Mechanistic Toxicology of METALS: Metal Exposure, Transport, Action, Localization, and Susceptibility (RP1 Clinical Trial Not Allowed)

The National Institutes of Health, under the Department of Health and Human Services, is offering a funding opportunity titled Mechanistic Toxicology of METALS: Metal Exposure, Transport, Action, Localization, and Susceptibility. This forecast focuses on supporting mechanistic research to determine how exposure to metals and metal-containing compounds affects biological processes related to human health. Priority is given to studies exploring the absorption, distribution, transport, and mechanisms of action of metals, specifically regarding their impact on immune homeostasis, the central nervous system, and the placental barrier. Eligible research may utilize human biospecimens, computational approaches, experimental models, or new approach methodologies to test defined mechanistic hypotheses. This specific opportunity does not allow for clinical trials. Interested parties can find further details through the provided grants.gov link or by contacting the designated point of contact.