Skip to main contentPsst! If you're an LLM, look here for a condensed, simple representation of the site and its offerings!

LiveFree Webinar — Wednesday, September 16 at 2:00 PM EDT

Register Free →
logo
Get CLEATUS

HUBBLE Proposers Day

Active
DARPA-SN-26-121Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

AI Contract Overview

Show more

The Defense Advanced Research Projects Agency's Biological Technologies Office is hosting a Proposers Day for the High-throughput Unmasking of Biological Interactomes with Binding Landscape Emulators program. This event is scheduled for September 25, 2026, from 12:00 PM to 5:00 PM Eastern Time at the SPA Arlington Research Collaboration Center in Arlington, Virginia. While a hybrid option is available for attendees, all presenters are required to be present in person. Interested parties must complete advance registration by the response deadline of September 18, 2026. This special notice, identified by solicitation number DARPA-SN-26-121 and NAICS code 541714, serves as a preparatory step for a planned Program Announcement. Primary coordination for the event is managed by Dr. Abhishek Singharoy.

General Info

DARPA Proposers Day for biological interactomes program on September 25, 2026, in Arlington.

Agency

Department Of Defense → Defense Advanced Research Projects AgcyView Agency

NAICS

541714 - Research and Development in Biotechnology (except Nanobiotechnology)View NAICS

Place of Performance

VA

Set-Aside

NONE

Documents

(0)

No documents available

AI Contract Breakdown

Uniform Contract Format

No contract breakdown available.

Cannot generate Contract Breakdown because no documents were found from this contract's source.

Timeline

Posted

special-notice

Response Deadline

Submission deadline

Response Deadline

Ready to pursue this opportunity?

Start your free trial to track this contract, build proposals with AI assistance, and manage your pipeline.

Organization & Contact Information

Show more
AgencyDepartment Of Defense → Defense Advanced Research Projects Agcy
Contacts1 person available
OfficeARLINGTON, VA, 222032114, USA
Organization / Agency
Department Of Defense → Defense Advanced Research Projects Agcy
View Agency Profile
Office AddressARLINGTON, VA, 222032114, USA
Contacts
Dr. Abhishek Singharoy DARPA/BTO
contact@example.gov

Full Description

Show more
The Biological Technologies Office (BTO) of the Defense Advanced Research Projects Agency (DARPA) is hosting a Proposers Day for the potential proposer community in support of a planned Program Announcement (PA) for the “High-throughput Unmasking of Biological Interactomes with Binding Landscape Emulators” (HUBBLE) program. The Proposers Day will be held on September 25th, 2026 from 12:00 PM to 5:00 PM in person at the SPA Arlington Research Collaboration Center (SPARCC) at 4075 Wilson Blvd. Arlington, Virginia 22203. A hybrid option is available for those who are unable to travel for the event, however, all presenters must attend in person. Advance registration is required. Note: all times listed in this announcement and on the registration, website are in Eastern Time.

Similar Contracts

Same NAICS industry code

NAICS: 541714
New
Federal
Chemical, Biological, Radiological and Nuclear Advance Defense Enabling Network and Clinical Capability (CADENCC)
Solicitation # W911SR-26-9-CADENCC
The Department of the Army, through the Army Contracting Command and the Joint Project Lead Enabling Technologies, is seeking preproposals for the Chemical, Biological, Radiological and Nuclear Advance Defense Enabling Network and Clinical Capability (CADENCC). This initiative aims to accelerate clinical trial startups for CBRN defense readiness by implementing Master Protocols, decentralized trial technologies, and a pre-positioned clinical trial site network. The project will primarily focus on Phase I and Phase II clinical trials for pre-exposure prophylaxis, post-exposure prophylaxis, and early treatment products. This opportunity is issued under Other Transaction Authority (10 USC 4022) for the development of prototypes. Successful performers may be eligible for non-competitive follow-on production contracts. Preproposals are due by 1500 hours on September 17, 2026, and must be limited to 10 pages. Evaluation will be based on technical merit, military relevance, technology readiness level 4 or above, regulatory compliance with FDA guidelines, and overall best value. All prospective awardees must be registered in the System for Award Management.
W6QK Acc-Apg

