This Government Contract opportunity from Department Of Defense was posted on May 6, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.
Reporter Cell Line Engineering
Contract Overview
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The contract seeks the design and construction of engineered cell lines capable of reporting specific DNA modifications through fluorescent or selectable markers, targeting advanced biological detection and monitoring capabilities. This effort is part of a subcontract under the Department of Defense, managed by the Defense Advanced Research Projects Agency, and falls under the NAICS code 541714 for research and development in biotechnology. The project requires the development of robust, reproducible cell systems that can dynamically indicate genetic alterations in real time, with potential applications in defense-related biological surveillance, genomic integrity assessment, or threat detection systems. Proposals must be submitted by June 24, 2026, and must demonstrate expertise in molecular biology, synthetic biology, and cell line engineering. The work will involve precise genetic modifications to link DNA damage or epigenetic changes to measurable outputs such as fluorescence induction or survival markers under selective pressure. Performance is expected to meet high standards of sensitivity, specificity, and scalability, with the goal of enabling field-deployable or laboratory-based systems for monitoring genomic instability. While no set-aside preferences or geographic restrictions are specified, applicants must be prepared to support defense-critical research objectives with minimal oversight and maximum technical innovation.
General Info
Agency
NAICS
Place of Performance
VASet-Aside
Documents
This scope was carved out of DARPA-SN-26-67.
The full solicitation package (2 documents), including the RFP, is on the prime solicitation, not on this scope.
Research Opportunity: DNA-Protein Epigenetic Chemistry Engineering (D-PECHE)
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Timeline
Submission Closed
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