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Early-Onset Cancers: Investigating Etiology, Mechanisms, and Early Detection Strategies (RP1 Clinical Trials Optional)

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Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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The National Cancer Institute (NCI) is seeking applications for research focused on the etiology and underlying biological mechanisms of sporadic non-hereditary early-onset cancers (EOCs) occurring in individuals aged 18 to 49. The goal is to better understand the unexplained rise in cancer incidence among young adults and to inform strategies for prevention and control. Research proposals are encouraged to explore modifiable exposures contributing to increased EOC incidence, how these factors vary across different patient demographics, the biological mechanisms and host responses involved, and improved methods for identifying those at higher risk of developing these cancers. This funding opportunity consolidates both exploratory and research project mechanisms to simplify the application process and ensure continuity in investigation within this urgent area. Applicants may choose to submit either an exploratory or developmental research project with a maximum duration of two years or a full research project lasting four to five years. Clinical trials are optional within this funding opportunity, which is issued by the National Institutes of Health under the Department of Health and Human Services. The Epidemiology and Genomics Research Program serves as the point of contact for inquiries.

General Info

Funding for research on causes, biology, and prevention of early-onset sporadic cancers in young adults.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) View NAICS

Place of Performance

Not specified

Set-Aside

NONE

Documents

(0)

No documents available

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Timeline

Posted

forecast

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUS
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health
Office AddressUS
Contacts
Epidemiology and Genomics Research Program
contact@example.gov
+1 (555) 000-0000

Full Description

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Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) invites applications that investigate the etiology of sporadic non-hereditary early-onset cancers (EOCs: ages 18 to 49 years) and the underlying biological mechanisms that play a role in these cancers to inform prevention and control strategies. The proposed research is expected to advance the understanding of the unexplained rise of cancers in young adults. More specifically, studies should address one or more of the following: i) what modifiable exposures are driving the increase in the incidence of non-hereditary EOCs, and how do these factors vary by patient demographics? (ii) what biological mechanisms and host responses underly the increase in EOCs? and (iii) how can those at increased risk for developing EOCs be identified more effectively?

This NOFO consolidates exploratory/developmental and research project funding mechanisms to streamline the application process and sustain momentum in this critical research area. Applicants have the option of submitting either an exploratory/developmental research project with a project period of up to 2 years or a research project with a project period of 4 to 5 years.

 

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