19, 2027. It is important to note that clinical trials are not allowed under this specific funding opportunity. Interested parties can find further details through the provided grants portal.
National Institute Of Allergy And Infectious Diseases

POSTED

4 days ago

DEADLINE

in 3 months
View Details

More opportunities from Department Of Health And Human Services → National Institutes Of Health

Same awarding agency

NAICS: 541715
Grant
Prevention and Treatment through a Comprehensive Care Continuum for HIV-affected Adolescents in Resource-Constrained Settings--Implementation Science Network (PATC3H-IN)The Prevention and Treatment through a Comprehensive Care Continuum for HIV-affected Adolescents in Resource Constrained Settings Implementation Science Network (PATC3H-IN) is a National Institutes of Health initiative focused on conducting implementation science research to combat adolescent HIV. By developing and testing scalable, low-resource care delivery models in low- and middle-income countries, the network aims to generate robust evidence on HIV incidence, prevention uptake, and viral suppression. These international studies leverage large adolescent populations and innovative, cost-effective service delivery methods to create practice-ready strategies that can be adapted for marginalized and high-burden populations within the United States. The program addresses critical gaps in the U.S. healthcare system where adolescents face similar barriers to care as those in resource-constrained global settings, including poverty, stigma, and fragmented services. Comprising Clinical Research Centers and a Data and Coordinating Center, PATC3H-IN supports the goals of the Ending the HIV Epidemic in the U.S. initiative by accelerating the translation of resilient and cost-conscious care models into domestic practice. This effort is authorized under the Eunice Kennedy Shriver National Institute of Child Health and Human Development to improve overall care outcomes and prevent new HIV acquisitions among at-risk youth.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

19 days ago

DEADLINE

N/A
View Details
NAICS: 541715
Grant
CAPSTONE Centers for Multidisciplinary Research in Child Abuse and NeglectThe CAPSTONE Centers for Multidisciplinary Research in Child Abuse and Neglect is a forecast opportunity from the National Institutes of Health under the Department of Health and Human Services. This initiative focuses on child sexual abuse as a critical public health issue, aiming to overcome ethical and methodological barriers to better understand and prevent its lifelong developmental and health consequences. The program emphasizes translational research to create measurable public health impacts rather than solely identifying risk factors. The initiative utilizes a collaborative P50 mechanism to establish national resources for high-quality research. Key areas of focus include evaluating intervention efficacy, conducting longitudinal studies on chronic disease outcomes, researching biological embedding, and improving data infrastructure. The program is managed by the Pediatric Trauma and Critical Illness Branch of the Eunice Kennedy Shriver National Institute of Child Health and Human Development.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

19 days ago

DEADLINE

N/A
View Details
NAICS: 541715
Grant
Learning Disabilities Research CentersThe National Institutes of Health, through the Eunice Kennedy Shriver National Institute of Child Health and Human Development, is forecasting an opportunity to support transdisciplinary research centers dedicated to improving outcomes for children and youth with specific learning disabilities in mathematics, reading, and writing. These centers will prioritize enhancing the identification and classification of these disabilities while exploring their genetic and neurobiological foundations and testing innovative screening and intervention methods. Beyond primary research, the funded centers are expected to leverage their infrastructure to collaborate with key stakeholders and provide project-based mentorship for emerging researchers in the field of learning disabilities. This initiative is authorized under several sections of the U.S. Code to advance the understanding and treatment of these developmental challenges.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

19 days ago

DEADLINE

N/A
View Details
NAICS: 541714
Grant
Discovery Gateway to Reproductive Health InnovationThe National Institutes of Health, through the Eunice Kennedy Shriver National Institute of Child Health and Human Development, intends to establish the Discovery Gateway to Reproductive Health Innovation. This initiative aims to create a comprehensive, open-access web-based visualization platform and knowledgebase to advance research on male and female reproductive health issues, including infertility, uterine fibroids, endometriosis, preeclampsia, and preterm birth. By integrating multi-omic, pharmacogenomic, and clinical data, the Gateway seeks to fill critical knowledge gaps and provide the biomedical community with shared infrastructure to identify biomarkers, drug targets, and disease mechanisms. The primary objective of this project is to catalyze the discovery of new treatments and cures while fostering public-private partnerships and the development of commercial products. This effort aligns with recommendations from the Task Force on Research Specific to Pregnant Women and Lactating Women. The opportunity is currently listed as a forecast, with administrative oversight provided by the Obstetric and Pediatric Pharmacology and Therapeutics Branch.
Research and Development in Biotechnology (except Nanobiotechnology)