POSTED

about 13 hours ago

DEADLINE

in 14 days
View Details
NAICS: 541714
New
Federal
Myocardial Intramural Remodeling by Transvenous tether (MIRTH) Implant Design Support and Feasibility Prototypes
Solicitation # 75N98026Q01129
The National Institutes of Health Nhlbi, under the Department of Health and Human Services, is seeking a contractor for the Myocardial Intramural Remodeling by Transvenous tether (MIRTH) Implant Design Support and Feasibility Prototypes project. This presolicitation, identified by solicitation number 75N98026Q01129, falls under NAICS code 541714 and focuses on the design and prototyping of medical implants. The project will be performed in Bethesda, Maryland. Interested parties must submit their responses by the deadline of September 10, 2026, at 4:00 PM. Primary inquiries and coordination for this effort are managed by Noelle Decenzo.
National Institutes Of Health Nhlbi

POSTED

about 13 hours ago

DEADLINE

in 7 days
View Details
NAICS: 541714
New
Federal
Sole Source Chapter PomePlex-26 NGS Assay (96 tests)
Solicitation # 1173878
The Department of Agriculture, through the Animal and Plant Health Inspection Service, is issuing a sole source notification for the acquisition of 10 ChapterDx PomePlex 26 kits. This technology is required for the Plant Germplasm Quarantine Program to streamline the screening of 26 viruses and viroids in pome trees, replacing a laborious individual PCR process with a single tube reaction. Each kit provides reagents for 96 individual samples, supporting a project funded by the Plant Protection Act PPA7721 Spending plan for FY26. ChapterDx is identified as the only provider offering a 26 NGS assay compatible with existing laboratory workflows that allows for sequencing in a 96 sample format using minimal sample volumes. This procurement is designated as a Total Small Business Set Aside under NAICS code 541714. The notice is managed by Todd Bierl and closes on September 7, 2026, at 12:00 PM CST.
Ppq Beltsville Md

POSTED

1 day ago

DEADLINE

in 4 days
View Details
NAICS: 541714
New
Federal
Illumina DRAGEN GCP Lvl 4 1-year License
Solicitation # 75N98026Q01035
The National Institutes of Health, through the National Institute of Neurological Disorders and Stroke, is seeking a 12-month subscription to the Illumina DRAGEN GCP Level 4 platform under solicitation 75N98026Q01035. This contract is intended to support neurodegenerative disease research by processing approximately 1,300,000 GB of whole-genome sequencing data from 10,000 human genomes. The platform must provide graph-based alignment to the hg38 human reference genome and ensure accurate detection of single-nucleotide variants, insertions, deletions, structural variants, copy number variants, and repeat expansions. The selected contractor must ensure full compatibility with Illumina-generated sequencing data and existing DRAGEN-processed datasets, delivering outputs in CRAM and VCF file formats. This procurement is contemplated as a sole-source action to Illumina, Inc., with a total estimated cost of 113,004 dollars. The period of performance is 12 months, and the requirement is managed by the Department of Health and Human Services in Bethesda, Maryland.
National Institutes Of Health Olao

POSTED

1 day ago

DEADLINE

in 7 days
View Details
NAICS: 541714
New
Federal
Sepsis Research Blood Sample Collection Services
Solicitation # HT942523P0084
The Defense Health Agency, on behalf of the Walter Reed Army Institute of Research Integrative Systems Biology Branch, intends to award a sole source cost reimbursement research and development contract to Medstar Health Research Institute. This initiative focuses on the collection of blood samples and longitudinal clinical data from septic and non-septic burn patients to refine and validate the SeptiBurnAlert program. The government is transitioning this requirement from a firm-fixed-price award to a cost-type contract to better align with research needs. Medstar Health Research Institute is identified as the only technically acceptable vendor because they are currently recruiting subjects and collecting samples under an approved Institutional Review Board protocol. While this is a notice of intent to sole source, the government will consider capability statements from other interested parties to determine if competitive procurement is in its best interest. All submissions must be delivered to the primary point of contact by October 15, 2026.
Defense Health Agency

