This Government Contract opportunity from Department Of Health And Human Services was posted on August 24, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Specialized Software Integration for CLEM and Tomography

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Federal

Submission Closed09/03/2026, 01:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541715

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Federal

Machine Learning & Predictive Analytics Engineering

Naval Air Systems Command

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Digital Biomarker & Computational Modeling DevelopmentThis subcontract focuses on the development and validation of objective digital biomarkers and computational models to support prime contractors within the Defense Health Agency Alzheimer’s Research Program. The scope of work involves utilizing high-performance computing and AI/ML software frameworks to create algorithms for early disease detection and predictive models for disease forecasting. The project requires strict adherence to HIPAA compliance and FDA software validation standards to ensure the integrity and security of the delivered models. Performance will take place in Frederick, Maryland, with the primary objective of delivering validated digital biomarkers and predictive tools to the Department of Defense.

Defense Health Agency

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TBI & Psychological Health Research Services

Defense Health Agency

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Space Power and Reactor Capabilities (SPARC) - Sources Sought Notice

Solicitation # 80GRC026R0009_PS

NASA Glenn Research Center

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Atomically Precise Molecules (APM)

Solicitation # DARPA-PS-26-141

The Atomically Precise Molecules (APM) program, solicitation DARPA-PS-26-141, is a 36-month initiative by the DARPA Multi X Office seeking innovative synthesis techniques for programmable precision polymers (PPPs) and nonlinear optical (NLO) materials. The program aims to develop scalable materials with strictly controlled monomer sequences and compositions, culminating in a prototype NLO material integrated into a government-provided electro-optic modulator capable of achieving greater than 1THz modulation. The effort is structured in two phases, with Phase I lasting 12 months and focusing on synthesis capabilities. Research limited to inorganic materials or incremental improvements to existing state-of-the-art practices is specifically excluded. Awards will be issued as Other Transaction for Prototype Agreements, with payments processed through the Wide Area Workflow system based on a schedule of milestones. Proposals are due by December 18, 2026, via the Broad Agency Announcement Tool and must include technical, management, and pricing volumes. Eligibility is restricted to U.S. organizations, and all performers must comply with CMMC Level 2 self-certification and NIST SP 800-171 standards for safeguarding Controlled Unclassified Information. Evaluation will be based on technical approach, relevance to the DARPA mission, budget realism, and the capability to transition the technology to military or commercial sectors.

Defense Advanced Research Projects Agcy

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Sole Source to L3Harris ForceX, Inc | VAMPIRE Spares

Solicitation # SPRRA2-27-R-SP05

Al DLA Aviation At Huntsville

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A-- TREDS III supporting DOE, NNSA and NFO

Solicitation # 89233127RNA000340

Nnsa Non-Mo Cntrctng Operations Division

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Request for Proposal (RFP) - Resilient Missile Warning Tracking (RMWT) Low Earth Orbit (LEO) Ground Entry Points (GEPs)

Solicitation # FA240126R0003

The Space Development Agency is soliciting proposals under solicitation FA240126R0003 for the Resilient Missile Warning Tracking (RMWT) Low Earth Orbit (LEO) Ground Entry Points (GEPs) effort. This IDIQ contract, which has a ceiling of 369 million dollars, covers the detailed design, civil engineering, procurement, installation, integration, and maintenance of GEP sites at multiple globally dispersed locations. The scope of work specifically includes the delivery of communications shelters, RF antennas and electronics, optical terminals and electronics, networking equipment, and software, as well as the development of Test Ground Support Equipment and Auxiliary Development Units. The acquisition utilizes a best-value tradeoff source selection process where technical, management, and past performance factors are significantly more important than price. Proposals are due by 4:00 PM Eastern Time on November 23, 2026, and must be submitted in seven volumes via the DoD Secure Access File Exchange. The contract structure includes a base period from March 31, 2027, to March 30, 2028, with an option period extending to March 30, 2029, and an overall ordering period through September 30, 2031. Pricing is a mix of Firm-Fixed-Price for labor and materials and Cost-Reimbursable for other direct costs and travel. Key compliance requirements include adherence to CMMC Level requirements, safeguarding of covered defense information per DFARS 252.204-7012, and a minimum small business participation requirement of 5 percent for large business offerors. Contractors must also implement unique item identification based on MIL-STD-130 and follow MIL-STD-129 for shipment and storage labeling. All invoicing and payment processing will be conducted through the Wide Area WorkFlow system.

