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This Government Contract opportunity from Department Of Defense was posted on April 10, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

AI/ML in Biological Systems Development

Closed
Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

Active Opportunities Like This One

NAICS: 541715
New
Federal
Atomically Precise Molecules (APM)
Solicitation # DARPA-PS-26-141
The Atomically Precise Molecules (APM) program, solicitation DARPA-PS-26-141, is a 36-month initiative by the DARPA Multi X Office seeking innovative synthesis techniques for programmable precision polymers (PPPs) and nonlinear optical (NLO) materials. The program aims to develop scalable materials with strictly controlled monomer sequences and compositions, culminating in a prototype NLO material integrated into a government-provided electro-optic modulator capable of achieving greater than 1THz modulation. The effort is structured in two phases, with Phase I lasting 12 months and focusing on synthesis capabilities. Research limited to inorganic materials or incremental improvements to existing state-of-the-art practices is specifically excluded. Awards will be issued as Other Transaction for Prototype Agreements, with payments processed through the Wide Area Workflow system based on a schedule of milestones. Proposals are due by December 18, 2026, via the Broad Agency Announcement Tool and must include technical, management, and pricing volumes. Eligibility is restricted to U.S. organizations, and all performers must comply with CMMC Level 2 self-certification and NIST SP 800-171 standards for safeguarding Controlled Unclassified Information. Evaluation will be based on technical approach, relevance to the DARPA mission, budget realism, and the capability to transition the technology to military or commercial sectors.
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DEADLINE

in about 2 months
NAICS: 541715
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Solicitation # FA240126R0003
The Space Development Agency is soliciting proposals under solicitation FA240126R0003 for the Resilient Missile Warning Tracking Low Earth Orbit Ground Entry Points effort. This acquisition is structured as an Indefinite Delivery Indefinite Quantity contract with a ceiling of 369 million dollars, covering the development, integration, test, operations, and maintenance of Tranche 3 Ground Entry Points at multiple globally dispersed locations. The scope of work encompasses civil engineering from detailed design through construction, the procurement and installation of communications shelters, antennas, optical terminals, and networking equipment, as well as the development of Ground Support Equipment and Auxiliary Development Units. The contract includes an ordering period from March 31, 2027, to September 30, 2031, with option periods extending through September 30, 2035. Award will be determined using a best value tradeoff process where technical, management, and past performance factors are combined and considered significantly more important than price. The technical evaluation focuses on the understanding of requirements, feasibility of approach, and scalability, while management is assessed based on project and schedule management, subcontractor oversight, and security handling. Proposals must be submitted in seven volumes via the DoD Secure Access File Exchange by 4:00 PM Eastern Time on November 23, 2026. Large business primes are required to meet a minimum quantitative requirement of 5 percent small business participation. The contract utilizes a mix of Firm Fixed Price for primary labor and materials and Cost Reimbursable arrangements for other direct costs and travel.
FA2401 Space Development Agency Sda

POSTED

about 15 hours ago

DEADLINE

in 27 days
NAICS: 541715
New
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Pioneering Aerospace Capabilities, Engineering and Research
Solicitation # FA2391-23-S-2403
The Pioneering Aerospace Capabilities, Engineering and Research (PACER) program, under solicitation FA2391-23-S-2403, is a comprehensive Broad Agency Announcement issued by the Air Force Research Laboratory (AFRL) Aerospace Systems Directorate. This open, two-step solicitation is designed to fund research and development efforts that mature novel aerospace concepts and technologies to appropriate technology readiness levels, specifically targeting transformative capabilities for the warfighter. The program encompasses a wide array of specialized calls, including efforts for hypersonic weapon concepts (HAMWC), automated air-to-air refueling (CRONUS), advanced propulsion and power systems (SNAPP, AEPO, MSIPPT, HITEMP, INNATE), and multidisciplinary design and structures (MASTR, VOLARE, CC DROIDS). The acquisition process typically involves an initial white paper submission followed by full proposals from selected offerors, though some calls utilize a one-step process. Awards may take the form of contracts or assistance instruments, with anticipated types including Cost Plus Fixed Fee (CPFF), Firm-Fixed-Price (FFP), and IDIQ task orders. Due to the sensitive nature of the research, strict security protocols are enforced, requiring offerors to comply with AFRLI 61-113 for Science and Technology Protection and meet CMMC Level 2 and NIST SP 800-171 standards to access Controlled Unclassified Information (CUI). Proposals are evaluated based on the uniqueness and innovation of the approach, understanding of scope, technical soundness, and transition potential, with cost realism serving as a secondary substantial factor.
FA2391 USAF Afmc Afrl Pzl Afrl Rqkp