POSTED

3 days ago

DEADLINE

in about 1 month
View Details
NAICS: 541714
New
Federal
Trusted Partner Program Coming Soon - Update
Solicitation # W911NF26RA009
The Trusted Partner Program (TPP), under solicitation W911NF-26-R-A009, is a quick-reaction contracting vehicle designed to facilitate rapid Research, Development, Technology, and Evaluation (RDT&E) between the U.S. Army, Joint Warfighter partners, and external academic or non-profit research institutions. The program focuses on sensitive projects across core technical fields including biology, material science, electronics, chemistry, information sciences, and physics, as well as interdisciplinary areas such as applied AI, quantum battlefield dominance, and hypersonics. The government intends to award one or more Indefinite Delivery/Indefinite Quantity (ID/IQ) contracts with a base ordering period of five years and a potential five-year extension. Each awardee will have a total contract ceiling of 400 million dollars. The solicitation is currently on hold pending a review of Army priorities, which may lead to updates in the final Request for Proposals (RFP). Eligibility is restricted to institutes of higher education and non-profit research institutions, requiring CMMC Program Level 2 certification and the ability to handle various security classifications, ranging from Controlled Unclassified Information (CUI+) to Top Secret and Special Access Programs (SAP). Awards will be based on a best-value trade-off process, with technical capability being the most important factor, followed by management, past performance, small business participation, and cost. Proposals must include a specific technical expertise matrix and a video pitch demonstrating secure facilities. All invoicing and payments will be processed through the Wide Area WorkFlow (WAWF) system.
W6QK Acc-Apg Durham

POSTED

4 days ago

DEADLINE

N/A
View Details
NAICS: 541714
New
Federal
Q301--Strand-Specific RNA-Sequencing Services
Solicitation # 36C24126Q0788
Solicitation 36C24126Q0788 is a firm-fixed-price request for quotation issued by the Department of Veterans Affairs, Network Contracting Office 1, to obtain strand-specific RNA-sequencing services for the VA Bedford Healthcare System. This requirement is 100 percent set aside for small business concerns under NAICS 541714. The project involves the sequencing of 269 government-furnished human choroid plexus total RNA samples to support research on neurodegenerative diseases, including Alzheimer’s Disease and Chronic Traumatic Encephalopathy. The selected contractor must perform sample quality-control assessment, strand-specific rRNA depletion-based library preparation, and Illumina paired-end 2x150bp sequencing at a depth of 60 million read pairs per sample. The period of performance is one year from the date of award, with a strict turnaround requirement to complete all services and deliver final FASTQ files and quality-control reports within 23 to 28 business days after receiving the samples as a single batch. Data delivery is primarily required via physical hard drive, though secure electronic delivery may be authorized. Technical acceptability is based on the contractor's ability to meet specific quality standards, including a Phred quality score of Q30 or greater for at least 85 percent of bases. Award will be granted to the responsible quoter submitting the lowest-priced technically acceptable quotation. Quotations, including a technical capability statement of no more than five pages, must be submitted to the contracting office by September 10, 2026.
241-NETWORK Contract Office 01 (36C241)

POSTED

4 days ago

DEADLINE

in 7 days
View Details
NAICS: 541714
New
Federal
System Integration and Installation Support
Usuhs

POSTED

7 days ago

DEADLINE

in 5 days
View Details
NAICS: 541714
SBIR / STTR
Autonomous Navigation & Control Systems DevelopmentThe Defense Advanced Research Projects Agency under the U.S. Department of Defense is seeking a subcontract for the development of autonomous navigation and control systems. The project focuses on the design and simulation of navigation algorithms specifically for underwater vehicles operating in GPS-denied environments, utilizing a combination of acoustic, inertial, and environmental sensing technologies. This opportunity is designated as a Total Small Business Set-Aside under the SBIR/STTR mandate for companies with fewer than 500 employees, falling under NAICS code 541714. The solicitation was posted on August 26, 2026, with a response deadline of September 23, 2026.
Defense Advanced Research Projects Agency

