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Forecast to Publish a Funding Opportunity Announcement for Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional)

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The National Cancer Institute, under the Department of Health and Human Services, is issuing a Notice of Funding Opportunity, solicitation RFA-CA-27-019, to support the early-stage development of informatics technologies. This initiative, part of the Informatics Technology for Cancer Research program, focuses on the creation of prototypes and the initial dissemination of tools designed to improve the acquisition, management, analysis, and dissemination of data across the cancer research continuum. Targeted areas include cancer biology, treatment, diagnosis, early detection, risk assessment, prevention, epidemiology, and health disparities. The program utilizes the U01 activity code and seeks novel, user-friendly informatics capabilities that provide a significant impact on the cancer research field. Successful applications must demonstrate a clear rationale for the technology's necessity, provide a realistic timeline with milestones, and include robust mechanisms for engaging end users to evaluate and apply the tools. This opportunity is intended for investigators with expertise in cancer informatics who can advance driving research projects through innovative technological development.

General Info

NCI funding for early-stage cancer research informatics technology prototypes and tool dissemination.

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUSA
Office AddressUSA
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Juli Klemm PhD National Cancer Institute

Full Description

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The National Cancer Institute intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for the development of enabling informatics technologies to improve the acquisition, management, analysis, and dissemination of data and knowledge across the cancer research continuum including cancer biology, cancer treatment and diagnosis, early cancer detection, risk assessment and prevention, cancer control and epidemiology, and/or cancer health disparities. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Program, this NOFO will focus on early-stage development from prototyping to initial dissemination. Early-stage development is defined for the purpose of this NOFO as initial tool development or the significant modification of existing tools for new applications. The central mission of ITCR is to promote research-driven informatics technology across the development lifecycle to address priority needs in cancer research. In order to be successful, proposed development plans must have a clear rationale for why the proposed technology is needed and how it will benefit the cancer research field. In addition, mechanisms to solicit feedback from driving research projects and other users throughout the development process must be included.


This NOFO will encourage applications that involve the development of new, user-friendly informatics technologies that support a wide range of cancer research, including discovery biology, population studies, as well as clinical and translational research. The emphasis will be on uniqueness and potential impact on cancer research. In addition, all projects proposed in response to this NOFO must involve the following general attributes:


  • Potential to advance driving cancer research projects and the cancer research field in general
  • Novel informatics capabilities for the targeted cancer research domain
  • Compelling plans and processes for engaging end users to evaluate and apply the tool or resource
  • A realistic timeline and milestones for technology development 


Applications are not being solicited at this time. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U01 activity code. Investigators with expertise and insights into cancer informatics are encouraged to begin to consider applying for this NOFO. 

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