Opportunities for Collaborative Research with the NIH Intramural Research Program (U01 Clinical Trial Optional)

The program aims to foster collaborative translational research between NIH intramural scientists and external extramural investigators to accelerate the translation of basic biological discoveries into clinical applications that improve health. It supports high-quality science with the potential to advance understanding of significant disease processes or lead to new diagnostics, therapeutics, or prevention strategies aligned with the priorities of participating NIH Institutes and Centers. The initiative specifically encourages partnerships that leverage the unique resources and expertise available within the NIH intramural research program, enabling extramural researchers to conduct clinical research in collaboration with NIH scientists. This effort is designed to strengthen translational science by bridging the gap between laboratory-based research and clinical implementation through integrated, multidisciplinary teams. The funding opportunity, titled Opportunities for Collaborative Research with the NIH Intramural Research Program (U01 Clinical Trial Optional), is posted by the National Institutes of Health under the Department of Health and Human Services and is forecasted for release on July 16, 2026. It is open to both intramural and extramural investigators and allows for clinical trials as optional components. The primary point of contact for inquiries is the U01 Program team, reachable via email at nihirppartnerships@mail.nih.gov or by phone at 301-496-4121. Additional details and application information can be accessed through the Grants.gov portal at the provided link. The program does not specify a set-aside type, NAICS code, or physical office location, reflecting its national scope and administrative structure under NIH's broader research framework.