POSTED

9 days ago

DEADLINE

in 20 days
View Details
NAICS: 541714
Federal
Preclinical Assessment of Naloxone Adequacy to Reverse Polysubstance Use-Induced Respiratory Depression — In Vivo Validation
Solicitation # 75F40126Q00382
The U.S. Food and Drug Administration is issuing a sole source, firm-fixed-price contract to Charles River Laboratories for a twelve month preclinical study. The research aims to evaluate the efficacy of naloxone and alternative reversal agents in treating respiratory depression caused by polysubstance use, specifically addressing the prevalence of fentanyl adulterated with xylazine, d-methamphetamine, or alprazolam. The study will utilize male CD rats to simultaneously measure respiratory and cardiovascular changes, as these systems are closely linked during drug-induced respiratory failure. The project consists of a four-phase in vivo study involving surgically instrumented animals. Key tasks include using whole body plethysmography for respiratory monitoring and implanted telemetry for continuous cardiovascular data collection. The contractor is responsible for collecting blood samples at five prespecified time points for pharmacokinetic analysis to be performed by the FDA. All work will be conducted in an AAALAC-accredited facility under non-GLP conditions, with statistical analysis performed via ANOVA.
FDA Office Of Acq Grant Svcs

POSTED

9 days ago

DEADLINE

in 7 days
View Details
NAICS: 541714
SBIR / STTR
Universal Cell Culture Platform for Rapid Establishment of Species-Agnostic Cell Lines and Autonomous Culture Operations
Solicitation # DPA26BZ05-DV020
Defense Advanced Research Projects Agency

POSTED

9 days ago

DEADLINE

in 20 days
View Details
NAICS: 541714
Grant
Clinical Research with Human SubjectsThe Department of Defense, through the Defense Health Agency Contracting Activity, is seeking a subcontractor for the design and execution of clinical research involving human subjects or human biospecimens. The scope of work encompasses critical research operations, including ensuring IRB compliance, managing participant recruitment, overseeing data management, and maintaining strict adherence to PHS inclusion standards. This opportunity is categorized under NAICS code 541714 and was posted on August 26, 2026. Interested parties must submit their responses by the deadline of November 4, 2026.
Defense Health Agency Contracting Activity - Dhaca

POSTED

9 days ago

DEADLINE

in 2 months
View Details

More opportunities from Department Of Defense → Defense Advanced Research Projects Agcy

Same awarding agency

NAICS: 541715
New
Federal
Selective Harnessing of Intrinsic Neuroplasticity Engineering (SHINE)
Solicitation # DARPA-PA-25-07-06
The Selective Harnessing of Intrinsic Neuroplasticity Engineering (SHINE) program, issued by the DARPA Defense Sciences Office under solicitation DARPA-PA-25-07-06, seeks innovative basic and applied research to selectively induce adaptive neuroplasticity within specific brain cell-types, regions, or circuits. This 18-month effort is divided into two tracks: Track A focuses on translationally mature technologies aimed at imminent clinical trials, requiring a therapeutic index of 5 or greater and the use of quantitative biomarkers such as fMRI or PET. Track B targets foundational, high-risk concepts ready for animal testing, requiring a spatial containment threshold exceeding 90 percent. All awards will be executed as Other Transaction (OT) for Prototype Agreements with a maximum value of 2,000,000 dollars per award, including any performer cost share. The program follows a synchronized timeline starting in January 2027, featuring a critical evaluation point at month 9 to assess progress through technical data and site visit demonstrations. Proposers must adhere to strict cybersecurity requirements, including a current CMMC status and annual affirmation posted in the Supplier Performance Risk System. Additionally, University Affiliated Research Centers acting as primes or subawardees must provide an organizational conflict of interest mitigation plan, and FFRDCs must certify that their proposed work is unavailable from the private sector. Proposals must be submitted as zip files via the DARPA BAA T Portal by October 9, 2026, utilizing the required Task Description Document templates and the Streamlined Cost Buildup Workbook.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

