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MPS & Organoid Development and Fabrication

Active
Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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This subcontract under the Advanced Research Projects Agency for Health (ARPA-H) focuses on the development and mass production of microphysiological systems (MPS) and organoids for prime contractors involved in COSMOS projects. The scope of work involves sourcing primary human cells and induced pluripotent stem cells from healthy donors to fabricate 3D microfluidic devices that replicate organ conditions. These systems are specifically designed for scaling production to support LEO Twin MPS and organoids. The project requires specialized expertise in iPSC differentiation and 3D cell culture to deliver validated cohorts of MPS and organoids for both terrestrial and low Earth orbit testing. This opportunity was posted on September 16, 2026, with a response deadline of October 7, 2026, falling under NAICS code 541715.

General Info

ARPA-H subcontract for mass producing microphysiological systems and organoids for COSMOS projects.

Agency

Department Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)View Agency

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)View NAICS

Place of Performance

DC

Set-Aside

NONE

Documents

This scope was carved out of ARPA-H-SOL-26-165.

The full solicitation package (8 documents), including the RFP, is on the prime solicitation, not on this scope.

View the prime solicitation

ARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions Opening

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)
ContactsNo contacts available
OfficeN/A
Organization / Agency
Department Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)
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Full Description

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Develops and mass-produces microphysiological systems (MPS) and organoids for prime contractors on ARPA-H COSMOS projects. Sources primary human cells/iPSCs from healthy donors, fabricates 3D microfluidic devices replicating organ conditions, and scales production for LEO Twin MPS and Organoids. Requires expertise in iPSC differentiation and 3D cell culture. Delivers validated MPS and organoid cohorts for terrestrial and LEO testing.

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