POSTED

about 15 hours ago

DEADLINE

in over 4 years

AI Contract Overview

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This subcontract opportunity involves the development of artificial intelligence and machine learning tools focused on analyzing biological data, modeling human performance, and supporting advancements in synthetic biology. The work is intended to enable innovative approaches to understanding complex biological systems and improving performance metrics through AI-driven methodologies. The contract is issued by the Defense Advanced Research Projects Agency under the Department of Defense, highlighting its strategic importance in defense-related biological research. The solicitation does not specify a solicitation number or set-aside status but falls under NAICS code 541715, which pertains to research and development in the physical, engineering, and life sciences. Interested parties must submit their responses by the deadline of May 28, 2026. Although details such as location of performance and points of contact are not provided, the opportunity is accessible via the official government contracting portal for further information.

General Info

Development of AI/ML tools for biological data analysis and synthetic biology, DARPA contract, deadline May 28, 2026.

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

VA

Set-Aside

NONE

Documents

This scope was carved out of DARPA-SN-26-04.

The full solicitation package (2 documents), including the RFP, is on the prime solicitation, not on this scope.

View the prime solicitation

BTO Innovation Opportunity (BIO) Fair

AI Contract Breakdown

Uniform Contract Format

No documents to break down

The breakdown needs solicitation documents. None were found from this contract's source.

Timeline

PhaseClosed
Posted

subcontract

Response Deadline

Deadline has passed

Submission Closed

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Organization & Contact Information

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AgencyDepartment Of Defense → Defense Advanced Research Projects Agcy
ContactsNo contacts available
OfficeN/A
Office AddressN/A
ContactsNo contact information available

Full Description

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Development of AI and machine learning tools for analyzing biological data, modeling human performance, and advancing synthetic biology applications.

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Solid-State Energy Conversion from Heat to Electricity Request for Information (RFI)
Solicitation # DARPA-SS-27-01
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DEADLINE

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Solicitation # DARPA-SN-27-03
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Young Faculty Award (YFA) 2027
Solicitation # DARPARA2701
The Young Faculty Award (YFA) 2027, solicitation DARPARA2701, is a competitive funding opportunity managed by the DARPA Defense Sciences Office. The program is designed to engage early-career researchers at U.S. academic or non-profit research institutions to develop innovative, unclassified basic research that enables transformative national security capabilities for the Department of War. Eligible Principal Investigators must be in a tenure-track position, have achieved tenure within the last three years, or be within twelve years of receiving their doctorate. To ensure the program reaches rising stars, PIs are ineligible if they have previously received more than 500,000 dollars from DARPA or 1.25 million dollars from all Department of War sources combined. Funding is structured around a 24-month base period with a maximum of 500,000 dollars, with a total potential award value of up to 1.225 million dollars including option periods. These options include a 12-month Director's Fellowship and a U.S. Citizen Graduate Student option of up to 225,000 dollars. Proposals are evaluated primarily on overall scientific and technical merit, focusing on innovation, feasibility, risk management, and the expertise of the technical team. Submissions must follow a strict multi-volume format, including a mandatory one-page executive summary due November 5, 2026, and full proposals due January 13, 2027. All personnel must be employed at U.S. institutions, and awardees must comply with federal regulations regarding organizational conflicts of interest and electronic invoicing via Wide Area Work Flow or the Automated Standard Application for Payments system.
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DEADLINE

in 3 months
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