about 13 hours ago

DEADLINE

in about 1 month
View Details
NAICS: 812930
New
Federal
Notice of Intent to Award a Sole Source Contract - Parking Garage Services
Solicitation # HR001126QE004
The Defense Advanced Research Projects Agency (DARPA) intends to award a sole-source, firm-fixed-price contract to Arlington VA I FGF LLC for secure, controlled parking and facility support services. The contract covers the below-grade structured parking garage located at 675 N. Randolph Street in Arlington, Virginia, which is physically integrated directly beneath the DARPA Headquarters. This procurement is necessary because previous parking and access-control services were managed under a master lease by Washington Headquarters Services and will no longer be included in that structure. The scope of services includes structural maintenance and the support of mechanical, ventilation, fire, life-safety, and emergency infrastructure systems to ensure the facility remains safe and operational. DARPA has identified Arlington VA I FGF LLC as the only responsible source because they own the property and control the essential building systems. This sole-source approach is critical to maintaining physical security and avoiding operational disruptions, as the facility must comply with Department of Defense antiterrorism standards for subterranean structures.
Parking Lots and Garages

POSTED

1 day ago

DEADLINE

in 14 days
View Details
NAICS: 541715
New
Federal
Next Generation Hypersonic Cruise Missile Industry Day
Solicitation # DARPA-SN-26-120
The Defense Advanced Research Projects Agency Tactical Technology Office is hosting an Industry Day for the Next Generation Hypersonic Cruise Missile program on September 22, 2026, in Arlington, Virginia. This event, identified by special notice DARPA-SN-26-120, is designed to brief potential proposers on program objectives ahead of a planned Program Solicitation. Interested parties must complete advance registration by September 16, 2026, and should adhere to specific guidelines regarding security, controlled unclassified information, and poster submissions. This notice is intended for information and planning purposes only and does not constitute a formal solicitation or request for information. The event falls under NAICS code 541715 and is managed by the TTO Acquisition Team. For formal submissions, interested parties are referred to RFI DARPA-SN-26-93.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

1 day ago

DEADLINE

in 13 days
View Details
NAICS: 541715
New
Grant
Information Processing Techniques Office Office-Wide
Solicitation # HR001126S0011
Solicitation HR001126S0011 is a Broad Agency Announcement issued by the Defense Advanced Research Projects Agency's Information Processing Techniques Office to solicit revolutionary research ideas that provide decisive computational advantages. The program focuses on three primary thrust areas: AI Innovation and Execution, specifically energy-efficient and trustworthy AI for the network edge; Inherent Security and Privacy for adaptable systems; and Resilient Megasystems, utilizing machine-derived models to identify risks in complex interconnected systems. The agency is seeking advances that are significantly beyond the current state-of-the-art rather than evolutionary improvements. Awards may be granted through various instruments, including procurement contracts, grants, cooperative agreements, and Other Transaction agreements. Proposals are evaluated based on alignment with IPTO thrust areas, technical originality, operational realism, and the appropriateness of the project timetable and resource requirements. Submissions must follow a strict format, starting with a required abstract of no more than five pages. All proposers must maintain an active SAM.gov Unique Entity Identifier. For those submitting classified proposals, strict adherence to DoD security manuals and facility clearance requirements is mandatory, with specific protocols for electronic and hard-copy transmission. Additionally, procurement contracts are subject to CMMC Level 2 requirements per DFARS 252.204-7021, and University Affiliated Research Centers must provide an organizational conflict of interest mitigation plan.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

