This Government Contract opportunity from Department Of Health And Human Services was posted on May 19, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Preclinical Efficacy and Safety Testing

Closed

Federal

Submission Closed06/03/2026, 01:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541715

New

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Marshall Space Flight Center

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Armstrong Flight Research Center

POSTED

in 7 months

DEADLINE

N/A

AI Contract Overview

This contract involves conducting both in vitro and in vivo experiments to evaluate the tumor-killing effectiveness, potential off-target effects, and overall safety profile of an optimized T-cell receptor (TCR) using clear cell renal cell carcinoma (ccRCC) models and xenografts. The studies aim to generate essential preclinical data to support further development of the TCR for therapeutic applications. Issued by the National Institutes of Health under the Department of Health and Human Services, the work will be performed in Bethesda. It is designated as a subcontract opportunity under NAICS code 541715, which pertains to research and development services. The solicitation was posted in May 2026 with a response deadline in early June 2026. The contract focuses on generating robust efficacy and safety data crucial for advancing the candidate therapy toward clinical evaluation.

General Info

Evaluate optimized TCR efficacy, safety, and off-target effects in ccRCC models for therapeutic development.

Agency

Department Of Health And Human Services → National Institutes Of Health Olao

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) View NAICS

Place of Performance

Bethesda, MD, 20892, USA

Set-Aside

NONE

Documents

(0)

No documents available

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Timeline

PhaseClosed

PostedMay 19

subcontract

Response DeadlineJun 3

Deadline has passed

Submission Closed

06/03/2026, 01:00:00 PM UTC

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Organization & Contact Information

AgencyDepartment Of Health And Human Services → National Institutes Of Health Olao

ContactsNo contacts available

OfficeN/A

Organization / Agency

Department Of Health And Human Services → National Institutes Of Health Olao

Office AddressN/A

ContactsNo contact information available

Full Description

Conduct in vitro and in vivo studies to assess tumor-killing efficacy, off-target effects, and safety of the optimized TCR using ccRCC models and xenografts.