This Event opportunity from Department Of Health And Human Services was posted on March 16, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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One Comprehensive Universal Radiotherapy for Everyone (1-CURE) Proposers' Day

Closed

ARPA-H-SN-26-152Federal

Submission Closed03/23/2026, 12:00:00 PM EDT

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

Active Opportunities Like This One

NAICS: 541715

New

Grant

RFA # 20849 / SFS # ISHRSB1-27

Solicitation # DOH01-ISHRSB1-27-111326900AM

The New York State Department of Health, Wadsworth Center, is offering 620,000 dollars in funding over a one year term to support breast cancer research and education programs. This initiative aims to reinvigorate the scientific community and expand peer reviewed research statewide by providing supplemental funding to community based organizations with existing educational programs. The primary goal is to implement innovative projects focused on general education and breast cancer risk reduction while filling critical gaps in current funding. Interested parties must respond to solicitation number DOH01-ISHRSB1-27-111326900AM by the deadline of January 6, 2027. This state level opportunity is designed to create a continuum of competitive funding for investigator initiated studies and projects. Primary contact for this solicitation is David Googins within the Extramural Grants Administration.

New York State Department of Health

POSTED

DEADLINE

Fire Dynamics & Thermal Modeling ServicesThis subcontract for Fire Dynamics and Thermal Modeling Services supports the Naval Surface Warfare Center Philadelphia Division within the Department of Defense. The selected provider will perform advanced modeling and simulation to analyze fire and blast impacts, specifically focusing on fire dynamics, smoke spread, water mist dynamics, and gaseous fire suppression. A critical component of the scope involves conducting heat transfer modeling for lithium battery thermal runaway and blast impact analysis utilizing PHAST and FLACS tools. The project requires specialized expertise in conjugate heat transfer and thermal runaway sustained peak heat loading to ensure accurate safety and impact assessments. The primary deliverable consists of detailed thermal and blast impact analysis reports provided to prime contractors. Interested parties should note the response deadline of December 14, 2026, under NAICS code 541715.

Nswc Philadelphia Division

POSTED

DEADLINE

Solicitation # DARPA-PS-27-06

The Defense Advanced Research Projects Agency (DARPA) Strategic Technology Office is soliciting proposals for Unison, a program focused on developing collaborative-autonomy approaches that jointly adapt team decision-making and communications during mission execution. The program aims to enable autonomous teams of tens to hundreds of agents to modify tactics, behaviors, and information exchange as mission complexity increases or communications become degraded. This effort is divided into two Technical Areas: Joint Co-adaptation (TA-1) and Modeling and Simulation Environment (TA-2). The core objective is to preserve mission performance while reducing communication dependence and the reasoning burden on individual agents in dynamic, resource-constrained environments. This procurement is conducted via an Other Transaction Agreement (OTA) for Prototypes under 10 U.S.C. 4022. Key requirements include CMMC Level 2 self-assessment and compliance with NIST SP 800-171 Rev 2 and DoD Instruction 5200.48 for the protection of Controlled Unclassified Information (CUI). Awards will be based on technical approach, relevant qualifications in autonomy and communications, budget realism, and the extent of government data rights. Performance is measured through a milestone-based approach with specific exit criteria, including computational tractability and repeatability. Proposals must be submitted as encrypted zip files in LaTeX format to the BAA Coordinator by the specified deadline.

Defense Advanced Research Projects Agcy

POSTED

DEADLINE

DHS SMALL BUSINESS INNOVATION RESEARCH (SBIR) PROGRAM FY27 PRE-SOLICITATION

Solicitation # DHSSBIRFY27PRE

The Department of Homeland Security (DHS) has issued a pre-solicitation for the FY27 Small Business Innovation Research (SBIR) Program, intended for planning purposes to prepare small business concerns for the upcoming 27.1 Solicitation. This program is structured into three phases: Phase I focuses on determining scientific and technical feasibility; Phase II aims to develop a well-defined deliverable prototype; and Phase III focuses on the commercialization of the research into viable products or services. The total contract duration, including options, cannot exceed 36 months, and all research and development must be performed within the United States. To be eligible, offerors must register with SAM.gov, the SBA Company Registration Database, and the DHS SBIR Portal. Entities majority-owned by venture capital firms, hedge funds, or private equity firms are ineligible, and Phase I applicants must meet or exceed the Phase II Transition Rate Benchmark. Proposals will be evaluated based on technical merit, staff qualifications, potential for commercialization, and cost reasonableness. Submissions must be made via the DHS SBIR Portal, adhering to strict formatting requirements, including a single PDF for the technical proposal and a JPEG or PNG for the briefing chart.

