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Early-Onset Cancers: Investigating Etiology, Mechanisms, and Early Detection Strategies (RP1 Clinical Trials Optional)

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Contract Overview

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AI Contract Overview

The National Cancer Institute, under the Department of Health and Human Services, is seeking applications to investigate the causes and biological mechanisms of sporadic non-hereditary early-onset cancers in adults aged 18 to 49. The primary goal of this initiative is to understand the rise of these cancers by examining modifiable exposures, host responses, and methods for more effective identification of high-risk individuals to improve prevention and control strategies. Applicants may choose between two funding paths: an exploratory or developmental research project lasting up to two years, or a full research project spanning four to five years. This consolidated funding mechanism is designed to streamline the application process and accelerate research into the etiology of early-onset cancers.

General Info

Funding for research on causes, biology, and prevention of early-onset sporadic cancers in young adults.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

Not specified

Set-Aside

NONE

Documents

(0)

No documents available

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Timeline

PostedMar 10

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Organization & Contact Information

AgencyDepartment Of Health And Human Services → National Institutes Of Health

Contacts1 person available

OfficeUSA

Organization / AgencyDepartment Of Health And Human Services → National Institutes Of Health

Office AddressUSA

Contacts

Epidemiology and Genomics Research Program

contact@example.gov

+1 (555) 000-0000

Full Description

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) invites applications that investigate the etiology of sporadic non-hereditary early-onset cancers (EOCs: ages 18 to 49 years) and the underlying biological mechanisms that play a role in these cancers to inform prevention and control strategies. The proposed research is expected to advance the understanding of the unexplained rise of cancers in young adults. More specifically, studies should address one or more of the following: i) what modifiable exposures are driving the increase in the incidence of non-hereditary EOCs, and how do these factors vary by patient demographics? (ii) what biological mechanisms and host responses underly the increase in EOCs? and (iii) how can those at increased risk for developing EOCs be identified more effectively?

This NOFO consolidates exploratory/developmental and research project funding mechanisms to streamline the application process and sustain momentum in this critical research area. Applicants have the option of submitting either an exploratory/developmental research project with a project period of up to 2 years or a research project with a project period of 4 to 5 years.