POSTED

19 days ago

DEADLINE

N/A
View Details
NAICS: 541714
Grant
Testing Centers for Evaluation of Somatic Cell Genome Editing Approaches for Translational Applications (U42 Clinical Trial Not Allowed)The National Institutes of Health is seeking applicants to establish Testing Centers for Evaluation of Somatic Cell Genome Editing Approaches for Translational Applications. These centers will provide essential resources and testing services to the biomedical community to advance the development of genome editing technologies for treating human diseases. By collaborating with NIH-funded investigators, the centers will evaluate the efficacy and safety of delivery technologies, establish editing thresholds to minimize off-target effects, and determine feasibility within various model systems. The initiative emphasizes the creation of in vivo and in vitro research models, with a specific interest in new approach methodologies and human-biology-based models to complement traditional methods. Testing Centers are expected to develop standardized assays and operating procedures to ensure scientific rigor and reproducibility. While focusing on a limited number of initial projects, these centers will build adaptable core systems designed to support a wide range of diseases and offer fee-for-service resources on a local, regional, and national scale.
Research and Development in Biotechnology (except Nanobiotechnology)

POSTED

26 days ago

DEADLINE

N/A
View Details
NAICS: 541715
Grant
Coordinating Center for the Claude D. Pepper Older Americans Independence Centers (OAICs)The National Institute on Aging, under the Department of Health and Human Services, intends to publish a Notice of Funding Opportunity for the Coordinating Center of the Claude D. Pepper Older Americans Independence Centers program. This center will act as a facilitator for site interactions and translate program objectives and findings for scientific and general audiences. The selected entity must possess significant scientific expertise in geriatrics and a proven track record of coordinating complex multi-site projects. This announcement serves as a forecast to allow potential applicants time to establish collaborations before the official solicitation is released. The funding opportunity will utilize the U24 activity code. Interested investigators with expertise in aging research are encouraged to prepare for the upcoming application process.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

26 days ago

DEADLINE

N/A
View Details
NAICS: 541715
Grant
Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD), Research Program (U19 Clinical Trial Optional)The National Institute on Alcohol Abuse and Alcoholism, under the Department of Health and Human Services, intends to issue a Notice of Funding Opportunity to continue the Collaborative Initiative on Fetal Alcohol Spectrum Disorders. This multidisciplinary research consortium focuses on a wide range of studies, including basic, clinical, translational, diagnostic, intervention, and prevention research aimed at addressing the lifelong physical, cognitive, and behavioral impairments caused by prenatal alcohol exposure. The program seeks to support high-priority needs such as improving early identification and diagnosis, validating interventions, and exploring the mechanisms of alcohol teratogenesis to reduce the incidence of these disorders. Successful projects must demonstrate strong integration with the broader consortium through the use of shared resources, coordinated data activities, and multidisciplinary expertise. This forecast indicates a research program where clinical trials are optional.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

about 1 month ago

DEADLINE

N/A
View Details
NAICS: 541715
Grant
Centers for Research on Neglected Infectious DiseasesThe National Institute of Allergy and Infectious Diseases, under the National Institutes of Health, is establishing the Centers for Research on Neglected Infectious Diseases to combat communicable viral, bacterial, parasitic, and fungal infections. This initiative focuses on the epidemiology, pathogenesis, diagnosis, treatment, and prevention of parasitic neglected infectious diseases within endemic regions. By building sustainable in-country research capacity and expertise, the program aims to identify, contain, and mitigate these diseases at their source to protect global health and reduce the risk of spread within the United States. This opportunity is issued as a forecast by the Department of Health and Human Services and is governed by the Public Health Service Act and Federal Regulations 42 CFR Part 52 and 2 CFR Part 200. Interested parties can coordinate with the Division of Microbiology and Infectious Diseases for further information. The program emphasizes a multidisciplinary approach to research and training to address the substantial morbidity and mortality associated with understudied infectious diseases.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

