This Government Contract opportunity from Department Of Health And Human Services was posted on May 19, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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TCR Construct Optimization and Genetic Engineering

Closed

Federal

Submission Closed06/03/2026, 01:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541715

New

Federal

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Marshall Space Flight Center

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Engineering and Technical Support Services for Flight Research and Development (ETSS)The contract involves providing comprehensive engineering and technical support services for flight research and development at NASA's Armstrong Flight Research Center, located in Edwards. The scope covers a wide range of specialized disciplines including research, flight operations, aerodynamics, propulsion, dynamics and controls, advanced systems development, flight instrumentation, systems integration, aerostructures research, and range and subscale flight research. Additionally, support for safety and mission assurance is a critical component of the work, ensuring the reliability and security of flight research missions. The contractor is expected to supply all necessary personnel, services, and materials to support flight research projects, internal research and development efforts, and various technical functions. This includes providing disciplinary engineering expertise across multiple research and technical domains to support NASA’s ongoing innovation and operational goals in aerospace engineering. The work is forecasted to be under the NAICS code 541715, with key agency contacts identified to facilitate communication and coordination.

Armstrong Flight Research Center

POSTED

in 7 months

DEADLINE

N/A

AI Contract Overview

This contract involves the design and optimization of the A11 HERV-E T-cell receptor construct, aiming to improve its antigen specificity, binding affinity, and T-cell activation capabilities. The work includes genetic engineering tasks such as codon optimization and vector design, alongside comprehensive in vitro validation to ensure the enhanced functionality of the T-cell receptor. The project is focused on advancing the efficacy of this receptor construct for potential therapeutic applications. The subcontract is issued by the National Institutes of Health under the Department of Health and Human Services, with the place of performance located in Bethesda. The contract falls under the NAICS code 541715, which pertains to research and development in the physical, engineering, and life sciences. Proposals for this work were to be submitted by June 3, 2026, following the solicitation posted on May 19, 2026.

General Info

Design and optimize A11 HERV-E T-cell receptor for improved specificity and activation, with in vitro validation.

Agency

Department Of Health And Human Services → National Institutes Of Health Olao

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) View NAICS

Place of Performance

Bethesda, MD, 20892, USA

Set-Aside

NONE

Documents

(0)

No documents available

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Timeline

PhaseClosed

PostedMay 19

subcontract

Response DeadlineJun 3

Deadline has passed

Submission Closed

06/03/2026, 01:00:00 PM UTC

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Organization & Contact Information

AgencyDepartment Of Health And Human Services → National Institutes Of Health Olao

ContactsNo contacts available

OfficeN/A

Organization / Agency

Department Of Health And Human Services → National Institutes Of Health Olao

Office AddressN/A

ContactsNo contact information available

Full Description

Design and optimization of the A11 HERV-E T-cell receptor construct to enhance antigen specificity, binding affinity, and T-cell activation, including codon optimization, vector design, and in vitro validation.