FA2401 Space Development Agency Sda

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Pioneering Aerospace Capabilities, Engineering and Research

Solicitation # FA2391-23-S-2403

The Pioneering Aerospace Capabilities, Engineering and Research (PACER) program, under solicitation FA2391-23-S-2403, is a comprehensive Broad Agency Announcement issued by the Air Force Research Laboratory (AFRL) Aerospace Systems Directorate. This open, two-step solicitation is designed to fund research and development efforts that mature novel aerospace concepts and technologies to appropriate technology readiness levels, specifically targeting transformative capabilities for the warfighter. The program encompasses a wide array of specialized calls, including efforts for hypersonic weapon concepts (HAMWC), automated air-to-air refueling (CRONUS), advanced propulsion and power systems (SNAPP, AEPO, MSIPPT, HITEMP, INNATE), and multidisciplinary design and structures (MASTR, VOLARE, CC DROIDS). The acquisition process typically involves an initial white paper submission followed by full proposals from selected offerors, though some calls utilize a one-step process. Awards may take the form of contracts or assistance instruments, with anticipated types including Cost Plus Fixed Fee (CPFF), Firm-Fixed-Price (FFP), and IDIQ task orders. Due to the sensitive nature of the research, strict security protocols are enforced, requiring offerors to comply with AFRLI 61-113 for Science and Technology Protection and meet CMMC Level 2 and NIST SP 800-171 standards to access Controlled Unclassified Information (CUI). Proposals are evaluated based on the uniqueness and innovation of the approach, understanding of scope, technical soundness, and transition potential, with cost realism serving as a secondary substantial factor.

FA2391 USAF Afmc Afrl Pzl Afrl Rqkp

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Technical Research, Engineering, and Development Services (TREDS) III supportin

Solicitation # 89233127RNA000340

Contracting Operations Division

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Statistical ExpertiseThis small business set-aside subcontract, titled Statistical Expertise, supports prime contractors on NIH/NHGRI projects within the Department of Health and Human Services. The scope of work involves providing advanced statistical analysis and design for clinical research protocols, specifically requiring expertise in SAS or R for statistical programming, sample size calculations, and the interpretation of trial results. Key deliverables include validated statistical outputs, final analysis reports, and Statistical Analysis Plans. The performance of this contract takes place in Bethesda and is subject to strict HIPAA compliance, necessitating a mandatory Business Associate Agreement. Interested parties should note the response deadline of November 13, 2026, and the classification under NAICS code 541715.

National Institutes Of Health Olao

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DEADLINE

Protocol Monitoring and Data Management SupportThis subcontract opportunity, titled Protocol Monitoring and Data Management Support, involves providing clinical trial protocol monitoring and research data management for prime contractors on NIH/NHGRI clinical research projects. The scope of work includes monitoring clinical research protocols, managing data services, and developing transition and startup documentation to deliver validated research datasets and monitored protocol reports. Performance will take place in Bethesda, and the project is categorized under NAICS code 541715. The contract is designated as a Total Small Business Set Aside for the National Institutes of Health under the Department of Health and Human Services. To ensure regulatory compliance, the selected provider must adhere to NIH ICO Information Security and Privacy certifications and execute a Business Associate Agreement for HIPAA compliance. Responses are due by November 13, 2026.

National Institutes Of Health Olao

POSTED

1 day ago

DEADLINE

in 17 days

AI Contract Overview

This subcontract opportunity, issued by the National Institutes of Health under the Department of Health and Human Services, focuses on the development and integration of specialized software for Correlative Light and Electron Microscopy and tomography. The project aims to implement automated 2D and 3D imaging capabilities, data registration, and multi-modal microscopy analysis to enhance scientific research. The work will be performed in Bethesda, Maryland, under NAICS code 541715. Interested parties must submit their responses by the deadline of September 3, 2026, at 1:00 PM.