This Pre-Solicitation opportunity from Department Of Health And Human Services was posted on August 15, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Title: Cellink BIO X Advanced Multi-Material 3D Bioprinting System for Cancer Biology and Organoid Research

Closed

75N98026Q01018CELLINKNCI09639Federal

Submission Closed08/15/2026, 01:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541714

New

Grant

Genomic Data Generation Center for the Gabriella Miller Kids First Pediatric Research Program (U24 Clinical Trial Not Allowed)

Solicitation # RFA-RM-27-008

The National Institutes of Health, under the Department of Health and Human Services, is seeking applications for Genomic Data Generation Center(s) to support the Gabriella Miller Kids First Pediatric Research Program. The primary objective is the rapid production of high-quality sequence and variant data from human specimens related to pediatric conditions, specifically childhood cancers and congenital anomalies. Required data types include genome-wide, RNA, and long-read DNA and RNA sequencing, as well as chromatin accessibility data and genome-wide methylation profiling. All generated data will be re-processed and harmonized by the Kids First Pediatric Data Resource Center to maintain a public-facing, cloud-based resource for the research community. The NIH Common Fund intends to commit 5 to 6 million dollars annually for a maximum award period of three years, with an award ceiling of 3.5 million dollars. Applications are due by January 8, 2027, and will be evaluated via the NIH peer review system based on significance, investigator qualifications, innovation, and approach. A key requirement is the center's agility to implement new assays within a two-month timeframe. This opportunity is restricted to projects that do not propose clinical trials. Eligible applicants must maintain active registrations in SAM, eRA Commons, and Grants.gov. Awardees must adhere to strict cybersecurity protocols, including multifactor authentication and a 48-hour incident notification window, and comply with federal regulations 42 CFR Part 52 and 2 CFR Part 200. Proposals must include itemized per-sample costs, a minimum sample estimate, and a plan for cost reduction over the award period. All research involving human subjects must comply with 45 CFR Part 46, and a comprehensive Data Management and Sharing Plan is required at the time of application.

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Senior Advisor for Neurotherapeutic Network (Small Molecules)The Senior Advisor for Neurotherapeutic Network (Small Molecules) is a small business set-aside subcontract through the Department of Health and Human Services Omas Strategic Buying Center. The selected consultant will provide executive-level subject matter expertise to prime contractors supporting NIH NINDS Blueprint Neurotherapeutic Network projects. Primary responsibilities include reviewing program operations, offering strategic recommendations for pharmacology-related trials, and leading drug discovery teams focused on small molecules for nervous system conditions. Qualified candidates must possess a PhD in Pharmacology, an MD, or an advanced degree in Organic Chemistry. The role requires the delivery of high-level technical reports, detailed scientific analyses, and formal recommendations to meet project milestones. This opportunity was posted on October 28, 2026, with a response deadline of November 5, 2026, falling under NAICS code 541714.

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High-throughput Unmasking of Biological Interactomes with Binding Landscape Emulators (HUBBLE)

Solicitation # DARPA-PA-27-01

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Defense Advanced Research Projects Agcy

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Pharmacology and Pain Drug Development SMEThis subcontract opportunity through the Department of Health and Human Services Omas Strategic Buying Center seeks a subject matter expert in pharmacology and pain to support prime contractors on NIH HEAL Initiative projects. The selected expert will provide executive-level guidance on small molecule and biologic therapeutics, focusing on drug discovery and pharmacology-related trials for nervous system conditions. Key responsibilities include performing strategic programmatic reviews, evaluating milestones, and providing mentorship. The role requires the delivery of strategic recommendations and milestone evaluations through formal committee reports. Performance will take place in Bethesda, and the opportunity is categorized under NAICS code 541714. Interested parties should note the response deadline of November 3, 2026.

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Precision Prevention & Biological Pathway ResearchThe Precision Prevention and Biological Pathway Research subcontract supports prime contractors on Defense Health Agency Alzheimer’s Research Program projects. The primary objective is to conduct research linking service-related exposures to AD/ADRD biological pathways by quantifying military-relevant risk factors. This technical work involves the use of proteomics tools and genomic sequencing to map these biological pathways, culminating in the delivery of detailed research reports and data. Performance of this contract takes place in Frederick, Maryland, under NAICS code 541714. Due to the nature of the study, the contractor must obtain IRB approval and maintain all necessary Human Subjects Research certifications. Interested parties should note the response deadline of December 4, 2026.

