HIV/AIDS Clinical Trials Network Leadership and Operations Centers
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The National Institute of Allergy and Infectious Diseases, under the Department of Health and Human Services, is forecasting opportunities for four Leadership and Operations Centers to support Clinical Trials Networks aimed at ending the HIV epidemic. These centers will provide scientific leadership and research prioritization across four specific areas: HIV therapeutics and comorbidities in adults, maternal and pediatric prevention and treatment, biomedical prevention for adults and adolescents, and immune-based prevention for HIV and associated diseases. Each center will collaborate with statistical, data management, and laboratory centers to conduct high-impact implementation research and improve the uptake of evidence-based strategies. This initiative is governed by the Public Health Service Act and federal regulations to ensure the advancement of prevention and treatment research. The project falls under NAICS code 541715 and is managed by the Division of AIDS. The primary goal is to produce critical findings that significantly benefit individuals in the United States who are living with or are at risk for HIV and related diseases.
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The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance the National Institutes of Health (NIH) mission by supporting four Clinical Trials Networks (CTNs) each comprised of a Leadership and Operations Center (LOC), Statistical and Data Management Center, and Laboratory Center working with Clinical Trials Units to advance prevention, treatment, and implementation research designed to end the HIV epidemic. This NOFO will solicit applications for four LOCs to provide scientific leadership, research prioritization, and conduct studies in a CTN. A LOC develops the research agenda in one of these areas: 1) HIV therapeutics/cure, and prevention/treatment for HIV-associated comorbidities in adults; 2) HIV prevention/treatment in maternal/adolescent/pediatric populations; 3) biomedical HIV prevention strategies for adults/adolescents; and 4) immune-based prevention for HIV and HIV-associated diseases. CTNs will conduct HIV implementation research improving uptake of evidence-based prevention and treatment strategies across the lifespan. High impact LOC studies will produce crucial findings significantly benefiting Americans with or at-risk of HIV and HIV-associated diseases.
Grant authorities that allow NIAID to forecast this opportunity are: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.
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