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NIDDK Multi-Purpose Resource-Related, Multi-Component Research Services Centers Cooperative Agreement (U2C - Clinical Trial Optional)

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Contract Overview

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The NIDDK Multi-Purpose Resource-Related Research, Multi-Component Centers Cooperative Agreement (U2C) seeks to establish centers that provide specialized, high-quality research support services to external investigators and consortia who lack access to such expertise in-house. These centers are designed to enhance research rigor, reproducibility, and cost efficiency by offering nationally recognized technical services, consulting, data coordination, and training in areas aligned with NIDDK’s mission, including integrative physiology, metabolic phenotyping, nutrition, community engagement, and data management. Services must primarily serve clients at other institutions, ensuring broad national impact rather than internal use. Disease focus should center on conditions such as obesity and diabetes, and each center must include experiential training components to build capacity in the research community. While clinical trials are not permitted, optional pilot and feasibility grant programs may be included to expand program reach and innovation. The opportunity is administered by the National Institutes of Health under the Department of Health and Human Services, with oversight from the Division of Diabetes, Endocrinology and Metabolic Diseases. It is posted as a forecast with an anticipated application window beginning July 1, 2026, and no set-aside or NAICS codes are specified. Applicants will engage through the NIH Grants.gov portal and should direct inquiries to the designated contact at niddk_dem@nih.gov. The structure of the U2C center should emphasize scalability, accessibility, and sustainability of core services, ensuring long-term value for the research community. There is no requirement for a specific geographic location for performance, and applicants may tailor the center’s components to address regional or national gaps in research infrastructure.

General Info

Establish multi-component research centers offering specialized services, training, and data support for diabetes and obesity research nationwide.

Agency

Department Of Health And Human Services → National Institutes Of HealthView Agency

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) View NAICS

Place of Performance

Not specified

Set-Aside

NONE

Documents

(0)

No documents available

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Timeline

Posted

forecast

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUS
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health
View Agency Profile
Office AddressUS
Contacts
Division of Diabetes Endocrinology and Metabolic Diseases

Full Description

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This Notice of Funding Opportunity (NOFO) announcement invites applications for NIDDK Multi-Purpose Resource-Related Research, Multi-Component Centers Cooperative Agreement (U2C - Clinical Trial Not Allowed).  To help increase rigor, reproducibility and cost efficiencies, U2C centers offer highly specialized cores that provide a range of topic focused services including but not limited to hands-on technical services, consulting, research/data coordination, or other research support services provided by nationally recognized experts.  In contrast to other types of Core Centers, the U2C services should be largely provided to clients located at another institution where the needed service or expertise is not available.  Provided services enable high impact research within NIDDK’s research mission including but not limited to integrative physiology, metabolic phenotyping, nutrition, community engagement, communications, and/or data and research coordination.  The disease focus should similarly be within NIDDK’s mission, such as obesity and diabetes. The clients for these services can be a consortia, research partners or individual investigators and should offer experiential training in at least one of the provided services. Applications to this NOFO can propose optional opportunities and/or a pilot and feasibility grant program depending on the needs of the program.

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