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Blood-Based Biomarker Validation & ScalingThis subcontract focuses on the validation and scaling of blood-based biomarkers to support prime contractors within the Defense Health Agency Alzheimer’s Research Program. The scope of work involves performing detailed laboratory analysis of blood samples, validating the sensitivity and specificity of assays, and establishing scalable testing protocols. These operations must utilize Simoa equipment and biobanking systems while adhering strictly to GLP standards and maintaining CLIA certification. The project is managed under the Department of Defense and is centered in Frederick, Maryland. The primary objective is the delivery of validated, scalable biomarker assays and protocols to advance research goals. Interested parties should note the response deadline of December 4, 2026, and the classification of the work under NAICS code 541714.

Defense Health Agency

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DEADLINE

RFI Alzheimer’s Research Program (AZRP) Public

Solicitation # HT9427RFI2027AZRP

The Defense Health Agency, through the Congressionally Directed Medical Research Programs, has issued a Request for Information under solicitation number HT9427RFI2027AZRP to gather strategic feedback for the fiscal year 2027 Alzheimer’s Research Program. The primary objective is to identify research focus areas and funding opportunities aimed at mitigating the impact of Alzheimer's and related dementias, specifically those associated with traumatic brain injury, military service, and diverse risks. The program seeks to improve the quality of life for Service Members, Veterans, and their families by funding solution-oriented research, including the development of digital and blood-based biomarkers for early diagnosis and the creation of precision prevention strategies. This action is strictly for information and planning purposes and does not constitute a formal solicitation, request for proposals, or request for quotations. No contracts will be awarded based on this announcement, and FY27 funds have not yet been appropriated. Interested parties from academia, industry, non-profit organizations, and federal agencies are invited to provide feedback via Survey Monkey by December 4, 2026. Respondents are cautioned not to submit proprietary or sensitive information through the survey portal as it cannot be protected. The effort is categorized under NAICS code 541714 and is managed by the Department of Defense in Fort Detrick, Maryland.

Defense Health Agency

POSTED

DEADLINE

Traumatic Brain Injury and Psychological Health Research Program Public Request for Information

Solicitation # HT9427RFI2027TBIPHRP

The Defense Health Agency, under the Department of Defense and the Congressionally Directed Medical Research Programs, has issued a Request for Information under solicitation number HT9427RFI2027TBIPHRP. This action is strictly for strategic planning and is not a formal solicitation, request for proposals, or request for quotations. The primary objective is to gather feedback from academia, industry, non-profit organizations, and the public to inform the research focus areas and funding opportunities for the fiscal year 2027 Traumatic Brain Injury and Psychological Health Research Program. The program aims to optimize the prevention, assessment, and treatment of psychological health conditions and traumatic brain injuries to benefit Service Members, Veterans, and the general public. Interested parties are asked to provide input on research gaps and funding priorities, specifically regarding the prevention, screening, diagnosis, and treatment of these conditions. Responses must be submitted via Survey Monkey by December 11, 2026. Because the government cannot protect proprietary or sensitive information submitted through the survey platform, such data should not be included. This inquiry does not commit the program to incorporating the feedback into future funding opportunities, and no contract will be awarded based on this specific announcement. All inquiries regarding this RFI should be directed to Patrick M. Younkins.

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DEADLINE

Request for Proposals (RFP) - BARDA Vaccine Medical Countermeasures for Pandemic Influenza Preparedness & Response

Solicitation # 75A50126R00001_RFP_NPIVS_27

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Barda - Aspr / Daappo / Barda Dcma

POSTED

DEADLINE

USDA SBIR/STTR Topic 8.2 — Plant Production and Protection - Biology

Solicitation # USDA-NIFA-TOPIC-8.2

The USDA National Institute of Food and Agriculture is soliciting proposals under Topic 8.2 for Plant Production and Protection - Biology. This initiative focuses on advancing crop production and protection through the development of innovative plant breeding methods, diagnostic technologies for diseases, and the creation of new food and non-food crop plants. Research efforts are directed toward improving plant characteristics to mitigate biotic and abiotic stresses, developing new genotypes for commercial applications, and creating tools to support the health of natural and domesticated pollinators. This opportunity is a total small business set-aside under the SBIR/STTR mandate, restricting eligibility to companies with fewer than 500 employees. Managed by the United States Department of Agriculture, the program is led by Dr. Christopher Philips. Interested parties can find further details and application guidelines through the NIFA website.

