Cancer Center Support Grants (CCSGs) for NCI-designated Cancer Centers (P30 Clinical Trial Optional)
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This funding opportunity invites applications for Cancer Center Support Grants (CCSGs) to support NCI-Designated Cancer Centers, which are categorized into three types: Comprehensive Cancer Centers, Clinical Cancer Centers, and Basic Cancer Centers. Comprehensive Centers demonstrate strong research activity in basic laboratory, clinical, and prevention/control research while fostering transdisciplinary collaboration. Clinical Cancer Centers primarily focus on some combination of these areas without the broader scope of Comprehensive Centers, while Basic Cancer Centers specialize exclusively in basic laboratory research. The grants aim to consolidate institutional cancer research capabilities into a unified, interdisciplinary research enterprise that crosses institutional boundaries. Supported Cancer Centers are expected to be key contributors to advancing knowledge about cancer and developing improved methods for prevention, diagnosis, and treatment. Additionally, they must develop Shared Resources to facilitate research, collaborate with other NCI-funded programs and researchers, and actively disseminate their findings to benefit the wider community. The grant application process is managed by the National Cancer Institute under the Department of Health and Human Services, and the opportunity was announced in March 2026. Applicants can seek further information via the Office of Cancer Centers at NCI.
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This Notice of Funding Opportunity (NOFO) invites applications for P30 Cancer Center Support Grants (CCSGs) to support NCI-Designated Cancer Centers. CCSGs support three types of Cancer Centers: 1) Comprehensive Cancer Centers, which demonstrate reasonable depth and breadth of research activities in each of three major areas: basic laboratory; clinical; and prevention, control and population-based research, and which have substantial transdisciplinary research that bridges these scientific areas; and 2) Clinical Cancer Centers, which are primarily focused on basic laboratory; clinical; and prevention, cancer control, and population-based research; or some combination of these areas, and 3) Basic Cancer Centers, which focus on basic laboratory research. The purpose of all types of NCI-Designated Cancer Centers is to capitalize on all institutional cancer research capabilities, integrating meritorious research into a single transdisciplinary research enterprise across all institutional boundaries. Cancer Centers supported through this NOFO are expected to serve as major sources of discovery of the nature of cancer and of development of more effective approaches to prevention, diagnosis, and therapy; to contribute significantly to the development of Shared Resources that support research; to collaborate and coordinate their research efforts with other NCI-funded programs and investigators; and to disseminate research findings for the benefit of the community.
