A -- GM and KM Allotype Analysis

The Centers for Disease Control and Prevention intends to issue a sole source purchase order to Medical University of South Carolina, Charleston, S.C. for a GM and KM Allotype Analysis Contract. CDC's study, Investigation of immunoglobulin (Ig) GM and KM gene polymorphisms in susceptibility to and pathogenesis of malaria and HIV in children and pregnant women in Kenya, involves Ig GM/KM allotype tests in 3,000 samples collected from two concluded malaria and HIV epidemiological projects conducted in Kenya. Professor of Immunology at the Medical University of South Carolina, is an expert on Ig GM/KM allotyping, having investigated these gene polymorphisms as they relate to several infectious diseases including hepatitis C, influenza, typhoid fever, leprosy, onchocerciasis, filariasis and malaria. Professor of Immunology has characterized the genetic allotypes of many different populations including Amazonian tribes, Malaysians, Philippinos, Indian Punjabis, African tribes, Norwegians, Ecuadorian Cayapas, and Chileans. To our knowledge, this is the only laboratory in the United States that has established and standardized those methods for Ig GM/KM allotyping. Professor at the Immunology has authored and co-authored more than 150 papers, 30 book chapters/reviews related to Ig GM/KM allotyping in various infectious diseases over the past 30 years. Professor at the Immunology has recently initiated collaborations with other institutes on the study of Ig GM/KM allotypes in malaria . Collaboration between CDC and MUSC will certainly have substantial impact on Ig GM/KM gentetics in malaria as well as HIV. Results from the initial collaborative study between CDC and MUSC will also be important when applying for NIH collaborative grants in the future to identify and understand the host genetic risk factors in malaria and HIV infection and disease. CDC believes that this requirement is met by only one provider. This procurement will be processed under the authority of FAR 6.302-1 and 6.302-2. Only one responsible source and no other sources will satisfy agency requirements. No solicitation is being issued. However, information received will be considered solely for information purposes only. This procurement is not set-aside for small business. For contractual questions contact Beth West at contact@example.gov.