NIDA Avenir Program: Fundamental Mechanistic Research in Addiction Science
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The NIDA Avenir Program is a forecast initiative by the National Institutes of Health designed to support exceptionally creative early stage investigators in launching innovative research programs within addiction science. The program focuses on bold, high-risk, high-reward mechanistic research across various disciplines, including genetic, molecular, cellular, and cognitive processes relevant to Substance Use Disorders. It specifically targets new investigators, including those from outside the addiction field, who may lack the preliminary data required for standard R01 applications but demonstrate strong potential for leadership in fundamental science. Applicants are encouraged to propose novel, unconventional, or interdisciplinary approaches utilizing wet-lab or data science methods to advance the understanding of SUD mechanisms. This initiative is administered by the National Institute on Drug Abuse under the Department of Health and Human Services, with the primary goal of catalyzing high-impact research and developing the next generation of leaders in the field.
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Avenir, the French word for "future," reflects NIDA's commitment to developing the next generation of leaders in addiction science. Since 2015, the Avenir Program has supported exceptionally creative early stage investigators (ESIs) in launching innovative research programs. NIDA is now expanding this program to support bold mechanistic research across a broader range of addiction science, including genetic, epigenetic, molecular, cellular, circuit, chemical, pharmacological, behavioral, and cognitive processes relevant to Substance Use Disorders (SUDs).
This initiative is intended to catalyze high-risk, high-reward research and attract outstanding new investigators, including those from outside the addiction field. Applications proposing novel, unconventional, or interdisciplinary wet-lab and/or data science approaches to advance understanding of the mechanisms underlying SUDs are encouraged. The Avenir Program is designed for ESIs who may lack the preliminary data needed for an R01 application but propose high-impact research and show strong potential to become future leaders in fundamental mechanistic addiction science.
Grant authorities that allow NIDA to forecast this opportunity are 42 U.S.C. §§ 241 and 284.
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