This Government Contract opportunity from Department Of Health And Human Services was posted on June 22, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Electrophysiology and Live-Cell Imaging Integration

Closed

Federal

Submission Closed06/24/2026, 09:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541715

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FA2391 USAF Afmc Afrl Pzl Afrl Rqkp

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Solicitation # 89233127RNA000340

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Protocol Monitoring and Data Management SupportThis subcontract opportunity, titled Protocol Monitoring and Data Management Support, involves providing clinical trial protocol monitoring and research data management for prime contractors on NIH/NHGRI clinical research projects. The scope of work includes monitoring clinical research protocols, managing data services, and developing transition and startup documentation to deliver validated research datasets and monitored protocol reports. Performance will take place in Bethesda, and the project is categorized under NAICS code 541715. The contract is designated as a Total Small Business Set Aside for the National Institutes of Health under the Department of Health and Human Services. To ensure regulatory compliance, the selected provider must adhere to NIH ICO Information Security and Privacy certifications and execute a Business Associate Agreement for HIPAA compliance. Responses are due by November 13, 2026.

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AI Contract Overview

The contract seeks integration capabilities that enable simultaneous patch-clamp electrophysiology and live pharmacological manipulation coupled with high-speed imaging, all while minimizing phototoxicity during live-cell experiments. This requires a system that synchronizes precise electrical recording with real-time drug delivery and fast, low-impact optical imaging to capture dynamic cellular responses without compromising cell viability. The solution must achieve high temporal and spatial resolution, ensuring that physiological data and pharmacological effects are correlated accurately under physiologically relevant conditions. The opportunity is a small business set-aside under NAICS code 541715, issued by the National Institutes of Health NICHD under the Department of Health and Human Services, with performance based in Bethesda, Maryland. Subcontractors must respond by June 24, 2026, and the project emphasizes innovation in biomedical instrumentation, targeting advancements that support neurobiological and cellular pharmacology research. The technical requirements prioritize minimizing light-induced damage to keep cells healthy during prolonged imaging sessions, making the development of efficient, low-intensity illumination techniques and seamless hardware-software integration essential.

General Info

Develop integrated electrophysiology, drug delivery, and low-phototoxicity imaging system for neurobiological research in Bethesda.

Agency

Department Of Health And Human Services → National Institutes Of Health Nichd

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

Bethesda, MD, 20892, USA

Set-Aside

SBA

Documents

This scope was carved out of 75N98026R00105.

The full solicitation package (1 document), including the RFP, is on the prime solicitation, not on this scope.

View the prime solicitation

Nikon AX R with Nikon Spatial Array ConfocalMicroscope System.

AI Contract Breakdown

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Timeline

PhaseClosed

PostedJun 22

subcontract

Response DeadlineJun 24

Deadline has passed

Submission Closed

06/24/2026, 09:00:00 PM UTC

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Organization & Contact Information

AgencyDepartment Of Health And Human Services → National Institutes Of Health Nichd

ContactsNo contacts available

OfficeN/A

Organization / AgencyDepartment Of Health And Human Services → National Institutes Of Health Nichd

Office AddressN/A

ContactsNo contact information available

Full Description

Provide integration capability for simultaneous patch-clamp electrophysiology and live pharmacological manipulation with high-speed imaging, minimizing phototoxicity in live-cell experiments.