DoW Bone Marrow Failure, Resource Development Award

The fiscal year 2026 Bone Marrow Failure Research Program Resource Development Award seeks to fund the creation of a comprehensive, open-access multioomic atlas derived from well-annotated human bone marrow failure samples, aiming to accelerate scientific and clinical understanding of these diseases. The initiative requires applicants to generate high-quality genomic, transcriptomic, proteomic, and clinical data integrated into a durable, universally accessible resource, with strict adherence to standardized metadata, data quality control, and robust data security practices. A central requirement is the submission of a detailed Data Resource Sharing Plan and a Sustainment Plan, ensuring the atlas remains available and operational beyond the award period through long-term maintenance strategies and archival in approved biomedical repositories. Applications must also include a Project Narrative, Statement of Work, Technical and Lay Abstracts, Data Management Plan, Impact Statement, and additional supporting documents, all formatted as individual PDFs with precise naming conventions and page limits, with the full application limited to a 12-page narrative, a 5-page SOW, and a 2-page sustainment plan among others. The award has a fixed funding cap of $1,250,000 with a maximum project duration of two years, and all submissions must be made through Grants.gov for extramural applicants or eBRAP for intramural Department of Defense entities, with the full application deadline set for November 4, 2026. Evaluation is based on a two-tier review system combining peer assessment of scientific merit with programmatic review of strategic alignment, emphasizing innovation, team expertise, multidisciplinary collaboration, and the potential for transformative impact on bone marrow failure research. While no formal FAR/DFARS clauses apply, compliance with DoD Instruction 3200.12, CDMRP data sharing directives, and regulatory approvals such as IRB/IACUC is mandatory. The award decision follows a trade-off process, enabling selection based on a balanced consideration of technical excellence, portfolio diversity, and sustainability potential rather than technical score alone. Applicants must maintain an active UEI in SAM.gov, include required representations, and ensure all personnel provide biographical sketches and current/pending support documentation, all of which must comply with federal research integrity and inclusion policies. No physical deliveries or FOB terms are involved; the entire performance scope centers on digital data generation, curation, and dissemination.