Sci Technology Acq Division

POSTED

DEADLINE

Preclinical Medications Discovery and Abuse Liability Testing for NIDA

Solicitation # 75N95022C00004

The National Institute on Drug Abuse, a part of the National Institutes of Health, intends to award a sole source modification to Virginia Commonwealth University under contract number 75N95022C00004. This action will extend the period of performance for the Preclinical Medications Discovery and Abuse Liability Testing program by 12 months, extending the deadline to February 21, 2027. The extension is designed to prevent disruptions in the development of therapeutics for pre-clinical and clinical trials while a new contract is planned and competed. This is a presolicitation notice and not a request for competitive proposals. However, interested parties may submit capability statements and supporting documentation to the contracting officer by November 27, 2026, to demonstrate their ability to fulfill the requirements. The government will use these responses to determine whether to proceed with the non-competitive award or move toward a competitive procurement process.

National Institutes Of Health Olao

POSTED

DEADLINE

Valkryn Testos C2Net Integration and Evaluation platform

Solicitation # FA2823-27-Q-A001

The Air Force Test Center Operational Contracting Division intends to award a sole-source, Firm Fixed Price Commercial Purchase Order to Valkryn Systems, Inc. for the procurement of the Valkryn TestOS C2Net Integration and Evaluation platform. This platform will serve as the baseline for JIATF-401/ATEC Data Mesh c-sUAS testing. The scope of work is divided into three specific contract line item numbers, including two units of TestOS Enclave Hosting and Ingestion, one unit of Real-Time Live Sensor Integration, and two units of Software License and Reachback. The project is categorized under NAICS code 541715 with a size standard of 1,000 employees. The anticipated award date is November 23, 2026, with performance taking place in Florida. This action is a Notice of Intent and not a request for proposals; however, written responses regarding the intent to sole source must be submitted to Jala McLaughlin by 12:00 PM CDT on November 16. The contracting officer for this effort is Gretchen A. Tubolino.

POSTED

DEADLINE

Prototype development for Battlefield Wound Infection Prevention and Treatment (BWI P&T) Barrier Combination

Solicitation # HT9427-26-R-E020

The Defense Health Agency Contracting Activity is seeking proposals for the development of a Battlefield Wound Infection Prevention and Treatment Barrier Combination prototype. This medical countermeasure must integrate a physical wound barrier with antimicrobial and antifungal properties to prevent systemic infections in combat scenarios. The project aims to advance the technology from a preferred starting point of Technology Readiness Level 5 to TRL 8, culminating in a product that has received U.S. Food and Drug Administration approval or clearance. The scope of work includes preclinical testing, human clinical trials, and the submission of regulatory packages such as New Drug Applications or Premarket Approval Applications. This effort is being conducted under prototype Other Transaction Authority 10 U.S.C. 4022, meaning it does not follow standard FAR-based procurement processes. The government prefers a Firm Fixed Price agreement, though Cost Plus Fixed Fee is acceptable. The estimated period of performance is 48 months, divided into prototype demonstration, clinical studies and regulatory submissions, and final FDA review. To be eligible, offerors must be registered in the System for Award Management and demonstrate participation by nontraditional defense contractors or non-profit research institutes, or provide a significant cost share. Proposals are due by November 20, 2026, and will be evaluated based on the proposer's demonstrated ability to successfully develop and deliver the prototype.

Defense Health Agency

POSTED

DEADLINE

GPS Ground Segment Monitor Station Service (MSS)

Solicitation # SSC-GCS-MSS-SSN-2026-2

FA8807 Military Commission And Pnt Ssc/cgk

POSTED

DEADLINE

Cloud-Based Command and Control Plus (CBC2+) Voice Communications Request for Information (RFI)

Solicitation # FA861227RB003

The Department of the Air Force Portfolio Acquisition Executive for Command, Control, Communications and Battle Management is conducting market research for the Cloud-Based Command and Control Plus program. The agency is seeking mature commercial, non-developmental, government-developed, or emerging capabilities designed to integrate and manage voice and radio communications within cloud and edge command-and-control environments. This effort is issued as a Request for Information under solicitation number FA861227RB003 and is intended solely for market research purposes. It does not constitute a formal request for proposal or a commitment to contract for any services. Interested parties must provide their responses by the deadline of December 11, 2026.