about 1 month ago

DEADLINE

N/A
View Details
NAICS: 541715
Grant
HIV Prevention and Alcohol (R61/R33 Clinical Trials Optional)The National Institutes of Health, under the Department of Health and Human Services, is offering a Phased Innovation Award to advance innovative HIV prevention interventions. This funding opportunity utilizes a two-stage R61/R33 structure to move research from initial development and feasibility testing to larger-scale efficacy and implementation studies. The initial R61 phase focuses on the development, refinement, and pilot testing of novel strategies to address critical scientific and operational questions, ensuring readiness for expanded evaluation across diverse populations. Upon the successful completion of R61 milestones, the R33 phase provides support for expanded testing of interventions and implementation strategies. These studies may evaluate the scalability, sustainability, and clinical management of HIV prevention interventions, specifically including integrated approaches that address alcohol use and related comorbidities. Interested parties can contact the HIV/AIDS and Alcohol Research Program for further information.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

about 1 month ago

DEADLINE

N/A
View Details
NAICS: 541715
Grant
Early to Definitive Clinical Trials (R61/R33 Clinical Trial Required)The National Institutes of Health is forecasting a Notice of Funding Opportunity to solicit applications for early to definitive clinical trials. This initiative seeks proposals testing a wide range of interventions, including drugs, devices, biologics, procedures, and behavioral or social interventions, provided they align with the research missions of the participating NIH Institutes, Centers, and Offices. The funding will utilize a bi-phasic, milestone-driven R61/R33 activity code with a maximum project period of seven years. The R61 phase focuses on planning activities, while the R33 phase supports the actual clinical trial. Although applications are not currently being accepted, this notice serves as an advance alert for investigators with expertise in trial design, implementation, and stakeholder engagement to begin developing collaborations and projects.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

about 1 month ago

DEADLINE

N/A
View Details
NAICS: 541715
Grant
Continuation of the Exceptional Longevity Data Management and Coordinating Center (EL DMCC) (U24 Clinical Trial Not Allowed)The National Institute on Aging intends to issue a single U24 cooperative agreement award to support the continued operation and expansion of the Exceptional Longevity Data Management and Coordinating Center. Serving as the central hub for human longevity translational research, the center integrates deeply phenotyped cohorts and multi-omics datasets to enable cross-cohort analyses and collaborative research. Key responsibilities include data harmonization, the implementation of common data standards, and the management of the ELITE Portal, which provides the research community with secure access to analytical tools and cloud-based computational workspaces. The upcoming funding opportunity will require the Coordinating Center to expand its capabilities in artificial intelligence, machine learning, and the integration of diverse datasets across different species. Future objectives include the development of curated target knowledgebases for therapeutic targets, the enhancement of portal interoperability according to FAIR data principles, and the strengthening of community engagement through specialized training and workshops. This notice serves as a forecast to allow potential applicants to establish collaborations before the official solicitation is released.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

about 1 month ago

DEADLINE

N/A
View Details
NAICS: 541714
Grant
Immune Drivers of Autoimmune DiseaseThe National Institute of Allergy and Infectious Diseases seeks to support the Immune Drivers of Autoimmune Disease network to investigate the triggers and early mechanisms of autoimmunity in humans. The primary goal is to develop tools for risk prediction and staging, identify pre-clinical immune mechanisms, and utilize artificial intelligence and big data to prevent autoimmune diseases. This initiative emphasizes the creation of preclinical cohorts and the use of remote recruitment and sampling to advance medical research. The network will be managed by a Coordinating Center responsible for data harmonization, sample sharing, and the administration of an Infrastructure Opportunity Fund for collaborative research projects. This forecast, issued by the National Institutes of Health under the Department of Health and Human Services, establishes a framework for shared infrastructure and steering committee oversight to identify common pathways and prevention opportunities.
Research and Development in Biotechnology (except Nanobiotechnology)

POSTED

about 1 month ago

DEADLINE

N/A
View Details

Prepare for this forecast

Research this forecast and prepare for the solicitation

Every page of the solicitation package shredded into a compliance breakdown

AI-powered matching based on your capabilities and past performance

Competitor and incumbent history on the requirement

Automated alerts on amendments, Q&A deadlines, and award

Miguel
Hillary
Keith Deutsch
Christine

Join 750+ contractors already using CLEATUS