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Mechanistic Toxicology of METALS: Metal Exposure, Transport, Action, Localization, and Susceptibility (RP1 Clinical Trial Not Allowed)

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Contract Overview

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The National Institutes of Health, under the Department of Health and Human Services, is offering a funding opportunity titled Mechanistic Toxicology of METALS: Metal Exposure, Transport, Action, Localization, and Susceptibility. This forecast focuses on supporting mechanistic research to determine how exposure to metals and metal-containing compounds affects biological processes related to human health. Priority is given to studies exploring the absorption, distribution, transport, and mechanisms of action of metals, specifically regarding their impact on immune homeostasis, the central nervous system, and the placental barrier. Eligible research may utilize human biospecimens, computational approaches, experimental models, or new approach methodologies to test defined mechanistic hypotheses. This specific opportunity does not allow for clinical trials. Interested parties can find further details through the provided grants.gov link or by contacting the designated point of contact.

General Info

NIH funding for mechanistic research on metal exposure and its impact on human health.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

Not specified

Set-Aside

NONE

Documents

0

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Timeline

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forecast

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUSA
Organization / AgencyDepartment Of Health And Human Services → National Institutes Of Health
Office AddressUSA
Contacts
contact@example.gov

Full Description

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The purpose of this funding opportunity is to support mechanistic research to understand how exposure to metals and metal-containing compounds alters biological processes relevant to human health. Of particular interest are studies that elucidate the absorption, distribution, transport, cellular trafficking, biological interactions, and mechanisms of action of metals, including mechanisms through which metals may alter immune homeostasis, cross the placental barrier, or gain access to and affect the central nervous system. Studies may employ experimental models, new approach methodologies, computational approaches, or leverage human biospecimens where these approaches are used to address defined mechanistic hypotheses.

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