This Government Contract opportunity from Department Of Health And Human Services was posted on May 19, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Preclinical Efficacy and Safety Testing

Closed

Federal

Submission Closed06/03/2026, 01:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541715

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Advanced Driver Assistance Systems (ADAS), on road networks at the Fish and Wildlife Service’s (FWS) National Wildlife Refuges (NWR)

Solicitation # 6913G626Q300038

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6913G6 Volpe National Transportation System Cntr

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Synthetic Training Environment (STE) Virtual Software (VSW)

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DEADLINE

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Solicitation # HQ0860-25-S-C001

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Light Forces Enhancement

Solicitation # WS5642957262

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Department of Public Works and Government Services

POSTED

DEADLINE

R3PEATS Multi-Team Triangulation: Collaborative Cross-Method Approaches to Scientific Discovery (RM1)The R3PEATS Multi-Team Triangulation initiative, managed by the National Institutes of Health under the Department of Health and Human Services, focuses on collaborative cross-method approaches to scientific discovery. This program supports coordinated teams investigating central biomedical research questions using complementary populations, model systems, or methods. A primary objective is to enhance scientific excellence by identifying signal robustness and biological variability while integrating replication directly into the research design. This effort is part of the broader NIH Common Fund program dedicated to Rigor, Replicability, and Reproducibility to Promote Excellence, Accuracy, and Translation in Science. The opportunity is currently listed as a forecast with a posted date of September 11, 2026, and interested parties can contact the R3PEATS Program for further information.

National Institutes Of Health

POSTED

1 day ago

DEADLINE

N/A

AI Contract Overview

This contract involves conducting both in vitro and in vivo experiments to evaluate the tumor-killing effectiveness, potential off-target effects, and overall safety profile of an optimized T-cell receptor (TCR) using clear cell renal cell carcinoma (ccRCC) models and xenografts. The studies aim to generate essential preclinical data to support further development of the TCR for therapeutic applications. Issued by the National Institutes of Health under the Department of Health and Human Services, the work will be performed in Bethesda. It is designated as a subcontract opportunity under NAICS code 541715, which pertains to research and development services. The solicitation was posted in May 2026 with a response deadline in early June 2026. The contract focuses on generating robust efficacy and safety data crucial for advancing the candidate therapy toward clinical evaluation.

General Info

Evaluate optimized TCR efficacy, safety, and off-target effects in ccRCC models for therapeutic development.

Agency

Department Of Health And Human Services → National Institutes Of Health OlaoView Agency

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)View NAICS

Place of Performance

Bethesda, MD, 20892, USA

Set-Aside

NONE

Documents

This scope was carved out of 75N98026Q00392.

The full solicitation package (1 document), including the RFP, is on the prime solicitation, not on this scope.

View the prime solicitation

Modification to the A11 HERV-E TCR and T cell product to improve the therapeutic efficacy for ccRCC patients.

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Timeline

PhaseClosed

PostedMay 19

subcontract

Response DeadlineJun 3

Deadline has passed

Submission Closed

06/03/2026, 01:00:00 PM UTC

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Organization & Contact Information

AgencyDepartment Of Health And Human Services → National Institutes Of Health Olao

ContactsNo contacts available

OfficeN/A

Organization / Agency

Department Of Health And Human Services → National Institutes Of Health Olao

View Agency Profile

Office AddressN/A

ContactsNo contact information available

Full Description

Conduct in vitro and in vivo studies to assess tumor-killing efficacy, off-target effects, and safety of the optimized TCR using ccRCC models and xenografts.