Development of Candidate Medical Countermeasures (MCMs) and Technologies Against Chemical or Radiation/Nuclear (CRN) Threats
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The National Institutes of Health, through the National Institute of Allergy and Infectious Diseases, is seeking to support research and the development of medical countermeasures and technologies to address civilian radiation and chemical threats. This initiative is divided into two primary programs: the Radiation and Nuclear Research Program, which focuses on radiation-focused models, biomarkers, and injury prediction devices, and the Chemical Countermeasures Research Program, which emphasizes preclinical work on products to treat injuries from government-designated Chemicals of Concern in mass casualty settings. The goal of this effort is to advance the ability to diagnose, mitigate, and treat both acute and delayed effects of these exposures during public health emergencies. This forecast is administered under the authority of the Public Health Service Act and relevant federal regulations, targeting the development of products that improve survival and reduce morbidity across multiple organ systems.
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The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance the NIH mission by supporting research on concepts and technologies to address civilian radiation or chemical threats. Research is administered by NIAID on behalf of NIH via the Radiation and Nuclear (RNCP), and the Chemical Countermeasures (CCRP) Research Programs. A shared congressional mandate to the NIH OD (119 Stat. 2850; Public Law 109-149-Dec. 30, 2005), supports research to develop new ideas and technologies to diagnose, mitigate, and treat acute and delayed effects of radiation or chemical exposures during and after a public health emergency.
RNCP: Supports development of radiation-focused models, biomarkers of damage, devices to assess and predict injury, and products to improve survival and reduce morbidity across multiple organ systems.
CCRP: Supports preclinical work on products to mitigate and treat injuries after exposure to government-designated Chemicals of Concern. Candidates with efficacy in a post-exposure, civilian mass casualty setting are sought.
Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.
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