Limited Competition: High Impact Specialized Innovation Programs in Clinical and Translational Science
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The Congressionally mandated Clinical and Translational Science Award Program aims to accelerate the translation of scientific discoveries into practical health solutions by funding a national network of academic medical centers that provide the infrastructure, expertise, training, and collaborative environment necessary to move research from the laboratory into clinical practice and community health. Within this program, the High Impact Specialized Innovation Programs are designed to support unique, high-value capabilities, research platforms, or resources that address critical gaps or persistent roadblocks in clinical and translational science at designated CTSA hubs. These initiatives are intended to deliver timely, transformative advances that enhance the overall efficiency and impact of the CTSA network. Awards under this forecast are authorized under Sections 301 and 405 of the Public Health Service Act and governed by federal regulations including 42 CFR Part 52 and 2 CFR Part 200. This is a limited competition forecast, meaning only pre-eligible organizations may apply, and applications will undergo NIH’s standard peer-review process. Only those deemed meritorious will be considered for funding. The National Institutes of Health, through the Department of Health and Human Services and the Division of Clinical Innovation at NCATS, is soliciting applications with a forecast date of July 20, 2026, and inquiries should be directed to the provided point of contact.
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The purpose of the Congressionally mandated Clinical and Translational Science Award (CTSA) Program is to accelerate the translation of scientific discoveries into treatments, diagnostics, and health interventions that improve patient and public health by funding and coordinating a national network of academic medical centers that provide the infrastructure, expertise, training, and collaboration needed to move discoveries from the laboratory into clinical practice and community health. The purpose of the High Impact Specialized Innovation Programs (SIPs) is to support the development and demonstration of unique hub capabilities, research platforms and/or resources to address in a timely manner critical gap areas and/or roadblocks in clinical and translational science at awarded CTSA Program Hubs.
Awards are made under the authorization of Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.
This is a Forecast for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Eligibility Section for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.
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