NIH Specialized Center Grant (Parent P50)
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The NIH Specialized Center Grant (Parent P50) supports investigator-initiated, multidisciplinary research programs centered on a major scientific theme or objective aligned with the interests of participating NIH Institutes, Centers, and Offices. Applications must include an administrative core, multiple research projects connected by a common scientific focus, and at least one resource core, with an optional pilot projects core. The program emphasizes collaboration and synergy among projects to achieve results that extend beyond individual efforts through shared resources and coordinated impact. This funding opportunity encourages long-term, integrated research efforts that advance the NIH mission by addressing key scientific priorities of the participating ICOs. Awards are authorized under the Public Health Service Act and relevant federal regulations, with the Office of Extramural Activities serving as the point of contact. The grant seeks to foster cohesive, impactful research centers that leverage multidisciplinary expertise to drive significant progress in their thematic area.
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Full Description
Through this Notice of Funding Opportunity (NOFO), the participating NIH Institutes, Centers, and Offices (ICOs) encourage pursuit of the NIH’s mission through the submission of investigator-initiated Specialized Center (P50) applications. With this Parent P50 NOFO, the NIH ICOs intend to support a broadly based, multidisciplinary, often long-term research program with a specific major scientific objective or theme. The proposed Specialized Center must be related to the programmatic interests of one or more of the participating ICOs based on their scientific missions. Applications submitted in response to this NOFO are required to include one administrative core, research projects, and at least one resource core. Inclusion of a Pilot Projects core is optional. The research projects included within the Specialized Center must share a common central scientific theme, focus, and/or an overall objective. Emphasis on how the component research projects build on one another to achieve goals beyond the scope of each individual project is also expected. Specialized Center must demonstrate synergy through cohesiveness, shared resources, and collaborative impact. Statutory authority: Awards are made under the authorization of Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.
