This Pre-Solicitation opportunity from Department Of Health And Human Services was posted on August 15, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.
Title: Cellink BIO X Advanced Multi-Material 3D Bioprinting System for Cancer Biology and Organoid Research
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The National Institutes of Health is seeking a Cellink BIO X Advanced Multi-Material 3D Bioprinting System to support cancer biology and organoid research within the Muthuswamy Laboratory. This high-precision platform is required to replace manual preparation techniques that currently cause variability in tissue geometry and cell distribution, thereby improving experimental reproducibility and the complexity of 3D tissue models. The system will be used to investigate tumor initiation, progression, and therapeutic responses by fabricating multicellular constructs that simulate interactions between tumor cells and their surrounding environments. The procurement, identified by solicitation number 75N98026Q01018CELLINKNCI09639, is a presolicitation under NAICS code 541714. The equipment must integrate with existing microscopy, cell culture, and molecular analysis workflows at the performance site in Bethesda, Maryland. The primary point of contact for this requirement is Vishnuvajjala Hanumanth Rao.
General Info
Agency
NAICS
Place of Performance
Bethesda, MD, 20892, USASet-Aside
Timeline
Submission Closed
Organization & Contact Information
Full Description
THE LABORATORY INVESTIGATES MECHANISMS FO TUMORS INITIATIONS PROGRESSION AND THERAPEUTIC RESPONSE USING ADVANCED THREE DIMENSIONAL(3d) CULTURE SYSTEMS ORGANID MODELS AND ENGINEERED TISSUE MICRONMENTS . CURRENT RESEARCH FOCUESES ON UNDERSTANDING INTERACTIONS BETWEEN TUMORS CELLS AND THERI SURROUNDING STROMAL AND EXTRACULLULAR MATRIX ENVIRONMENTS THAT INFLUENCE CANCER DEVELOPMENT AND TREATMENT RESPONSE. EXISTING LABORATORY METHODS FOR GENERATING 3D TISSUEMODELS RELYON MANUAL PREPRATION TECHNIQUES THAT INTRODUCE VARIABILITY IN CONSTRUCT GEOMETRY, CELL DISTRUBUTION, AND EXTRACELLULAR MATRIX COMPOSITION. THESE LIMITATIONS REDUCE EXPERIMENTAL REPRODUCIBILITY AND RESTRICT THE COMPLEXITY OF TISSUE MODELS THAT CAN BE GENERATED. TO SUPPORT ONGOING NIH-FUNDED RESEARCH, THEMUTHUSWAMY LABORATORY REQUIRES A HIGH-PRECISION 3DE BIOPRINTING PLATFORM CAPABLE OF REPRODUCIBLY FABRICATING MULTICELLULAR TISSUE CONSTRUCTS USING A VARIETY OF BIOMARKS AND BIOMATERIALS. THE SYSTEM MUST INTEGRATE WITH EXISTING CELL CULTURE, MICROSCOPY, AND DOWNSTREAM MOLECULAR ANALYSIS WORKFLOWS WHILE ENABLING STANDARDIZED PRODUCTION OF PHYSIOLOGICALLY RELEVENT INVITRO MODELS.
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