HIV/AIDS Clinical Trials Network Leadership and Operations Centers
Contract Overview
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AI Contract Overview
The National Institute of Allergy and Infectious Diseases (NIAID) is seeking applications to support four Clinical Trials Networks (CTNs) through Leadership and Operations Centers (LOCs). Each LOC will provide scientific leadership, set research priorities, and conduct studies within specialized focus areas related to HIV, including therapeutics and cure strategies, prevention and treatment of HIV-associated comorbidities in adults, maternal/adolescent/pediatric HIV prevention and treatment, biomedical prevention strategies for adults and adolescents, and immune-based prevention approaches. The CTNs are designed to advance prevention, treatment, and implementation research aimed at ending the HIV epidemic by improving the uptake of evidence-based strategies across diverse populations. This funding opportunity underlines the importance of high-impact LOC studies that generate critical findings to benefit Americans living with or at risk for HIV and related diseases. The contract is authorized under Sections 301 and 405 of the Public Health Service Act and adheres to federal regulations governing health research grants. NIAID’s initiative aligns with the broader NIH mission to foster innovative HIV implementation research that translates into measurable public health improvements. The Division of AIDS within NIAID serves as the point of contact for applicants interested in participating in this collaborative effort.
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Full Description
The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance the National Institutes of Health (NIH) mission by supporting four Clinical Trials Networks (CTNs) each comprised of a Leadership and Operations Center (LOC), Statistical and Data Management Center, and Laboratory Center working with Clinical Trials Units to advance prevention, treatment, and implementation research designed to end the HIV epidemic. This NOFO will solicit applications for four LOCs to provide scientific leadership, research prioritization, and conduct studies in a CTN. A LOC develops the research agenda in one of these areas: 1) HIV therapeutics/cure, and prevention/treatment for HIV-associated comorbidities in adults; 2) HIV prevention/treatment in maternal/adolescent/pediatric populations; 3) biomedical HIV prevention strategies for adults/adolescents; and 4) immune-based prevention for HIV and HIV-associated diseases. CTNs will conduct HIV implementation research improving uptake of evidence-based prevention and treatment strategies across the lifespan. High impact LOC studies will produce crucial findings significantly benefiting Americans with or at-risk of HIV and HIV-associated diseases.
Grant authorities that allow NIAID to forecast this opportunity are: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.