1 day ago

DEADLINE

in 10 months
View Details
NAICS: 541715
New
Federal
Perrseus
Solicitation # DARPA-PS-26-127
The Defense Advanced Research Projects Agency (DARPA) Multi X Office is soliciting proposals under solicitation DARPA-PS-26-127 for the Perrseus program. The objective is to develop architectures and processes for microscale ultra-high-vacuum (uUHV) packages with pressures less than 10^-10 mbar. These systems must integrate cold-atom neutral/ion quantum sensors, MEMS, and photonic sensors, focusing on reducing size, weight, and power (SWaP) while enabling high-volume manufacturing. The program emphasizes the interplay between housing materials, bonding processes, electrical/optical interconnects, atomic sources, and measurement techniques. Awards will be issued as Other Transaction for Prototype Agreements under 10 U.S.C. 4022, with a performance period consisting of a 24-month base phase and an 18-month option phase. Proposals are evaluated based on overall scientific and technical merit, potential contribution to the DARPA mission and national security technology base, and budget, price, and schedule, in that order of importance. Submissions must be made via the Broad Agency Announcement Tool (BAAT) by September 23, 2026. The selection process includes a review of written volumes and a 30-minute oral presentation followed by a 45-minute Q&A session. Prime performers must be commercial or private sector entities; FFRDCs, UARCs, and government entities may only participate as subcontractors if they provide unique capabilities. Strict security and compliance requirements are in place, including mandatory CMMC Level 2 (Self-Assessment) status posted in the Supplier Performance Risk System (SPRS) and adherence to DFARS 252.204-7012 and NIST 800-171 for safeguarding Controlled Unclassified Information (CUI). All participating U.S. Permanent Residents and Foreign Nationals must submit a DARPA eForm 60. Additionally, proposers must disclose any organizational conflicts of interest and are prohibited from teaming with any entity serving as an Independent Verification and Validation partner for the program.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

3 days ago

DEADLINE

in 20 days
View Details
NAICS: 541611
New
Federal
Technical Consultant
Administrative Management and General Management Consulting Services

POSTED

4 days ago

DEADLINE

in 10 months
View Details
NAICS: 339111
New
Federal
Specialized Facility/Laboratory Provider
Laboratory Apparatus and Furniture Manufacturing

POSTED

4 days ago

DEADLINE

in 10 months
View Details
NAICS: 541715
New
Federal
University Research Partner (Academic Sub-Awardee)
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

4 days ago

DEADLINE

in 10 months
View Details
NAICS: 541715
New
Federal
Subject Matter Expert (SME) / Research Sub-Awardee
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

4 days ago

DEADLINE

in 10 months
View Details
NAICS: 541715
New
Federal
TTO Office-Wide Solicitation 2026
Solicitation # DARPA-PS-26-123
The Defense Advanced Research Projects Agency Tactical Technology Office is issuing solicitation DARPA-PS-26-123 to accelerate the development of new platforms and weapons that provide overwhelming advantages across all warfighting domains. The scope of work focuses on innovative research and development in areas including advanced munitions, novel propulsion technologies, advanced autonomy, and new naval and aerospace platforms. This opportunity utilizes Other Transaction Award Agreements, offering a flexible alternative to standard federal contracts to foster rapid technological advancement and prevent technological surprise. Proposers must follow a multi-stage submission process starting with a two-page abstract, followed by a full proposal using a mandatory 25-page template and an official encouragement letter from DARPA. Evaluation is based on overall scientific and technical merit, potential contribution to the national security technology base, and cost realism. Strict security requirements are in place, including CMMC Level 2 self-assessment, compliance with NIST SP 800-171 Rev 2, and adherence to ITAR and EAR export controls. Classified submissions must be handled through specific secure channels as detailed in the solicitation attachments. All unclassified submissions must be uploaded as a single zip file not exceeding 100 MB by the response deadline of June 17, 2027.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

4 days ago

DEADLINE

in 10 months
View Details
NAICS: 541690
New
Federal
Technical Reporting & Data Analysis
Other Scientific and Technical Consulting Services

POSTED

7 days ago

DEADLINE

in 12 months
View Details
NAICS: 444190
New
Federal
Specialized Equipment & Material Supply
Other Building Material Dealers

POSTED

7 days ago

DEADLINE

in 12 months
View Details