National Institute of Food and Agriculture

POSTED

DEADLINE

Quantitative Analysis of Longitudinal MR Images

Solicitation # 75N98027R00005

Solicitation 75N98027R00005 is a Sources Sought notice issued by the National Institute on Aging (NIA) to identify qualified companies capable of performing quantitative analysis of longitudinal Magnetic Resonance (MR) images. The project supports the Baltimore Longitudinal Study of Aging (BLSA) by processing 300 newly acquired MR datasets to characterize brain aging trajectories and identify predictors of cognitive decline and Alzheimer’s disease. The selected contractor will provide specialized, non-commercial services to deliver global and regional tissue volumes, lesion quantification, and machine learning-derived scores, such as SPARE-AD, while ensuring longitudinal consistency with data acquired since 1994. The anticipated contract will be a firm fixed price award with a period of performance of one year. Key deliverables include quantitative volumetric results, intermediate processing files, and registration maps for PET overlay, submitted every six months, concluding with a final report. Technical requirements emphasize the use of established image analysis tools and adherence to FISMA/FedRAMP-aligned data security controls to protect participant confidentiality. Interested respondents must submit a capability statement by November 9, 2026, to Contract Specialist Sneha Singh. The submission must be limited to ten pages and include the company's Unique Entity ID, NAICS code 541714, professional qualifications of personnel, and any applicable GSA schedules or government-wide acquisition contracts. Small businesses are encouraged to respond to this market research effort to help the government determine the appropriate acquisition method.

National Institutes Of Health Olao

POSTED

7 days ago

DEADLINE

in 10 days

AI Contract Overview

The National Institutes of Health is seeking a Cellink BIO X Advanced Multi-Material 3D Bioprinting System to support cancer biology and organoid research within the Muthuswamy Laboratory. This high-precision platform is required to replace manual preparation techniques that currently cause variability in tissue geometry and cell distribution, thereby improving experimental reproducibility and the complexity of 3D tissue models. The system will be used to investigate tumor initiation, progression, and therapeutic responses by fabricating multicellular constructs that simulate interactions between tumor cells and their surrounding environments. The procurement, identified by solicitation number 75N98026Q01018CELLINKNCI09639, is a presolicitation under NAICS code 541714. The equipment must integrate with existing microscopy, cell culture, and molecular analysis workflows at the performance site in Bethesda, Maryland. The primary point of contact for this requirement is Vishnuvajjala Hanumanth Rao.

General Info

NIH seeks a Cellink BIO X 3D Bioprinting System for cancer organoid research.

Agency

Department Of Health And Human Services → National Institutes Of Health Olao

NAICS

541714 - Research and Development in Biotechnology (except Nanobiotechnology)

Place of Performance

Bethesda, MD, 20892, USA

Set-Aside

NONE

Documents

Notice of Intent - CELLINK

3 pages · presolicitation

Low

AI Contract Breakdown

Uniform Contract Format

Timeline

PhaseClosed

PostedAug 15

Presolicitation

Response DeadlineAug 15

Deadline has passed

Submission Closed

08/15/2026, 01:00:00 PM UTC

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Organization & Contact Information

AgencyDepartment Of Health And Human Services → National Institutes Of Health Olao

Contacts1 person available

OfficeBETHESDA, MD, 20892, USA

Organization / AgencyDepartment Of Health And Human Services → National Institutes Of Health Olao

Office AddressBETHESDA, MD, 20892, USA

Contacts

Vishnuvajjala Hanumanth Rao

contact@example.gov

Full Description

THE LABORATORY INVESTIGATES MECHANISMS FO TUMORS INITIATIONS PROGRESSION AND THERAPEUTIC RESPONSE USING ADVANCED THREE DIMENSIONAL(3d) CULTURE SYSTEMS ORGANID MODELS AND ENGINEERED TISSUE MICRONMENTS . CURRENT RESEARCH FOCUESES ON UNDERSTANDING INTERACTIONS BETWEEN TUMORS CELLS AND THERI SURROUNDING STROMAL AND EXTRACULLULAR MATRIX ENVIRONMENTS THAT INFLUENCE CANCER DEVELOPMENT AND TREATMENT RESPONSE. EXISTING LABORATORY METHODS FOR GENERATING 3D TISSUEMODELS RELYON MANUAL PREPRATION TECHNIQUES THAT INTRODUCE VARIABILITY IN CONSTRUCT GEOMETRY, CELL DISTRUBUTION, AND EXTRACELLULAR MATRIX COMPOSITION. THESE LIMITATIONS REDUCE EXPERIMENTAL REPRODUCIBILITY AND RESTRICT THE COMPLEXITY OF TISSUE MODELS THAT CAN BE GENERATED. TO SUPPORT ONGOING NIH-FUNDED RESEARCH, THEMUTHUSWAMY LABORATORY REQUIRES A HIGH-PRECISION 3DE BIOPRINTING PLATFORM CAPABLE OF REPRODUCIBLY FABRICATING MULTICELLULAR TISSUE CONSTRUCTS USING A VARIETY OF BIOMARKS AND BIOMATERIALS. THE SYSTEM MUST INTEGRATE WITH EXISTING CELL CULTURE, MICROSCOPY, AND DOWNSTREAM MOLECULAR ANALYSIS WORKFLOWS WHILE ENABLING STANDARDIZED PRODUCTION OF PHYSIOLOGICALLY RELEVENT INVITRO MODELS.