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UNifying Imaging with QUantum Entanglement (UNIQUE) Proposers' Day

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ARPA-H-SN-26-162Federal

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The Advanced Research Projects Agency for Health (ARPA-H), through its Health Science Futures Office, has issued Special Notice ARPA-H-SN-26-162 to announce the UNifying Imaging with QUantum Entanglement (UNIQUE) program. This initiative aims to establish a new biomedical imaging paradigm by utilizing quantum-derived observables, specifically entangled or quantum-correlated 511 keV photon pairs, to reveal disease biology that is currently invisible to existing technologies. The program is divided into two primary technical areas: the Imaging Core, which focuses on the physical systems and detectors required to generate and measure quantum-derived imaging contrast, and Quantum AI Interpretation and Fusion, which focuses on developing AI-driven reconstruction methods to integrate these observables into multidimensional imaging representations. This special notice serves as an informational alert and does not constitute a formal solicitation. It announces a hybrid Proposers Day scheduled for October 15, 2026, to prepare the scientific community for an upcoming Innovative Solutions Opening (ISO) expected by September 18, 2026. Interested parties are invited to submit a single-slide lightning talk presentation via the designated teaming profile form by September 22, 2026, to showcase their capabilities and teaming goals. Technical inquiries are directed to Program Manager Wilfred Ngwa or the UNIQUE team via email.

General Info

ARPA-H UNIQUE program seeks quantum-derived biomedical imaging and AI reconstruction technologies.

Agency

Department Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)View Agency

NAICS

541714 - Research and Development in Biotechnology (except Nanobiotechnology)View NAICS

Place of Performance

DC

Set-Aside

NONE

Documents

(2)

ARPA-H-SN-26-162: UNIQUE Proposers’ Day Announcement

PDF•special-notice

UNIQUE Lightning Talk Template

PPTX•1 page•other

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Timeline

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)
Contacts1 person available
OfficeWashington, DC, 20005, USA
Organization / Agency
Department Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)
View Agency Profile
Office AddressWashington, DC, 20005, USA
Contacts
The UNIQUE Team
contact@example.gov

Full Description

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This Special Notice (SN) alerts the scientific community to a newly approved ARPA-H program and notifies potential proposers of an associated Proposers’ Day.


See attached UNIQUE-SN-ARPA-H-SN-26-162 for further details. A Lightning Talk Template is also provided for convenience. 


The exact location of the Proposers' Day is TBD and this SN will be amended with the location as soon as it is finalized.

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The Advanced Research Projects Agency for Health (ARPA-H), under the Department of Health and Human Services, has issued an Innovative Solutions Opening for the UNifying Imaging with QUantum Entanglement (UNIQUE) Program. This solicitation, identified as ARPA-H-SOL-26-162, seeks to establish multiple Other Transaction Agreements to advance imaging technologies through quantum entanglement. Interested parties must submit their responses by December 16, 2026. The procurement process includes a dedicated Proposers Day detailed in a separate special notice and a frequently asked questions page for ongoing updates. This opportunity is open to all qualified entities as there is no specific set-aside used for this solicitation. Primary inquiries and communications should be directed to the UNIQUE Team via the provided agency contact information.
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