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Metabolic Stability and Plasma Protein Binding Analysis

Active

Federal

Response Deadline09/19/2026, 01:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

General Info

Agency

Department Of Health And Human Services → National Institutes Of Health OlaoView Agency

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)View NAICS

Place of Performance

Bethesda, MD, 20892, USA

Set-Aside

NONE

Documents

This scope was carved out of 75N98026Q01193ENAMINEUSINCPCANIAAA08396.

The full solicitation package (1 document), including the RFP, is on the prime solicitation, not on this scope.

View the prime solicitation

Assay Service for assessing ADME properties and in vivo PK properties with the selected vendor. ENAMINE US INC

AI Contract Breakdown

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No contract breakdown available.

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Timeline

PostedSep 10

subcontract

Response DeadlineSep 19

Submission deadline

Response Deadline

09/19/2026, 01:00:00 PM UTCin 8 days

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health Olao

ContactsNo contacts available

OfficeN/A

Organization / Agency

Department Of Health And Human Services → National Institutes Of Health Olao

View Agency Profile

Office AddressN/A

ContactsNo contact information available

Full Description

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Performs metabolic stability and protein binding assays for prime contractors on NIAAA projects. Conducts hepatic microsomal stability testing for metabolic clearance, plasma protein binding assays for free fraction determination, and plasma stability testing for half-life evaluation. Utilizes hepatic microsomes and LC-MS/MS for quantification. Requires bioanalytical testing certification. Delivers analytical reports on microsomal half-life and intrinsic clearance.

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