FA8612 Aflcmc C3BM C3

POSTED

DEADLINE

Request for Information (RFI) for a Cislunar Space System (CSS)

Solicitation # 10302026-01

The Department of the Air Force is conducting market research via a Request for Information to inform the acquisition strategy for a Cislunar Space System (CSS). The program seeks a rapid, low-risk solution to develop and field up to five space vehicles (SVs) designed to operate throughout cislunar space, including Earth-Moon transfers and libration point orbits. These seed vehicles will support government-provided payloads and serve as a foundation for a potential future proliferated cislunar constellation. The required system must encompass a space segment with compact bus designs, a ground segment for mission management and command and control, a communication segment supporting responsive tasking, and integration with a government-provided National Security Space Launch booster. Key technical objectives include a payload capacity of up to 2,000 kg, a design life of three to five years, and power requirements ranging from a 1 kW threshold to a 3 kW objective. The system must also implement NSA Type-I encryption and decryption for cybersecurity. The notional schedule targets an Authority to Proceed for preliminary design work in the second quarter of FY27, with initial launch capability by late CY29 and operational initial on-orbit capability by CY31. Following the review of industry capabilities and rough order of magnitude cost estimates, the government intends to award up to five Firm Fixed Price preliminary design study contracts.

Department Of The Air Force

POSTED

DEADLINE

Request for Proposal (RFP) - Resilient Missile Warning Tracking (RMWT) Low Earth Orbit (LEO) Ground Entry Points (GEPs)

Solicitation # FA240126R0003

The Space Development Agency is soliciting proposals under solicitation FA240126R0003 for the Resilient Missile Warning Tracking Low Earth Orbit Ground Entry Points effort. This acquisition is structured as an Indefinite Delivery/Indefinite Quantity contract with a ceiling of 369 million dollars. The scope of work encompasses the development, integration, test, operations, and maintenance of Tranche 3 Ground Entry Points at multiple globally dispersed locations. Key requirements include civil engineering for site construction, the procurement and installation of communications shelters, antennas, optical terminals, and networking equipment, as well as the provision of technical services such as site surveys and onsite test support. The contract utilizes a best-value tradeoff source selection process where technical, management, and past performance factors are significantly more important than price. Proposals must be submitted in seven volumes via the DoD Secure Access File Exchange by 4:00 PM Eastern Time on December 18, 2026. The pricing structure includes Firm Fixed Price arrangements for primary labor and materials, with Cost No Fee for other direct costs and travel. The period of performance consists of an ordering period from March 31, 2027, to September 30, 2031, followed by an option period extending to September 30, 2035. Large business offerors are required to meet a minimum small business participation requirement of 5 percent.

FA2401 Space Development Agency Sda

POSTED

DEADLINE

ACC-DTA Commercial Solutions Opening (CSO)

Solicitation # W912CH-26-S-0001

The Army Contracting Command – Detroit Arsenal (ACC-DTA) Commercial Solutions Opening (CSO), solicitation W912CH-26-S-0001, is a rapid-acquisition vehicle designed to transition cutting-edge commercial technologies into active defense programs. Operating through 2028, this CSO utilizes a streamlined, multi-phased competitive process consisting of solution briefs, presentations, and commercial solution proposals. The program supports a diverse customer base, including the Intelligence and Security Command (INSCOM) and six Portfolio Acquisition Executives, focusing on the development, integration, and sustainment of ground vehicle systems to enhance Army modernization and operational readiness. The CSO encompasses various Areas of Interest (AoIs) with diverse technical requirements, such as the FALCONS long-range sensor prototype, C-UAS detection systems, the TIGER Readiness program for Abrams tank engines, and the Light Tactical Trailer Heavy Chassis. Depending on the AoI, the government may award fixed-price contracts under FAR Part 12, non-FAR transaction agreements under 10 U.S.C. 4022, or Cooperative Agreements under 31 U.S.C. 6305. For example, the FALCONS prototype effort features funding ceilings of $24 million to $30 million based on the use of government-provided hardware. Evaluation is based on technical merit, schedule realism, and affordability, with ratings of Acceptable or Unacceptable. Awardees must be registered in the System for Award Management (SAM) and utilize the Wide Area Work Flow (WAWF) for invoicing. Strict compliance is required for the Buy American Act and Specialty Metals clauses, particularly for critical components. All submissions must remain unclassified, and the government reserves the right to modify phases or add new AoIs as requirements evolve.

W6QK Acc- Dta

POSTED

1 day ago

DEADLINE

in about 2 years

General Info

Agency

Department Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

Set-Aside

NONE

Documents

special-notice

High

other

Low

AI Contract Breakdown

Uniform Contract Format

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Timeline

PhaseClosed

PostedMar 16

event

Response DeadlineMar 23

Deadline has passed

Submission Closed

03/23/2026, 12:00:00 PM EDT

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Organization & Contact Information

AgencyDepartment Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)

Contacts1 person available

OfficeWashington, DC, 20005, USA

Organization / AgencyDepartment Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)

Office AddressWashington, DC, 20005, USA

Contacts

The 1-CURE Team

Full Description

This Special Notice (SN) alerts the scientific community to a newly approved ARPA-H program and notifies potential proposers of an associated Proposers’ Day.

See attached 1CURE_SN_ARPA-H-SN-26-152 for further details. A Lightning Talk Template is also provided for convenience.