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This Government Contract opportunity from Department Of Health And Human Services was posted on June 22, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

Electrophysiology and Live-Cell Imaging Integration

Closed
Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541715
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Solicitation # HQ0860-25-S-C001
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AI Contract Overview

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The contract seeks integration capabilities that enable simultaneous patch-clamp electrophysiology and live pharmacological manipulation coupled with high-speed imaging, all while minimizing phototoxicity during live-cell experiments. This requires a system that synchronizes precise electrical recording with real-time drug delivery and fast, low-impact optical imaging to capture dynamic cellular responses without compromising cell viability. The solution must achieve high temporal and spatial resolution, ensuring that physiological data and pharmacological effects are correlated accurately under physiologically relevant conditions. The opportunity is a small business set-aside under NAICS code 541715, issued by the National Institutes of Health NICHD under the Department of Health and Human Services, with performance based in Bethesda, Maryland. Subcontractors must respond by June 24, 2026, and the project emphasizes innovation in biomedical instrumentation, targeting advancements that support neurobiological and cellular pharmacology research. The technical requirements prioritize minimizing light-induced damage to keep cells healthy during prolonged imaging sessions, making the development of efficient, low-intensity illumination techniques and seamless hardware-software integration essential.

General Info

Develop integrated electrophysiology, drug delivery, and low-phototoxicity imaging system for neurobiological research in Bethesda.

Agency

Department Of Health And Human Services → National Institutes Of Health NichdView Agency

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)View NAICS

Place of Performance

Bethesda, MD, 20892, USA

Set-Aside

SBA

Documents

This scope was carved out of 75N98026R00105.

The full solicitation package (1 document), including the RFP, is on the prime solicitation, not on this scope.

View the prime solicitation

Nikon AX R with Nikon Spatial Array ConfocalMicroscope System.

AI Contract Breakdown

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Timeline

PhaseClosed
Posted

subcontract

Response Deadline

Deadline has passed

Submission Closed

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health Nichd
ContactsNo contacts available
OfficeN/A
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health Nichd
View Agency Profile
Office AddressN/A
ContactsNo contact information available

Full Description

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Provide integration capability for simultaneous patch-clamp electrophysiology and live pharmacological manipulation with high-speed imaging, minimizing phototoxicity in live-cell experiments.

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