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Synthetic Biology Research & Development

Active

Federal

Response Deadline08/06/2026, 12:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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The contract aims to advance research and development in synthetic biology to design and engineer microbial biosensors capable of detecting chemical, biological, and radiological threats. The work will focus on the creation of novel genetic circuits, optimization of microbial host systems for enhanced performance, and rigorous validation of biosensor functionality under realistic operational conditions. This effort is intended to produce highly sensitive and specific living sensors that can rapidly identify hazardous agents in complex environments, supporting defense and security applications. The project is classified as a subcontract under the NAICS code 541715 and is managed by the Defense Advanced Research Projects Agency within the Department of Defense. The solicitation was posted on July 30, 2026, with a response deadline of August 6, 2026. While specific performance locations and point of contact details are not provided, the initiative is part of a broader national effort to leverage synthetic biology for next-generation threat detection capabilities, requiring advanced expertise in genetic engineering, microbiology, and systems biology.

General Info

Develop synthetic biology biosensors for detecting chemical, biological, and radiological threats under DARPA support.

Agency

Department Of Defense → Defense Advanced Research Projects AgcyView Agency

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)View NAICS

Place of Performance

VA

Set-Aside

NONE

Documents

(0)

No documents available

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Timeline

PostedJul 30

subcontract

Response DeadlineAug 6

Submission deadline

Response Deadline

08/06/2026, 12:00:00 PM UTCin 6 days

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Organization & Contact Information

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AgencyDepartment Of Defense → Defense Advanced Research Projects Agcy

ContactsNo contacts available

OfficeN/A

Organization / Agency

Department Of Defense → Defense Advanced Research Projects Agcy

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Office AddressN/A

ContactsNo contact information available

Full Description

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Conduct R&D in synthetic biology to engineer microbial biosensors for detecting chemical, biological, and radiological threats. Includes genetic circuit design, host optimization, and biosensor validation.

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POSTED

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Sensor System Integration & PackagingThe contract seeks the integration of focal plane arrays, return on investment calculations, and thermal cooling systems into ruggedized, field-deployable sensor modules designed for operation across terrestrial, maritime, air, and space environments. These modules must withstand extreme conditions while maintaining high-performance thermal and electro-optical functionality, ensuring reliability in demanding operational scenarios. The work emphasizes compact packaging, durability, and seamless system-level integration to support deployment on diverse mobile and remote platforms without compromising sensor fidelity or operational readiness. This subcontract falls under NAICS code 334511 for electromedical and electrotherapeutic equipment manufacturing, though the scope clearly targets advanced sensor system development rather than medical applications. The opportunity is posted by the Defense Advanced Research Projects Agency under the Department of Defense with a response deadline of August 14, 2026. No set-aside provisions or specific eligibility criteria are indicated, and performance is expected to occur on a national scale without a defined geographic restriction. The contract requires proven expertise in packaging sensitive electro-optical components for harsh environments and the ability to deliver integrated systems that meet rigorous military and aerospace standards for size, weight, power, and thermal management.

Search, Detection, Navigation, Guidance, Aeronautical, and Nautical System and Instrument Manufacturing

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DEADLINE

Cryogenic Cooling System IntegrationThe contract seeks the development and integration of compact, low-power cryocoolers designed specifically for use with cooled infrared detectors, with a focus on Stirling and pulse-tube cooling technologies. The goal is to advance thermal management systems that enable high-performance infrared sensing in space-constrained and power-limited environments, typically critical for defense and aerospace applications. The work must deliver systems that are not only efficient and reliable but also engineered for seamless integration into existing or next-generation sensor platforms. This is a subcontract opportunity issued under the Department of Defense through the Defense Advanced Research Projects Agency, with a North American Industry Classification System code of 333415, indicating it falls within the area of refrigeration and air conditioning equipment manufacturing. The solicitation was posted on July 17, 2026, and responses are due by August 14, 2026. The place of performance and specific agency office details are not provided, but performance is expected to support national defense objectives, likely requiring compliance with federal procurement standards and technical specifications for ruggedized, field-deployable cryogenic systems.

Air-Conditioning and Warm Air Heating Equipment and Commercial and Industrial Refrigeration Equipment Manufacturing

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DEADLINE