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Controlled Clinical Trials on Long-Term Effects of Nutritional Interventions on the Progression of Risk Factors for Age-Related Chronic Conditions Over the Life Span and Their Age of Onset

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The National Institute on Aging is forecasting a Notice of Funding Opportunity to support randomized controlled clinical trials investigating how nutritional interventions affect the progression of risk factors for age-related chronic conditions across the human life span. The goal is to better understand the long-term benefits and potential risks associated with various dietary practices and macronutrients to maintain health and delay the onset of morbidities. Because these studies require significant durations for enrollment and follow-up to provide sufficient evidence, the agency will allow proposed projects to last up to seven years. This opportunity will utilize the U19 activity code. While applications are not currently being accepted, this notice serves as a forecast to allow researchers to establish collaborations and develop projects before the official solicitation is published.

General Info

NIA to fund long-term clinical trials on nutrition's impact on age-related chronic conditions.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

N/A

Place of Performance

Not specified

Set-Aside

NONE

Documents

(0)

No documents available

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUSA
Organization / AgencyDepartment Of Health And Human Services → National Institutes Of Health
Office AddressUSA
Contacts
NIA Scientific Contact
contact@example.gov

Full Description

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The National Institute on Aging (NIA) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for randomized controlled clinical trials on long-term effects of nutritional interventions on the progression of risk factors for age-related chronic conditions over the life span and their age of onset.

Although considerable information is available on health benefits and risks of a variety of nutritional factors (e.g., macronutrients, overall caloric intake, differing nutrient sources) there remains a need for better understanding of long-term benefits and potential risks of differing nutritional factors and dietary practices to maintain health across the full range of the life span. Rigorous understanding of these effects requires long-term controlled clinical trials of preventive interventions in younger and/or older persons. Given the rates of risk factor progression in younger persons and of accumulation of morbidities in later life, many such trials will require long-term intervention durations and follow-up of at least 5 years to provide sufficient power and evidence of their long-term effects.  In order to support projects of sufficient duration to provide for start-up, enrollment, follow-up, and outcome data analyses in such trials, applications in response to this NOFO may propose projects of up to seven years in length.

Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO intends to utilize the U19 activity code. Investigators with expertise and insights into this area of aging research are encouraged to begin to consider applying for this new NOFO.

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