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Clinical Data Ecosystem for Genomics (CDEG)

Active
Grant

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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The National Human Genome Research Institute (NHGRI) plans to issue a Notice of Funding Opportunity (NOFO) aimed at reducing barriers to the development of a Clinical Data Ecosystem for Genomics (CDEG). This initiative seeks to establish a network focused on identifying, sharing, and improving methods for the clinical integration and sharing of genome sequencing data and its structured interpretation across laboratories, healthcare providers, and patients. The project will involve creating a pilot ecosystem demonstrating best practices for sharing genomic structured data in diverse healthcare environments, including primary care, and the development of standardized APIs to facilitate data access. Additionally, it aims to produce open-source clinical software and databases utilizing these APIs, showcase the ecosystem’s ability to maintain patient genomic data access as individuals move across healthcare systems, and refine these processes into practical implementation resources for wider adoption. Although applications are not currently being accepted, this announcement provides advance notice to allow prospective applicants time to form collaborations and develop responses. The funding opportunity will use the U01 activity code and invites investigators with expertise in genomic medicine, implementation science, computational genomics, data science, electronic health records, genomic data standards, cloud/database development, health information exchange, and clinical genomics integration to consider applying. The program is managed by the NHGRI under the Department of Health and Human Services, with Jennifer Troyer serving as the point of contact. The goal is to foster multidisciplinary collaboration to overcome existing hurdles in clinical genomic data sharing, thereby enhancing patient care and data interoperability across healthcare settings.

General Info

NHGRI will fund a pilot Clinical Data Ecosystem for standardized genomic data sharing and integration.

Agency

Department Of Health And Human Services → National Institutes Of HealthView Agency

NAICS

541713 - Research and Development in NanotechnologyView NAICS

Place of Performance

Not specified

Set-Aside

NONE

Documents

(0)

No documents available

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Timeline

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUSA
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health
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Office AddressUSA
Contacts
Jennifer Troyer National Human Genome Research Institute (NHGRI

Full Description

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The National Human Genome Research Institute (NHGRI) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for research reduce barriers to a Clinical Data Ecosystem for Genomics (CDEG) by establishing a network to identify, share, and improve approaches for clinical integration and sharing of genome sequencing data and their interpretation as structured data among labs, health care providers, and patients. Specifically, the Network will: 1) establish a pilot ecosystem that demonstrates best practices for the sharing of genomic structured data (GSD) across different health care settings, including primary care; 2) create standardized application programming interfaces (APIs) to support access to such data; 3) develop open-source clinical software applications and databases that utilize these APIs; 4) demonstrate the ability of the pilot ecosystem to overcome barriers to accessing patient genomic data as patients travel across healthcare systems; and 5) refine and develop these practices into implementation resources for broader sharing and adoption. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U01 activity code. Investigators with expertise and insights into this area of genomic medicine and implementation science are encouraged to begin to consider applying for this new NOFO. In addition, collaborative investigations combining expertise in computational genomics and data science, electronic health records (EHR), genomic data standards, cloud and database development, health information exchange, and implementing genomics in clinical care will be encouraged and these investigators should also begin considering applying for this application. 

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